Clinical trials: Chest Pains
Chest Pain
A Comparison of the TIMI, GRACE, HEART and HEARTSIL Scores
Chest pain is one of the most common reasons for emergency admission. Chest pain can be caused by many cardiac and noncardiac causes. Acute Coronary Syndrome (ACS) is one of the most im-portant of these etiologies.
- Trial name
- NCT04661722
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Konya Meram State Hospital
Paresthesia, Dysesthesia
Sensory Mapping Following Video-assisted Thoracic Surgery
This is a prospective observational cohort study on changes in sensory mapping.
- Conditions
- Paresthesia, Dysesthesia, Pain
- Trial name
- NCT01375283
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Microvascular Angina
Non-invasive Diagnosis of Coronary Microvascular Disease: Pilot Study
40% of patients presenting with stable chest pain (angina) have no significant blockage of the main heart arteries. Identifying why these patients have symptoms will mean better treatment options can be developed.
- Trial name
- NCT06070662
- Testing
- Coronary microvascular disease testing during coronary angiography, Cardiac magnetic resonance scan including exercise, Additional analysis of already acquired CT scan
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Leicester
Rib Fracture
Ibuprofen Versus Dexketoprofen in Rib Fractures
The purpose of this study is to compare the pain-relieving effects of two different nonsteroidal anti-inflammatory drugs (NSAIDs), intravenous ibuprofen and intravenous dexketoprofen, in adults who present to the emergency…
- Trial name
- NCT07859631
- Testing
- Ibuprofen 800 mg, Dexketoprofen 50 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Ankara City Hospital Bilkent
Stable Angina, Unstable Angina
Assessment of Diagonal Branch Territory
This study was performed to investigate the anatomical attributes that determine myocardial territory of diagonal branches and to develop a prediction model for clinically relevant branches using myocardial perfusion imaging…
- Trial name
- NCT03935542
- Where
- South Korea
- Volunteers
- 355 people
- Sponsor
- Bon-Kwon Koo
Pain, Postoperative
Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Introduction Adult living related donor hepatectomy is associated with pain due to the sub-costal j-shaped incision, rib retraction using Thompson retractor, and diaphragm irritation1.
- Trial name
- NCT04151511
- Testing
- Continuous Erector Spinae Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa Clinical Research Center
Restenosis, Stable Angina Pectoris
Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 4
The purpose of the study is to determine whether scoring balloon (SCB) plus paclitaxel-coated balloon (PCB) is superior to PCB alone for the treatment of restenosis within "limus"-eluting stents (LES)
- Conditions
- Restenosis, Stable Angina Pectoris, Acute Coronary Syndrome
- Trial name
- ISAR-DESIRE 4 (NCT01632371)
- Testing
- Paclitaxel Eluting Balloon + Scoring Balloon, Paclitaxel Eluting Balloon
- Where
- 2 sites in Germany
- Volunteers
- 252 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Acute Coronary Syndrome, Acute Myocardial Infarction
Comparison Between Ticagrelor Versus Very Low Dose Rivaroxaban With Clopidogrel
A total of 50 participants diagnosed with ACS (group A ticagrelor 180mg/d, n=25), group B (clopidogrel 75mg + rivaroxaban 5mg/ d, n=25)) were consecutively enrolled and treated with study drugs on top of aspirin (100mg/d) for 1…
- Conditions
- Acute Coronary Syndrome, Acute Myocardial Infarction, Unstable Angina
- Trial name
- NCT03481257
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Diseases
NITRATE-OCT-CIN (Sub-Study of NITRATE-OCT)
The NITRATE-OCT:- Contrast Nephropathy Sub-study is a proof-of concept single center, randomized, clinical trial designed to ascertain whether a dietary NO3- approach might prove useful adjunctive therapy improving renal function…
- Trial name
- NIT-OCT-CIN (NCT05544981)
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Queen Mary University of London
Hypertrophic Cardiomyopathy
Coronary Sinus Reducer Objective Impact on SymptoMs, Ischaemia and miCrovascular Resistance in Non-obstructive Hypertrophic CardioMyopathy
Hypertrophic cardiomyopathy (HCM) is a common heart condition in which the heart muscle becomes abnormally thick. In non-obstructive HCM, blood flow out of the heart is not blocked, but many patients still experience chest pain…
- Trial name
- COSMIC-HCM (NCT07865364)
- Testing
- Coronary sinus reducer
- Where
- 8 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
Coronary Syndrome
Multi-omics Study of Young Adults Coronary Syndrome Patients
With the rapid development of China's economy, changes in diet structure, lifestyle and excessive mental pressure have led to a younger trend in the incidence of ACUTE coronary syndrome, and the mortality rate has been on the…
- Trial name
- Young-COSMOS (NCT04864457)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shenzhen People's Hospital
Thromboembolism
Michelangelo - Oasis 5
Study Objectives PRIMARY OBJECTIVE: To evaluate whether fondaparinux is at least as effective as or superior to enoxaparin in preventing death, myocardial infarction or refactory ischemia up to Day 9 in the acute treatment of…
- Trial name
- NCT00139815
- Testing
- Fondaparinux, enoxaparin
- Volunteers
- 20,078 people
- Sponsor
- GlaxoSmithKline
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Chest Pain, Coronary Occlusion
Advanced Cardiovascular Imaging Consortium
The ACIC is a Collaborative Quality Improvement (CQI) program involving the collection of data related to: indications for Coronary Computed Tomography (CCTA), patient health characteristics, acquisition techniques of CCTA scans…
- Conditions
- Chest Pain, Coronary Occlusion, Coronary Artery Disease
- Trial name
- ACIC (NCT00640068)
- Where
- 50 sites in United States
- Volunteers
- 42,926 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Pain, Postoperative
pMDT in Thoracic Surgery--The Process Implementation Stage
The risk of acute and chronic pain after thoracic surgery is high. The multi-disciplinary postoperative pain management strategy is the best way to control postoperative pain in thoracic surgery.
- Trial name
- NCT03761550
- Testing
- pMDT(Process Implementation)
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Peking University People's Hospital
Coronary Artery Disease, Stable Angina
Comparison of Left and Right Transradial Approach for CAG and PCI
This trial will compare the procedural success rate between right and left radial approach in patients undergoing coronary angiography and coronary intervention.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction
- Trial name
- COMPARE-Rad (NCT03389503)
- Testing
- Radial approach
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Wonju Severance Christian Hospital
Chest Pain Syndrome
Comprehensive Cardiothoracic Dual Source CT for the Early Triage of Patients With Acute Chest Pain
The purpose of this research is to determine the efficiency of a single dual source computed tomography (CT-DSCT) protocol to establish or exclude acute coronary syndrome (ACS), pulmonary embolism (PE) or aortic dissection (AD)…
- Trial name
- CAPTURE (NCT01067456)
- Testing
- Comprehensive Cardiothoracic CT arm
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Massachusetts General Hospital
Ischemic Heart Disease
Registry of Comprehensive Imaging and Physiological Evaluation of Deferred Lesions Based on FFR
1. To compare the risk of atherosclerotic lesion progression and subsequent patient-oriented composite outcomes (all-cause mortality, any MI, or any Ischemia-driven repeat revascularization) between deferred lesions with or…
- Trial name
- IMPACT-FFR (NCT03030495)
- Testing
- Comprehensive physiologic evaluation, Intravascular imaging devices
- Where
- 4 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Samsung Medical Center
Lung Cancer
Predictors of Acute and Persistent Postoperative Pain in Lung Cancer Surgery
The aim of this observational study is to investigate if preoperative quantitative sensory testing, anxiety and depression symptoms, and biological markers are associated with the risk of developing acute and chronic…
- Trial name
- NCT05599386
- Testing
- Preoperative test
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Jannie Bisgaard Stæhr
Angina Pectoris
Myocardial Ischemia After Coronary Sinus Reduction Stent Implantation
Chronic angina pectoris refractory to medical and revascularization therapies is a disabling medical condition and a major public health problem. Patients with refractory angina have limited treatment options.
- Trial name
- MICS-Reduce (NCT06033495)
- Testing
- Coronary sinus reduction stent
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
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