Clinical trials: Chemotherapy-induced Peripheral Neuropathy (CIPN)
Chemotherapy-induced Peripheral Neuropathy
The Preliminary Effects of Henna on CIPN
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common long-term toxicities of chemotherapy. Though, CIPN is one of the common symptoms encountered by oncology nurses in care of patients.
- Trial name
- NCT04201587
- Testing
- Henna application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe side effect of several anti-cancer agents. Typical symptoms include tingling and hypoesthesia in the fingertips and/or toes, which substantially impair patients'…
- Trial name
- Assess CIPN (NCT07315334)
- Testing
- Questionnaire and Physical Exam
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Chemotherapy-induced Peripheral Neuropathy
Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation
Over half of cancer patients receiving common chemotherapy treatments experience painful nerve damage called chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NIBS4CIPN (NCT06522685)
- Testing
- transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Morgan State University
Peripheral Neuropathy
Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy
The purpose of this study is to test whether people with symptoms of chemotherapy-induced peripheral neuropathy (CIPN) receive physical or psychological benefits from participating in a six-week Reiki, Yoga, Meditation, or…
- Trial name
- NCT01569269
- Testing
- Yoga Intervention, Meditation Intervention, Reiki
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- George Mason University
Peripheral Neuropathy
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer
Purpose: The purpose of the study is to test a new way of measuring nerve damage in women with breast cancer receiving chemotherapy drug paclitaxel (Taxol).
- Trial name
- NCT02549534
- Testing
- Axon Reflexes, Axon Flares, Self-Reported Signs & Symptoms of CIPN
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chemotherapy-induced Peripheral Neuropathy
The Role of TRP Channels in CIPN
Part I: Evaluating the increase in dermal blood flow upon topical application of cinnamaldehyde and capsaicin on the fingers in healthy, male volunteers.
- Trial name
- NCT04415892
- Testing
- Cinnamaldehyde and capsaicin
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chemotherapy-induced Peripheral Neuropathy (CIPN)
PREventing CHemotherapy Induced Neuropathy (PreChIN)
The project is designed to study the use of localized hypothermia alone, or with compression to the limbs during chemotherapy infusion for the prevention of chemotherapy induced peripheral neuropathy (CIPN).
- Trial name
- NCT03299582
- Testing
- Hypothermia, Cryocompression
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chemotherapy Induced Peripheral Neuropathy (CIPN)
SUNCIST: A Study of Calmangafodipir in Healthy Japanese and Caucasian Subjects
Randomized, double-bline, placebo-controlled, single dose study comparing the pharmacokinetics (PK) and safety of PP095-01 in Japanese and non-Asian (eg, Caucasian) subjects.
- Trial name
- NCT03430999
- Testing
- Calmangafodipir
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Egetis Therapeutics AB (publ)
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Safety, Tolerability, and PK of AH-008 Following Single Ascending Dose in Healthy Subjects
This is a Phase 1, first-in-human (FIH), randomized, double-blind, placebo-controlled, parallel-group, single ascending dose (SAD) study to evaluate the safety, tolerability, and pharmacokinetics of AH-008 administered as a…
- Trial name
- NCT07697560
- Testing
- AH-008 for Injection, 150 mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AnHorn Medicines Co. Ltd.
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Concomitant Limb Cryocompression and Scalp Cooling to Reduce Paclitaxel-induced Neuropathy and Alopecia
Paclitaxel is a chemotherapy drug that is used to treat breast cancer, one of the most common cancers. It causes two side effects very often - hair-loss and numbness.
- Trial name
- NCT03248193
- Testing
- Concomitant limb cryocompression and scalp cooling
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy
The Influence of Chemotherapy on Position Sense
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent side-effects of chemotherapy, causing sensory and motor symptoms in patients.
- Conditions
- CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
- Trial name
- ProprioCIPN (NCT07367711)
- Testing
- Questionnaire - Edinburgh Handedness Assessment, Questionnaire - QuickDash, Questionnaire - EORTC QLQ-CIPN20
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Chemotherapy-induced Peripheral Neuropathy
Effect of Transcutaneous Electrical Nerve Stimulation on CIPN Symptoms
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most common and debilitating survivorship conditions for patients with cancer, and one of the most common side effects of chemotherapy treatment.
- Trial name
- NCT06499103
- Testing
- Transcutaneous electrical nerve stimulation
- Where
- Jordan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Continuous Controlled Cooling for Prevention of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain types of chemotherapy and can cause numbness, tingling, pain, and other symptoms in the hands and feet.
- Trial name
- COOL-tax (NCT07917026)
- Testing
- Continuous Controlled Cooling of the Hands and Feet
- Where
- Sweden
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Peripheral Nervous System Diseases
Pre-study to Evaluate IENFD Induction in Patients With Taxane-induced CIPN
This is a non-interventional study examining IENFD levels in patients with CIPN after taxane chemotherapy and in age-matched healthy subjects.
- Trial name
- NCT05133947
- Testing
- Non interventional
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Beijing 3E-Regenacy Pharmaceuticals Co., Ltd.
Chemotherapy-induced Peripheral Neuropathy (CIPN), Healthy
Relationship Between Great Toe Strength And Symptoms of Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Great Toe Strength (GTS) is a potential clinical biomarker that has been associated with functional mobility and health; Additionally, GTS has been identified in the literature as one of the early symptoms of chemotherapy-induced…
- Trial name
- NCT07009717
- Testing
- No intervention (observational study)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida