Clinical trials: Chest Infection
Covid19
Decision Support System Algorithm for COVID-19 Diagnosis
COVID-19 is an infectious disease caused by a newly discovered Coronavirus which was first identified in Wuhan, China in December 2019.
- Trial name
- NCT04479319
- Testing
- Thorax CT
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 3,215 people
- Sponsor
- Ankara University
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Mediastinitis
Infectious Mediastinitis Among the Strasbourg Universitary Hospital
Mediastinitis are rare but serious infections, with mortality rates varying from 6 to 30% according to the literature. They are essentially linked to surgical management (cardio-thoracic in particular), but some forms can be…
- Trial name
- MEDIASTINITIS (NCT05001308)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Children <24 Months Hospitalized for RSV-related Lower Respiratory Tract Infection
Severe Pediatric Respiratory Syncytial Virus Infections Occurring in the Era of Antiviral Prophylaxis
Hospitalization for RSV lower respiratory tract infections (LRTI) still occurs, including in infants having received nirsevimab/clesrovimab or born to mothers vaccinated with Abrysvo.
- Trial name
- SiRiUS (NCT07893652)
- Testing
- Prior exposure to prophylactic treatment with Abrysvo or nirsevimab/clesrovimab, Non-exposure to prior prophylactic treatment
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19
Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine
This is a double blind, placebo controlled study in approximately 2,000 health care workers at risk for being exposed to COVID-19.
- Trial name
- HERO-HCQ (NCT04334148)
- Testing
- Hydroxychloroquine
- Where
- 34 sites in United States
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- Adrian Hernandez
Lower Respiratory Tract Infections
Rapid Diagnostic Supporting Antimicrobial Stewardship in Patients With Pneumonia
The purpose of this study is to determine whether or not the FilmArray Penumonia Panel adds value to patient care.
- Trial name
- NCT05937126
- Testing
- FilmArray Pneumonia Panel, Culture and antimicrobial susceptibility testing
- Where
- United States
- Volunteers
- 1,203 people
- Sponsor
- Mayo Clinic
Lower Resp Tract Infection
Assessment of the Effectiveness of a Prototype Diagnostic System of Bacterial Respiratory Infections Based on Real-time Sequencing
The objective of this project is to test the efficiency of a novel developed protocol for direct real-time metagenomic sequencing of Lower Respiratory Infection samples.
- Trial name
- NCT07303400
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Cardiovascular Disease, Surgical Site Infection
Innovative Sternal Closure Techniques: Evaluating STRATAFIX™ and DERMABOND™ for Reduced Complications in CABG Patients
The goal of this clinical trial is to learn if a new method of closing the breastbone after heart bypass surgery can improve healing and reduce complications in adults undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Cardiovascular Disease, Surgical Site Infection, Superficial Sternal Wound Infection, Mediastinitis
- Trial name
- NCT07507409
- Testing
- Knotless Barbed Sutures, Mesh-based Topical Skin Adhesive
- Volunteers
- 401 people
- Sponsor
- Unity Health Toronto
Covid19
Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation
The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients…
- Trial name
- AI-SCoRE (NCT04834934)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Pneumonia
Accuracy of Clinical and Diagnostic Studies for Pneumonia in Children
Pneumonia continues to be a leading cause of death in children under five years of age worldwide. Many studies have evaluated clinical signs and symptoms that may predict pneumonia.
- Trial name
- NCT03630380
- Testing
- Clinical History, Physical Exam Findings, Laboratory Findings
- Where
- Nepal
- Volunteers
- 1,000 people
- Sponsor
- Patan Academy of Health Sciences
Cancer
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00049296
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center
Mediastinitis
Combined Air-plasma Flow and Nitric Oxide Therapy in Cardiac Surgery
In cardiovascular surgery, the most common and serious complication is postoperative wound infection. The most formidable wound complication is mediastinitis, the frequency of which varies from 1 to 3%.
- Trial name
- NCT04617353
- Testing
- NO-based treatment of sterno-mediastinitis, Treatment of sterno-mediastinitis
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Lower Respiratory Tract Infection, Respiratory Syncytial Virus Infections
Utilization and Compliance of Respiratory Syncytial Virus Monoclonal Antibody Therapy
The purpose of this study is to determine the utilization patterns and compliance rates of palivizumab, which is a monoclonal antibody therapy used to prevent respiratory syncytial virus infection.
- Trial name
- NCT00420966
- Where
- 2 sites in Canada
- Volunteers
- 25,003 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pleural Diseases, Infection
Impact of Respiratory Physiotherapy in the Management of Infectious Pleural Effusion
Chest physiotherapy (CP) facilitates the absorption of fluid in the pleural cavity and reduces the formation of fibrous adhesions in patients with pleural infection, allowing a faster clinical, functional and radiological…
- Trial name
- FISIOPLEURA (NCT02359383)
- Testing
- Chest physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital de Granollers
Lower Respiratory Tract Infection
The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
This is a Prospective, multi-center study enrolling adults subjects presented to the ED/Urgent care, with symptoms consistent with lower respiratory infection (LRTI).
- Trial name
- NCT05762302
- Testing
- MeMed BV test
- Where
- 10 sites in United States, Israel
- Volunteers
- 1,316 people
- Sponsor
- MeMed Diagnostics Ltd.
Lung Diseases, Lung Inflammation
Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery
The purpose of this study is to analyze the impact of the intravenous (IV) or paravertebral (PV) lidocaine administration during the intraoperative period of lung resection surgery on the appearance of postoperative…
- Conditions
- Lung Diseases, Lung Inflammation, Lung Injury, Acute, Postoperative Complications
- Trial name
- NCT03905837
- Testing
- Lidocaine, Remifentanil
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Francisco Andres de la Gala
COVID-19 Pandemic, Anesthesia
Intraoperative Lung Mechanics and Functional Evaluation in Post COVID-19 Thoracotomy Patients
At the end of 2019, cases of an unknown respiratory infection were reported in the city of Wuhan in China. It was determined that the cause of this infection was a new virus belonging to the coronavirus family, which was named…
- Conditions
- COVID-19 Pandemic, Anesthesia, Thoracic Diseases
- Trial name
- NCT05851807
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Rhinovirus
The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study
The goal of this study is to determine the burden of Rhinoviruses (RVs) as a cause of acute, severe, respiratory illnesses leading to hospitalization.
- Trial name
- NCT07342582
- Testing
- Nasal Swab Healthy Surveillance, Nasal Swab Sick Samples, Nasal Swab Hospitalized Cohort
- Where
- United States
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19
INFLUENCE OF HIGH FREQUENCY CHEST WALL OSCILLATION IN HOSPITALIZED PATIENTS WITH COVID-19 The purpose of this Interventional study is to investigate the effect of high frequency chest wall oscillation in hospitalized COVID-19…
- Trial name
- HFCWO IN COVID (NCT05705661)
- Testing
- HIGH FREQUENCY CHEST WALL OSCILLATION
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cairo University
SARS-CoV 2, End Stage Renal Failure on Dialysis
Serological Testing for COVID-19 (SARS-CoV-2) in ESKD
Starting in late 2019, the world is facing a pandemic with the SARS-CoV-2 virus. Patients with end-stage kidney disease and on treatment with renal replacement therapy are high risk patients, as they are unable to maximize social…
- Trial name
- NCT04378686
- Testing
- dialysis
- Where
- 3 sites in Belgium
- Volunteers
- 500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven