Clinical trials: Chest CT Scan
Lung Neoplasms, Emphysema
Computed Tomography Assessment of Regional Ventilation (CURVE)
This study uses CT scans to assess airflow in the lung, the scan is quick, cheap and painless. The information from the scan may help doctors tell which patients are suitable to have surgery to cure early stage lung cancer.
- Conditions
- Lung Neoplasms, Emphysema, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive
- Trial name
- CURVE (NCT02879773)
- Testing
- CTPVe
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Heart of England NHS Trust
Therapeutic Procedural Complication
Chest CT for the Placement of the Uniblocker
Video laryngoscope and chest CT iminge for the placement of the Uniblocker
- Trial name
- NCT03008473
- Testing
- video laryngoscope and chest CT iminge, Conventional intubation of uniblocker
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The First Hospital of Qinhuangdao
Lung Cancer
Novel Lung Functional Imaging for Personalized Radiotherapy
The primary objective of this study is to assess the safety and feasibility of personalized radiotherapy with four-dimensional (4D) computed tomography (CT)-based pulmonary ventilation imaging, which selectively avoids…
- Trial name
- NCT02308709
- Testing
- Ventilation image-guided radiotherapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, Davis
Tuberculosis, Pulmonary, Latent Tuberculosis
Early Diagnosis of Active Tuberculosis Using Ultra Low-dose Chest CT
The aim of this study is to evaluate ultra low dose chest computed tomography (ULDCT) for early diagnosis of active tuberculosis in cohort of close contacts of active pulmonary tuberculosis for 1 year follow up
- Trial name
- NCT03220464
- Testing
- Ultra low dose chest computed tomography (ULDCT), Chest X-ray, Interferon-gamma Release Assay (IGRA)
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Lung Neoplasms, Lung Cancer
Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54
Low-dose CT Screening has been shown in two large trials in the United States (NLST) and Europe (NELSON) to increase overall survival in subjects 55 years of age and older with a strong smoking history.
- Trial name
- NCT04577599
- Testing
- Mobile Low-dose Computed Tomography (LDCT) Screening
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pneumonia
Screening for Pneumonia: A Comparison of Ultra Low Dose Chest CT [ULD-CT] and Conventional Chest Radiography [CXR]
The ULTRACHEST study will be a prospective clinical diagnostic performance study with primary objective to establish device diagnostic clinical performance of Ultra Low Dose CT (ULD-CT) in order to prove it is more accurate in…
- Trial name
- ULTRACHEST (NCT03140163)
- Testing
- ULD-CT, CXR
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stage I Pulmonary Adenocarcinoma
Prognostic Role of Positron Emission Tomography and Computed Tomography Parameters in Stage I Lung Adenocarcinoma
The clinical and derived data from the preoperative computed axial tomography (CT) and Positron Emission Tomography (PET) of patients with pathological stage I pulmonary adenocarcinoma will be analyzed retrospectively, classified…
- Trial name
- NCT04202614
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- IRCCS San Raffaele
Coronary Artery Disease
Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study)
The FLOW-PROMOTE Study is an investigator-initiated, Danish multicenter study of patients with stable chest pain investigating whether lipid lowering is associated with recovery of impaired coronary flow as assessed by CT derived…
- Trial name
- FlowPromote (NCT04737408)
- Testing
- Rosuvastatin 40mg
- Where
- 3 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Bjarne Linde Noergaard
Thoracic Neoplasm, Pulmonary Nodules
Study of Collection and Analysis of Clinical, Anamnestic, Functional, Biological Data Through the Support of Artificial Intelligence to Evaluate the Possibility of Defining a Digital Twin of the Lung (LUCE)
This research study aims to retrospectively and prospectively analyze the clinical, anamnestic, functional, biological data of patients who have performed or will perform non-contrast chest photon count CT.
- Conditions
- Thoracic Neoplasm, Pulmonary Nodules, Non-oncological Pulmonary Pathologies
- Trial name
- NCT07517393
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Systemic Sclerosis
Chest CT Biomarkers as Prognostic Predictors in SSc-ILD
The goal of this retrospective observational study is to investigate whether novel imaging biomarkers of airways, vessels, and overall extent of fibrosis at baseline predict ILD progression, vasculopathy development, and survival…
- Trial name
- NCT06472362
- Testing
- HRCT biomarkers
- Where
- 7 sites in France, Germany and 2 more
- Volunteers
- 1,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Coronary Artery Disease of Significant Bypass Graft, Coronary Syndrome
Implementation of Contemporary Coronary CT Angiography in Clinical Practice
Coronary CT angiography (CCTA) has been recognized as the first-line diagnostic test for most patients with suspected coronary syndrome, often acting as a gatekeeper for invasive coronary angiography.
- Conditions
- Coronary Artery Disease of Significant Bypass Graft, Coronary Syndrome, Coronary Arteriosclerosis
- Trial name
- CONCORDE (NCT06273033)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Humanitas Hospital, Italy
Lung Cancer
Retrospective Epidemiological Study of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival.
- Trial name
- NCT02736643
- Volunteers
- 1,334 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Cancer
AI-Assisted Chest CT Interpretation Across the Lung Cancer Care Continuum
This investigator-initiated, single-center study consists of a retrospective artificial intelligence model-development stage and a prospective physician reader-study stage.
- Trial name
- NCT07829640
- Testing
- Chest CT Artificial Intelligence Decision-Support System
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Cystic Fibrosis
Controlled Ventilation CT in CF Infants
The objective of the study is to implement a new method of performing chest CT imaging in young children with cystic fibrosis at Packard Children's Hospital.
- Trial name
- NCT01200888
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Cardiology, Radiology
The Evaluation of the Roles of New Cardiac Imaging in Patients With Chest Pain
This is a prospective, observational study designed to evaluate the role of dynamic computed tomographic perfusion (CTP) and Computed Tomography-Derived Fractional Flow Reserve (CT-FFR) in patients presenting with chest…
- Conditions
- Cardiology, Radiology, Stenoses
- Trial name
- NCT03800862
- Testing
- CT-FFR and CTP
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Lancaster General Hospital
Respiratory Failure
Influence of Chest X-ray vs. Chest CT Scan on the Management of ICU Patients With Respiratory Failure
Patients admitted to the intensive care unit (ICU) often require CT imaging. Performing this test on a critically ill patient involves risks, such as those associated with transferring a ventilated and unstable patient…
- Trial name
- NCT07256860
- Testing
- Chest computed tomography scan
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Chest Pain
Coronary Computed Tomography (CT) Angiography Versus Standard Therapy in the Emergency Room
The purpose of this study is to determine the usefulness of CCTA (Coronary Computed Tomography Angiography) in the emergency room setting to diagnose and predict the outcome of patients with chest pain who have a low to moderate…
- Trial name
- NCT00846469
- Testing
- CCTA (coronary computed tomography angiography), Control section
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Pulmonary Nodules
Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules
AnchorDx is using circulating tumor DNA (ctDNA) methylation analysis by next-generation sequencing (NGS) to develop a blood-based assay for differentiating benign and malignant pulmonary nodules early.
- Trial name
- NCT03651986
- Testing
- ctDNA methylation analysis by NGS
- Where
- 23 sites in China
- Volunteers
- 10,560 people, healthy volunteers welcome
- Sponsor
- AnchorDx Medical Co., Ltd.
Thoracic Aortic Aneurysm
Thoracoabdominal Arortic CTA Study
The purpose of this study is to compare the contrast agents and imaging techniques used for thoracoabdominal aortic imaging in CT.
- Trial name
- NCT02291718
- Testing
- Isovue
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Lung Cancer
Integrating Artificial Intelligence Into Lung Cancer Screening.
Lung cancer (LC) screening using low-dose chest CT (LDCT) has already proven its efficacy. The mortality reduction associated with LC screening is around 20%, much higher than the reduction in mortality associated with screening…
- Trial name
- DACAPO (NCT05704920)
- Testing
- IA, Not IA
- Where
- France
- Volunteers
- 2,722 people
- Sponsor
- Centre Hospitalier Universitaire de Nice