Clinical trials: Chemotherapy Symptoms
Fatigue, Cognitive Impairment
Cognitive Function After Stem Cell Transplantation
The trial will evaluate the effects of an exercise program on the physical and cognitive performance of patients with hematological neoplastic diseases after high dose chemotherapy with stem cell support.
- Conditions
- Fatigue, Cognitive Impairment, Stem Cell Transplantation
- Trial name
- NCT00884338
- Testing
- Endurance exercise, Counseling
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Lymphoma
Peripheral Stem Cell Transplantation With Specially Treated Stem Cells in Treating Patients With Non-Hodgkin's Lymphoma or Hodgkin's Disease
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells.
- Trial name
- NCT00005998
- Testing
- carmustine, cyclophosphamide, cytarabine
- Sponsor
- Masonic Cancer Center, University of Minnesota
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Concomitant Limb Cryocompression and Scalp Cooling to Reduce Paclitaxel-induced Neuropathy and Alopecia
Paclitaxel is a chemotherapy drug that is used to treat breast cancer, one of the most common cancers. It causes two side effects very often - hair-loss and numbness.
- Trial name
- NCT03248193
- Testing
- Concomitant limb cryocompression and scalp cooling
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Atrial Fibrillation
Low-dose NOAC Versus GDMT After LAAO
The increased risk of Atrial fibrillation (AF) regarding thromboembolic stroke is predominantly due to the formation and embolization of clots from within the left atrial appendage (LAA).
- Trial name
- RECORD-III (NCT05960721)
- Testing
- Rivaroxaban 15mg, Aspirin 100mg, Clopidogrel 75mg
- Where
- China
- Volunteers
- 4,220 people
- Sponsor
- Xijing Hospital
Breast Cancer
Barriers to Therapeutic Exercise in Breast Cancer Patients Before, During, and After Chemotherapy
Cancer is one of the leading causes of mortality. First-choice cancer treatments, such as chemotherapy, have increased the survival of people with cancer, although they are not without adverse effects such as cardiotoxicity…
- Trial name
- NCT06828614
- Testing
- Chemotherapy
- Where
- Spain
- Volunteers
- 111 people
- Sponsor
- University of Valencia
Cancer
Detection of Chemotherapy Induced Cardiotoxicity
To identify patients that are at risk of heart damage after receiving chemotherapy (adriamycin).
- Trial name
- NCT00636844
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- George Washington University
Major Depressive Disorder
Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
The purpose of this study is to determine the effectiveness and safety of vortioxetine, once daily (QD), in patients with Major Depressive Disorder.
- Trial name
- NCT00735709
- Testing
- Vortioxetine
- Where
- 48 sites in Australia, Czechia and 13 more
- Volunteers
- 560 people
- Sponsor
- Takeda
Cancer
Sensory Approach of Food Modifications Led by Chemotherapy
The aim of the present study was to evaluate the impact of chemotherapy on sensorial perception in lung cancer patients in comparison to a control group (individuals without lung cancer and chemotherapy treatment).
- Trial name
- ARC-1 (NCT02368509)
- Testing
- Perform sensory tests
- Where
- 3 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cancer of Unknown Primary Site
A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site
This study will compare the efficacy and safety of molecularly-guided therapy versus standard platinum-containing chemotherapy in participants with poor-prognosis cancer of unknown primary site (CUP; non-specific subset) who have…
- Trial name
- CUPISCO (NCT03498521)
- Testing
- Alectinib, Vismodegib, Ipatasertib
- Where
- 125 sites in Australia, Austria and 31 more
- Volunteers
- 529 people
- Sponsor
- Hoffmann-La Roche
Neoplasm Metastasis, Neoplasm Recurrence
PG2 Phase I/II Clinical Study Intravenously Administered in Patients With Advanced Malignancy
The objectives of this Phase I/II study are: 1. To find out the maximum tolerated dose (MTD) of PG2 in patients with advanced malignancy receiving chemotherapy and to define a "Study Dose" for Phase II. 2.
- Trial name
- NCT01696565
- Testing
- PG2
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- PhytoHealth Corporation
Leukemia, Myelocytic, Acute
Cladribine, Cytarabine and Idarubicin in Patients With Relapsed Acute Myelocytic Leukemia (AML)
The purpose of this study is to evaluate the safety and the efficacy of cladribine, high-dose cytarabine and idarubicin in the treatment of patients with relapsed acute myeloid leukemia.
- Trial name
- NCT00126321
- Testing
- cladribine
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bonn
Metastatic Cancer
A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function
The purpose of this study is to evaluate the safety and pharmacokinetics of ASA404 in patients with refractory or relapsed metastatic cancer with impaired renal function and with normal renal function.
- Trial name
- NCT01278758
- Testing
- ASA404, DMXAA or DXAA
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- Novartis Pharmaceuticals
Heartburn, Gastroesophageal Reflux Disease
Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients
The purpose of this study is to determine the efficacy and safety of dexlansoprazole compared to placebo in relief of daytime and nighttime heartburn over 4 weeks in Chinese participants with symptomatic non-erosive…
- Trial name
- NCT02873689
- Testing
- Dexlansoprazole
- Where
- 25 sites in China
- Volunteers
- 217 people
- Sponsor
- Takeda
Cardiovascular Diseases, Myocardial Infarction
Effect of Drug Therapy on Reinfarction Risk in Women
To evaluate the safety of calcium-channel blockers in the secondary prevention of myocardial infarction in women.
- Conditions
- Cardiovascular Diseases, Myocardial Infarction, Heart Diseases
- Trial name
- NCT00005389
- Sponsor
- University of Washington
Hematological Neoplasm, Graft-Versus-Host Disease
The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell Transplantation
The allogenic stem cell transplantation (aSCT), the only curative approach for many hematological diseases, often leads to severe diseases or chronic conditions, leaving patients with physical disabilities and severe depression…
- Conditions
- Hematological Neoplasm, Graft-Versus-Host Disease, Depression, Stem Cell Transplant Complications
- Trial name
- TriCAM (NCT02976558)
- Testing
- Clown theatrical Performance, Acupuncture, Music Therapy TaKeTiNa
- Where
- Germany
- Volunteers
- 104 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Liver Cancer (Primary and Metastatic)
A Study of Combination Therapy in Patients With Resectable Liver Cancer
This is a prospective, single-arm clinical study designed to evaluate the efficacy and safety of an initial combination treatment strategy followed by surgery in patients with cancer.
- Trial name
- Archer (NCT07684040)
- Testing
- Hepatic Arterial Infusion Chemotherapy Combined with Adebrelimab Plus Rivoceranib
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Acute Myeloid Leukemia, Neutropenia
Home Away From Home - Medical Outcomes
Treatment for pediatric acute myeloid leukemia (AML) involves intensive chemotherapy regimens that result in periods of profound neutropenia leaving patients susceptible to severe infectious complications.
- Conditions
- Acute Myeloid Leukemia, Neutropenia, Bacteremia
- Trial name
- Aim 1 (NCT02774850)
- Where
- 17 sites in United States
- Volunteers
- 610 people
- Sponsor
- Children's Hospital of Philadelphia
Chemotherapy-induced Peripheral Neuropathy
Whole-body Vibration Training to Reduce the Symptoms of Chemotherapy-induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and clinically meaningful side effect of cancer treatment.
- Trial name
- VANISH (NCT03032718)
- Testing
- Whole-body vibration training
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Basel
Metastatic Breast Cancer
SU11248 as Consolidation After Response to Taxanes in Metastatic Breast Cancer
This study tests the hypothesis that SU11248 can delay tumor progression after tumor mass reduction by taxanes. This is a dual-arm open-label randomized multicenter phase II clinical trial with 2:1 randomization evaluating the…
- Trial name
- NCT00270413
- Testing
- SU11248
- Where
- 13 sites in Belgium
- Volunteers
- 19 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer, Chemotherapeutic Agent Toxicity
Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast Cancer
RATIONALE: Gathering information over time from laboratory tests, imaging scans, and assessment tests may help doctors learn more about the side effects of chemotherapy and plan the best treatment.
- Conditions
- Breast Cancer, Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Fatigue
- Trial name
- NCT00755313
- Testing
- trastuzumab, aromatase inhibition therapy, carboplatin
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.