Clinical trials: Chest CT Scan
Lung Cancer
Early Stage Lung Cancer Screening With Low-dose Computed Tomographic
The present study is a randomized controlled trial of LDCT screening for lung cancer versus usual care. 6000 high-risk subjects (age 45-70) were recruited and randomized to the Active arm (Baseline + 2 biennial repeated LDCT…
- Trial name
- NCT02898441
- Testing
- Low Dose Computed Tomography
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation (AF), Ischemic Stroke
Prediction of Stroke Risk in Patients with Atrial Fibrillation Based on Chest CT Images
This study aims to create and assess a deep learning framework for extracting left atrial appendage features in atrial fibrillation patients and combining them with clinical data to predict ischemic stroke risk.
- Trial name
- NCT06611995
- Testing
- observational study
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Therapeutic Procedural Complication
A Comparison the Intubation of a Left Sided Double Lumen Tube and Uniblocker
One-lung ventilation (OLV) is required for the most thoracic surgery to facilitate surgical visualization by collapsing the lung.
- Trial name
- NCT03392922
- Testing
- Uniblocker, Left-sided Double-lumen Tube
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Hospital of Qinhuangdao
Coronary Artery Disease
Fractional Flow Reserve Derived From Computed Tomography Coronary Angiography in the Assessment and Management of Stable Chest Pain
To determine whether, in a population of patients presenting to the rapid access chest pain clinic (RACPC), routine FFRct (Fractional Flow Reserve Computed Tomography) as a default test is superior in terms of resource…
- Trial name
- FORECAST (NCT03187639)
- Testing
- FFRct, Standard care
- Where
- United Kingdom
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Lung Neoplasms, Respiratory Tract Neoplasms
Alberta Lung Cancer Screening Program
Lung cancer is the leading cause of cancer death in North America and in the world. The vast majority of lung cancers are associated with cigarette smoking.
- Trial name
- NCT02431962
- Testing
- Computed Tomography, Active smokers - Smoking cessation arm, Active smokers - Control arm
- Where
- 2 sites in Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Non-small Cell Lung Cancer, Neoadjuvant Chemoimmunotherapy
Deep Learning Signature for Predicting Complete Pathological Response to Neoadjuvant Chemoimmunotherapy in Non-small Cell Lung Cancer
The purpose of this study is to evaluate the performance of a CT/PET/ WSI-based deep learning signature for predicting complete pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
- Conditions
- Non-small Cell Lung Cancer, Neoadjuvant Chemoimmunotherapy, Complete Pathological Response
- Trial name
- NCT05925751
- Testing
- CT/PET/WSI-based Deep Learning Signature
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Chest Pain
Low Dose One-Day Tc99m Protocol With a High-Efficiency Cardiac Dedicated Gamma Camera For Detection of Coronary Disease
A prospective single clinical trial to validate the use of a low-dose (~5mSv) Tc-99m protocol with a high-efficiency cardiac dedicated camera (Dynamic Single Photon Emission Computed Tomography; D-SPECT) to detect myocardial…
- Trial name
- NCT01135095
- Testing
- low-dose imaging
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Spectrum Dynamics
COPD With Coronary Artery Calcificatio
A TwiCs Study of TCM Management Based on Cardiopulmonary Screening in COPD
This clinical study seeks to understand whether, for people with stable COPD and coronary artery calcification found on chest CT, adding traditional Chinese medicine (TCM) health guidance (including dietary guidance) based on CT…
- Trial name
- NCT07900763
- Testing
- TCM-Based Health Management Guided by Coronary Artery Calcium Scores
- Volunteers
- 200 people
- Sponsor
- Henan University of Traditional Chinese Medicine
covid19
Lung CT Scan Analysis of SARS-CoV2 Induced Lung Injury
This is a multicenter observational retrospective cohort study that aims to study the morphological characteristics of the lung parenchyma of SARS-CoV2 positive patients identifiable in patterns through artificial intelligence…
- Trial name
- TAC-COVID19 (NCT04395482)
- Testing
- Lung CT scan analysis in COVID-19 patients
- Where
- 8 sites in Italy, San Marino
- Volunteers
- 44 people
- Sponsor
- University of Milano Bicocca
Inspiration Expiration Thoracic TDM Sequences of Patients With Diffuse Interstitial Lung Disease (DIP)
Digital Modeling of Thoracic CT and Pulmonary Fibrosis
Currently, to our knowledge, there is little data on the combination of tools based on a similar concept to understand and evaluate ILDs.
- Trial name
- MLQ-CT (NCT06618924)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer, Lung Function Decreased
Use of Dual Energy Computed Tomography in Thoracic Radiotherapy Planning.
This is a prospective observational study aiming: 1) To quantify lung function using perfusion dual energy computed tomography (DECT) and use this information at the time of treatment planning with preferential sparing of…
- Conditions
- Lung Cancer, Lung Function Decreased, Radiation Pneumonitis
- Trial name
- NCT04863027
- Testing
- Thoracic radiotherapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Coronary Syndrome, Coronary Artery Disease
Pilot Safety Study of Coronary CTA for the Diagnosis of Acute Coronary Syndrome in the Emergency Room
The Diagnosis of acute coronary syndrome in patients presenting with acute chest pain is problematic when both, electrocardiogram and serum troponins are normal.
- Conditions
- Acute Coronary Syndrome, Coronary Artery Disease, Cardiac Death, Myocardial Infarction
- Trial name
- NCT01682096
- Testing
- computed coronary angiography, Exercise stress echocardiography
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- José Ortiz
Lung Cancer, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Lung Cancer Prevention Screening Programme in Italy
This prospective randomized multicentered clinical study aims at implementing early diagnosis of lung cancer in high-risk heavy smokers in the Italian population.
- Conditions
- Lung Cancer, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection, Cardiovascular Diseases
- Trial name
- RISP (NCT05766046)
- Testing
- early lung cancer detection, blood test
- Where
- Italy
- Volunteers
- 7,324 people, healthy volunteers welcome
- Sponsor
- Ugo Pastorino
Carcinoma, Non-small Cell Lung Cancer
Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan
This is a single center, prospective and observational study conducted in three stages to predict the NSCLC lymph node metastasis based on ctDNA/specific methylation molecular features combined with PET-CT imaging features and…
- Trial name
- NCT06358222
- Testing
- Blood ctDNA + methylation + PET-CT and Postoperative pathology, MRD+ methylation (or combined with PET-CT) and Invasive mediastinoscopy /EBUS-TBNA, Intraoperative lymph node dissection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital