Clinical trials: Chest Pains
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Abdominal Pain, Chest Pain
Anchoring Patients Pain Scores in the Emergency Department
The proposed research will be a prospective, observational study to test the hypothesis that anchoring will affect verbal pain scores in the emergency department.
- Conditions
- Abdominal Pain, Chest Pain, Headache, Joint Pain
- Trial name
- NCT04717518
- Testing
- Measurement of Pain
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Pain, Postoperative, Lung Cancer
Postoperative Pain Control With Lipossomic Extended Release Bupivacaine
Randomized trial of intraoperative intercostal block with bupivacaine with epinephrine compared to lipossomal extended release bupivacaine.
- Trial name
- NCT03560362
- Testing
- Bupivacaine liposome, Bupivacaine / Epinephrine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Tennessee
Acute Myocardial Infarction, Unstable Angina
Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease
Preclinical studies have demonstrated that high mechanical index (MI) impulses from a diagnostic ultrasound (DUS) transducer during an intravenous microbubble infusion (sonothrombolysis) can restore epicardial and microvascular…
- Trial name
- HUBBLE-I (NCT04732091)
- Testing
- Therapeutic ultrasound with 20 usec
- Where
- 2 sites in United States, Brazil
- Volunteers
- 540 people
- Sponsor
- University of Sao Paulo General Hospital
Lung Cancer
Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer
The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.
- Trial name
- NCT05478460
- Testing
- Hookwire localization
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Fudan University
Chest Pain, ST Elevation Myocardial Infarction
The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.
Patient delay in seeking medical attendance for symptoms of acute ST elevation myocardial infarction (STEMI) is the major obstacle to reduce the current mortality from acute coronary syndromes.
- Trial name
- RELF IIa (NCT02983396)
- Testing
- Diagnostic accuracy of Mini Relf Device
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
Nerve Block, Nephrectomy, Analgesia
QLB Versus PVB for Acute Pain and Quality of Recovery After Laparoscopic Partial Nephrectomy
This trial is a prospective, randomized, single-center, open-label, parallel-arm, blinded-analysis trial, the objective of which is to evaluate the effect of transmuscular quadratus lumborum block (TMQLB) in the pain relief and…
- Trial name
- NCT03975296
- Testing
- preoperative single-shot TMQLB, preoperative single-shot TPVB, patient controlled intravenous analgesia(PCIA)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Cui Xulei
Endothelial Dysfunction, Atherosclerosis
Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries
The investigators are hoping to discover the cause of chest pain in patients with a normal coronary arteriogram. For patients with chest pain coronary angiography is the standard method by which the blood vessels of the heart can…
- Conditions
- Endothelial Dysfunction, Atherosclerosis, Inflammation, Myocardial Ischemia
- Trial name
- ACOVA (NCT01162824)
- Testing
- Acetylcholine, Adenosine
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- St George's Healthcare NHS Trust
Chest Pain
Chest Pain Triage at ED
CECIDOC is a prospective, monocentric and observational study comparing the diagnostic performance of ECG-base triage to a combination of ECG and cardiovascular risk factors for chest pain triage at ED.
- Trial name
- CECIDOC (NCT03913767)
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Université Catholique de Louvain
Acute Myocardial Infarction, Chest Pain
Evaluation of Serial Troponin and Cardiac Multimarkers at the Point of Care in the Emergency Department
This is a multi-center study to assess the diagnostic accuracy of the Troponin I assay in the Biosite Triage Cardio3 Panel at the point-of-care (POC) in adults presenting to the emergency department with possible acute myocardial…
- Conditions
- Acute Myocardial Infarction, Chest Pain, Acute Coronary Syndrome
- Trial name
- ESTIMATE (NCT00907231)
- Where
- 6 sites in United States
- Sponsor
- Abbott RDx Cardiometabolic
Stable Angina
CYP2C19 Gene Alteration and Thienopyridine Resistance in Percutaneous Coronary Intervention Study
Dual antiplatelet therapy with aspirin and thienopyridines decreases the rate of stent thrombosis in patients undergoing percutaneous coronary intervention (PCI).
- Trial name
- CALDERA-PCI (NCT00876512)
- Where
- Japan
- Volunteers
- 104 people
- Sponsor
- Kumamoto University
Chronic Stable Angina, Coronary Artery Disease
Safety of Amiodarone and Ranolazine Together in Patients With Angina
Ranolazine is an effective and remarkably safe agent for the treatment of patients with chronic stable angina, but its inhibition of voltage gated potassium channels and electrocardiogram (EKG) corrected QT (QTc) prolongation…
- Conditions
- Chronic Stable Angina, Coronary Artery Disease, Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- SARA (NCT01558830)
- Testing
- ranolazine
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cardiovascular Consultants of Nevada
Acute Coronary Syndrome, Angina Pectoris, Unstable
Incremental Value of Point of Care H-FABP Testing in Primary Care Patients Suspected of Acute Coronary Syndrome
Rationale: Thoracic complaints, possibly due to a cardiac ischemic cause are a diagnostic challenge in general practice. When an underlying ischemic cardiac condition (AMI (acute myocardial infarction), UAP (unstable angina…
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Unstable, Angina Pectoris, Stable, Thoracic Diseases
- Trial name
- RAPIDA (NCT01826994)
- Testing
- heart type fatty acid binding protein testing
- Where
- 7 sites in Belgium, Netherlands
- Volunteers
- 303 people
- Sponsor
- Maastricht University Medical Center
Lidocaine, Analgesia
Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection.
- Conditions
- Lidocaine, Analgesia, Pain, Postoperative, Thoracic Surgery
- Trial name
- NCT05901389
- Testing
- Lidocaine, Sufentanil
- Where
- China
- Volunteers
- 451 people
- Sponsor
- Qilu Hospital of Shandong University
Myocardial Infarction, Angina, Unstable
Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
Coronary artery disease (CAD) is caused by a narrowing of the blood vessels that supply blood and oxygen to the heart. Balloon angioplasty and stent placement are two treatment options for people with reduced heart function…
- Conditions
- Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
- Trial name
- NCT00692991
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Angina Pectoris, Cardiovascular Diseases
Platelet-Inhibitor Drug Trial in Coronary Angioplasty
To determine the effectiveness of dipyridamole and aspirin in prevention of restenosis of the dilated lesion in patients who had undergone percutaneous transluminal coronary angioplasty (PTCA).
- Conditions
- Angina Pectoris, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000510
- Testing
- aspirin, dipyridamole, angioplasty, transluminal, percutaneous coronary
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Frozen Shoulder
Cervical and Thoracic Mobility Training in Patients With Adhesive Capsulitis
The aim of this study is to investigate the effect of cervical and thoracic mobilization training on posture, shoulder pain, joint range of motion and shoulder function in patients with adhesive capsulitis.
- Trial name
- NCT07433478
- Testing
- Convantional rehabilitation, Cervical and Thoracic Mobilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zonguldak Bulent Ecevit University
Acute Coronary Disease, Angina Unstable
Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionS
The purpose of this study is to evaluate whether a higher dosage of clopidogrel with aspirin (two doses) will decrease the risk of ischemic complications (cardiac death (CV death), myocardial infarction (MI), stroke) after a…
- Trial name
- CURRENT/OASIS7 (NCT00335452)
- Testing
- Clopidogrel, acetylsalicyclic acid (ASA)
- Where
- 38 sites in United States, Argentina and 36 more
- Volunteers
- 25,086 people
- Sponsor
- Sanofi
Postoperative Pain
Continuous Thoracic Paravertebral Analgesia for Video-assisted Thoracoscopic Surgery
This study is designed to assess: The impact of continuous thoracic paravertebral nerve blockade compared to intercostal nerve blockade on the intensity of postoperative pain following VATS in subjects having a Patient Controlled…
- Trial name
- NCT02670759
- Testing
- Continuous infusion of bupivacaine, Single dose of bupivacaine
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Bone Metastases
ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain
A study to evaluate the safety and initial effectiveness of the ExAblate 2100 Conformal Bone System in the treatment of pain resulting from metastatic bone tumors.
- Trial name
- NCT00981578
- Testing
- ExAblate 2100
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- InSightec
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