Clinical trials: Chest Pain
VATS, Kinesiophobia
Comparison of Early Postoperative Functional Capacity and Kinesiophobia in Patients Undergoing Thoracic Surgery Via Thoracotomy or VATS
This observational cross-sectional study aims to compare early postoperative functional capacity and kinesiophobia in patients undergoing thoracic surgery via thoracotomy or video-assisted thoracic surgery (VATS).
- Conditions
- VATS, Kinesiophobia, Thoracotomy, Thoracic Surgery
- Trial name
- NCT07647822
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
Cardiovascular Diseases, Medical Device
Validation of PMcardio AI-assisted Clinical Assistant in Primary Care
This study aimed to analyze and investigate whether the use of the PMcardio clinical assistant leads to a more efficient patient management in primary care and more accessible specialised care compared to usual standards of care…
- Conditions
- Cardiovascular Diseases, Medical Device, Primary Health Care, Electrocardiogram
- Trial name
- PMCARDIO-PT1 (NCT05329246)
- Testing
- AI-assisted Clinical Assistant PMcardio
- Where
- 56 sites in Slovakia
- Volunteers
- 836 people
- Sponsor
- Powerful Medical
Chest Pain, Symptomatic Ischemic Equivalent
Stress Echo Ultrasound Contrast in an Urban Safety Net Hospital to Refine Ischemia Evaluation
The current study is designed to have broad generalizability and inform a potential shift toward greater utilization of stress echocardiography with UCA.
- Trial name
- SECURE (NCT01572220)
- Testing
- UCA stress echocardiography or myocardial SPECT
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Denver Health and Hospital Authority
Ischemic Heart Disease, Angina, Stable
Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe Lesions
PROPHET-FFR is a single center ambispective registry aiming to explore the impact of post-revascularization functional assessment on later outcomes.
- Conditions
- Ischemic Heart Disease, Angina, Stable, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction
- Trial name
- PROPHET-FFR (NCT05056662)
- Testing
- Invasive functional evaluation with either Pd/Pa, FFR, iFR or contrast FFR
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Catholic University of the Sacred Heart
Forward Head Posture, Thoracic Hypomobility
Supplemental Effects of ELDOA in Addition to Thoracic Manipulation on Upper Back Pain, Thoracic Kyphosis and Forward Head Posture in Thoracic Hypomobility
The purpose of this study is to determine the supplemental effects of ELDOA in addition to thoracic manipulation on upper back pain, thoracic kyphosis and forward head posture in thoracic hypomobility.
- Conditions
- Forward Head Posture, Thoracic Hypomobility, Upper Back Pain
- Trial name
- ELDOA-MAN (NCT06455423)
- Testing
- Thoracic Manipulation, Chin tuck in exercises, Thoracic Extension Exercise
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Non-specific Low Back Pain, Low Back Pain
Correlation Between Hip Mobility and Thoracic Flexion in Patients With Non-Specific Low Back Pain
This cross-sectional observational study investigates the relationship between hip joint mobility and thoracic flexion in patients diagnosed with non-specific low back pain.
- Conditions
- Non-specific Low Back Pain, Low Back Pain, Musculoskeletal Disorders, Thoracic Spine Dysfunction
- Trial name
- NCT07429279
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Deraya University
Thoracic Surgery
Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS
The purpose of this study, is to investigate the effectiveness of ultrasound-guided rhombic intercostal nerve block for postoperative pain control in thoracoscopic pulmonary resection with bupivacaine liposomes versus bupivacaine…
- Trial name
- NCT06392191
- Testing
- Rhombic intercostal nerve block(Received liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20 ml), Rhombic intercostal nerve block(Receive standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg.)
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Coronary Artery Disease, Chest Pain
Artificial Intelligence Stress Echo (FINESSE) Project
The goal of this observational study is to learn whether combining stress echocardiography (stress echo) results with routine clinical information can better predict important heart outcomes in adults (18+) with chest pain who…
- Conditions
- Coronary Artery Disease, Chest Pain, Myocardial Ischemia, Angina Pectoris
- Trial name
- FINESSE (NCT07432620)
- Testing
- Dobutamine Stress Echocardiography
- Where
- United Kingdom
- Volunteers
- 2,281 people
- Sponsor
- Milton Keynes University Hospital NHS Foundation Trust
Atherosclerosis, Stroke
Vascular Inflammation Imaging Using Somatostatin Receptor Positron Emission Tomography
This VISION study aims to investigate the role of inflammation in atherosclerosis using 68Ga- DOTATATE PET, and to validate 68Ga-DOTATATE PET imaging for the detection and quantification of vascular inflammation in the aorta…
- Conditions
- Atherosclerosis, Stroke, Transient Ischemic Attack, Chronic Stable Angina
- Trial name
- VISION (NCT02021188)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Cambridge
Postoperative Pain, Acute, Postoperative Pain, Chronic
Application of Non-invasive Neurophysiological Methods in Predicting and Evaluating Postoperative Pain in Adult Patients Undergoing Major Thoracic Surgery
The primary aim of this study is to explore the relationship between alpha electroencephalographic oscillations, particularly Peak Alpha Frequency (PAF), pupillometry, intraoperative Nociception Level (NOL) and postoperative pain…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Postoperative Pain After Thoracic Surgery
- Trial name
- NCT06731010
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Ischemic Heart Disease, Non STEMI
Coronary Computed Tomography Versus Invasive Angiography for Non-ST Elevation Acute Coronary Syndrome
Coronary computed tomography angiography (CCTA) is a widely accepted initial diagnostic test for individuals suspected of having chronic coronary syndromes.
- Conditions
- Ischemic Heart Disease, Non STEMI, Angina Pectoris, Unstable, Coronary Disease
- Trial name
- TRACTION (NCT06101862)
- Testing
- CCTA, Conventional ICA, Team-based interventional triage
- Where
- 6 sites in Denmark
- Volunteers
- 2,300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Stable Angina, Coronary Artery Disease
Impact of Rotational Atherectomy on Coronary Microcirculation
The purpose of this observational study is to compare the impact of rotational atherectomy to conventional stenting and to investigate how it may affect coronary microcirculation in patients with calcified coronary artery lesions…
- Trial name
- MICRO-ROTA (NCT05771961)
- Testing
- coronary pressure/temperature sensor-tipped guidewire, Angiography-derived index of microcirculatory resistance (IMRangio)
- Where
- Lithuania
- Volunteers
- 300 people
- Sponsor
- Lithuanian University of Health Sciences
Rib Fractures, Rib Fracture Multiple
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death.
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib; Fracture, With Flail Chest, Pain
- Trial name
- UNPIN (NCT05865327)
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Neck Pain
Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine
Neck pain continues to be a prevalent condition in our society. Manual therapy (hands on techniques for the treatment of neck pain is an intervention commonly implemented in clinical practice.
- Trial name
- NCT01318720
- Testing
- Manual Therapy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Masefield and Cavallaro Physical Therapy
Lung Cancer
A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil
The goal of this clinical research study is to compare armodafinil and minocycline when given alone or in combination to learn which is better for controlling symptoms, such as the side effects of chemoradiation, when given to…
- Trial name
- NCT01317550
- Testing
- Armodafinil, Minocycline, Questionnaires
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- M.D. Anderson Cancer Center
Posture, Kyphosis
Effects of Telerehabilitation-based Motor Imagery and Exercise Combination in Individuals With Postural Kyphosis: A Randomized Controlled Trial
Objective: Kyphosis is one of the most common postural problems. It is defined as a thoracic curvature that exceeds normal limits.
- Conditions
- Posture, Kyphosis, Muscle Cramps, Thoracic Vertebrae
- Trial name
- NCT07122791
- Testing
- Home Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Lung Nodules, Lung Cancer
The Impact of Thoracic Paravertebral Nerve Block At Different Positions on Pain Relief in Patients Undergoing Single-Port Thoracoscopic Partial Lung Resection
Thoracic surgery is widely recognized as one of the most painful surgical procedures. Compared to open thoracotomy, video-assisted thoracoscopic surgery (VATS) offers similar therapeutic outcomes with less invasiveness…
- Trial name
- NCT06789276
- Testing
- Supine position, lateral decubitus position
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Acute Myocardial Infarction, Acute Coronary Syndrome
Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
- Conditions
- Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention
- Trial name
- iCARE (NCT04938661)
- Testing
- Center-Based Cardiac Rehab, mHealth, Home-Based Cardiac Rehab
- Where
- 2 sites in United States
- Volunteers
- 206 people
- Sponsor
- Mayo Clinic
Coronary Artery Diseases, Myocardial Infarction
The Efficacy of Influenza Vaccination in Patients With Coronary Artery Diseases
This study wishes to understand: 1. whether vaccination against influenza in coronary artery disease (myocardial infarction and stable angina) patients is as effective as it is in healthy subjects; 2.
- Conditions
- Coronary Artery Diseases, Myocardial Infarction, Stable Angina
- Trial name
- NCT00607217
- Testing
- influenza vaccine
- Where
- Iran
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences