Clinical trials: Chemotherapy-Induced Peripheral Neuropathy
Neuropathy, Oncology
Exercise Intervention for Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common adverse effect of chemotherapy that can negatively impact patients' functional status and quality of life.
- Conditions
- Neuropathy, Oncology, Exercise, Effectiveness
- Trial name
- NCT07635901
- Testing
- Structured exercise program for CIPN
- Where
- India
- Volunteers
- 282 people
- Sponsor
- Sri Ramachandra Institute of Higher Education and Research
Chemotherapy-induced Peripheral Neuropathy
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of many forms of chemotherapy having a negative impact on the quality of life for cancer survivors due to numbness, decreased sensation, pain (of various…
- Trial name
- NCT03272919
- Testing
- Arm 1: Investigational INF, Arm 2: standardized muscle stretching and strength
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loma Linda University
Breast Neoplasms, Over Cancer
The Effect of Foot Massage With Roles on Cancer Patients
It was aimed to examine the roles in the management of treatment-related peripheral neuropathy in cancer patients receiving taxane-based chemotherapy and the effect of foot massage on neuropathy and quality of life.
- Conditions
- Breast Neoplasms, Over Cancer, Foot Massage
- Trial name
- NCT06376357
- Testing
- Foot Massage with roller
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Selcuk University
Cancer, Malignancy
Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy
Problem: A significant proportion of patients with cancer experience symptoms of sensory, motor or autonomic nerve damage from chemotherapy known as chemotherapy-induced peripheral neuropathy (CIPN).
- Conditions
- Cancer, Malignancy, Malignant Neoplasm, Neuropathy
- Trial name
- NCT03909464
- Testing
- Neurosensory testing with Pressure-Specified Sensory Device
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Acute Pain, Breast Carcinoma
Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel
This randomized pilot trial studies how well minocycline hydrochloride works in reducing chemotherapy-induced peripheral neuropathy and acute pain in patients with breast cancer undergoing treatment with paclitaxel.
- Conditions
- Acute Pain, Breast Carcinoma, Peripheral Neuropathy
- Trial name
- NCT02297412
- Testing
- Minocycline Hydrochloride, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 12 sites in United States
- Volunteers
- 47 people
- Sponsor
- Academic and Community Cancer Research United
Breast Cancer, Colorectal Cancer
Chemotherapy-Induced Peripheral Neuropathy Survey
The goal of this research study is to learn more about pain and other symptoms that patients may experience while receiving chemotherapy treatment with platinum agents, taxanes, and/or bortezomib.
- Conditions
- Breast Cancer, Colorectal Cancer, Myeloma, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT01016028
- Testing
- Questionnaire, Sensory Tests, Interview
- Sponsor
- M.D. Anderson Cancer Center
Chemotherapy-induced Peripheral Neuropathy
Evaluation by Oncologists of Strategies for the Prevention and Treatment of Chemotherapy-induced Peripheral Neuropathies
Chemotherapy induced peripheral neuropathy (CIPN) is one of the most deleterious adverse effect of neurotoxic anticancer drugs affecting up to 40% of patients.
- Trial name
- EVANEURO (NCT03854864)
- Testing
- survey
- Where
- France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Breast Cancer
Effectiveness of Cryotherapy Combined With Compression Therapy for Preventing Chemotherapy-induced Peripheral Neuropathy
This is a prospective, multi-center, randomized study designed to evaluate the clinical efficacy of cryotherapy combined with compression therapy in preventing albumin-paclitaxel induced peripheral neuropathy.
- Trial name
- NCT05341141
- Testing
- Frozen glove and sock, ddEC-ddT
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Peking University
Pain, Peripheral Neuropathy
The Purpose of This Study is to Determine if Tetrodotoxin (TTX) is Effective in the Treatment of Pain Resulting From Chemotherapy Treatment
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect of many chemotherapeutic agents including vincristine, paclitaxel, cisplatin, oxaliplatin, bortezomib and ixabepilone.
- Conditions
- Pain, Peripheral Neuropathy, Neuropathic Pain
- Trial name
- TTX-CINP-201 (NCT01655823)
- Testing
- Tetrodotoxin
- Where
- 23 sites in United States
- Volunteers
- 125 people
- Sponsor
- Wex Pharmaceuticals Inc.
Neuropathic Pain, Distal Sensory Polyneuropathy
Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
The purpose of this study is to evaluate how safe and how well a treatment works compared to placebo for people with nerve pain that begins in their feet and moves up the leg to just below the knee.
- Trial name
- NCT06568042
- Testing
- LY3848575
- Where
- 76 sites in United States, Canada and 5 more
- Volunteers
- 558 people
- Sponsor
- Eli Lilly and Company
Chemotherapy Induced Peripheral Neuropathy (CIPN), Peripheral Neuropathy Due to Chemotherapy
Feasibility Testing of a Tai Chi Program for Chemotherapy-Induced Peripheral Neuropathy Treatment (TCT)
This research is being done to determine whether a 12-week virtual Tai Chi training program, designed to improve balance and small nerve fiber function, is feasible and acceptable among cancer survivors with chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathies, Neuropathy
- Trial name
- NCT06807294
- Testing
- Tai Chi Program
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Dana-Farber Cancer Institute
Neuropathic Pain, Chemotherapy Induced Pain Neuropathy
The Effect of Foot Massage With a Massage Roller on Chemotherapy-Related Neuropathic Pain
Chemotherapy-related neuropathic pain is experienced by 30-40% of cancer patients. This pain significantly reduces the quality of life and overall well-being of patients battling cancer.
- Trial name
- NCT07650864
- Testing
- Roller Massage, Ice therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Peripheral Neuropathy Due to Chemotherapy
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy
Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of taxanes and platinum derivative based chemotherapeutic agents, common in breast cancer treatment regimens.
- Trial name
- NCT03571334
- Testing
- IncobotulinumtoxinA (Xeomin®, Merz) (INA), Normal saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Peripheral Neuropathy
Treatment Trial Using Low Level Laser Therapy (LLLT) for Treatment of Chemotherapy Induced Peripheral Neuropathy
The purpose of this research study is to determine if treatment with Low Level Laser Therapy (LLLT) is effective in treating the pain, numbness or tingling patients are experiencing following their chemotherapy.
- Trial name
- LLL (NCT01006408)
- Testing
- Low Level Laser
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Legacy Health System
Radiation Toxicity, Chemotherapeutic Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms, who have been referred to the HUGCDN Chronic Pain Unit for adjuvant palliative treatment with…
- Conditions
- Radiation Toxicity, Chemotherapeutic Toxicity, Chemotherapy-induced Peripheral Neuropathy, Delayed Wound Healing
- Trial name
- EPOOzo (NCT05417737)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Bernardino Clavo, MD, PhD
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy
Risk Prediction of Taxane Chemotherapy-Induced Peripheral Neuropathy
This is an observational study to discover risk factors of chemotherapy-induced peripheral neuropathy (CIPN) in 350 patients with early stage breast cancer undergoing taxane-based chemotherapy at two main sites (University of…
- Conditions
- Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Aging
- Trial name
- SENSE (NCT04932031)
- Where
- 2 sites in United States
- Volunteers
- 123 people
- Sponsor
- Sapere Bio
Breast Cancer
PBMT for the Prevention of CIPN
ne of the most common cancers in women worldwide is breast cancer. A common used therapy in early-stage and metastatic breast cancer involves chemotherapy.
- Trial name
- NCT03391271
- Testing
- photobiomodulation therapy (PBMT)
- Where
- Belgium
- Volunteers
- 53 people
- Sponsor
- Hasselt University
Peripheral Neuropathy
Pilot Study Investigating the Use of the ReBuilder to Treat Chemotherapy Induced Peripheral Neuropathy in Patients With Breast Cancer
The purpose of this study is to investigate the effect of the ReBuilder in the treatment of individuals with breast cancer and chemotherapy induced peripheral neuropathy.
- Trial name
- NCT02606110
- Where
- United States
- Sponsor
- Eastern Regional Medical Center
Chemotherapy-induced Peripheral Neuropathy (CIPN)
PREventing CHemotherapy Induced Neuropathy (PreChIN)
The project is designed to study the use of localized hypothermia alone, or with compression to the limbs during chemotherapy infusion for the prevention of chemotherapy induced peripheral neuropathy (CIPN).
- Trial name
- NCT03299582
- Testing
- Hypothermia, Cryocompression
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chemotherapy-induced Peripheral Neuropathy
A Novel Limb Cryocompression System for Prevention of Chemotherapy Induced Peripheral Neuropathy - Expansion Study
The study conducted on cancer patients is designed to test safety and efficacy of limb hypothermia in cancer patients using the new Paxman Limb Cryocompression System (PLCS).
- Trial name
- NCT05606068
- Testing
- Paxman Limb Cryocompression System (PLCS)
- Where
- 2 sites in Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore