Clinical trials: Chest Pains
Coronary Artery Disease, Asthma
Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR)
The goal of this research is to determine the utility of Regadenoson (Lexiscan)for use as an imaging agent with cardiac MR. If found useful, it will help us establish a protocol for regadenoson stress MR perfusion (Regadenoson…
- Conditions
- Coronary Artery Disease, Asthma, Chronic Obstructive Pulmonary Disease (COPD), Angina
- Trial name
- NCT00763035
- Testing
- Regadenoson, Dobutamine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
MECHANICAL BACK PAIN, Sleep Quality
Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality
Investigation Of The Effects Of Thoracic Manipulation And Classical Massage On Pain Flexibility And Sleep Quality In Patients With Mechanical Back Pain
- Trial name
- NCT07518732
- Testing
- Classical Massage, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ayşe BAŞAYAN
Unstable Angina
PROTECT-TIMI 30 Trial
The primary purpose of this study was to compare the efficacy and safety of bivalirudin to eptifibatide (with or without unfractionated heparin or enoxaparin)given to subjects at high risk for heart attack and other…
- Trial name
- NCT00250471
- Testing
- Percutaneous Coronary Intervention (PCI)
- Volunteers
- 900 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Pain, Postoperative, Pain, Chest
Pharmacokinetic Profile and Dermatomal Coverage of the Erector Spinae Plane Block
The goals of this study are as follows: 1. to confirm the safe dosing of ropivacaine for the erector spinae plane block 2. develop a pharmacokinetic profile of the erector spinae plane block, which will help demonstrate how…
- Trial name
- NCT03874806
- Testing
- Ropivacaine 0.25%-NaCl 0.9% Injectable Solution, Ropivacaine 0.2%-NaCl 0.9% Injectable Solution
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Coronary Artery Disease, Coronary Heart Disease
Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent
The purpose of this multicenter, randomized, open label, parallel arm study whether the newest 3rd generation stent - Orsiro hybrid sirolimus-eluting stent is noninferior to the newest 2nd generation stent - Resolute Integrity…
- Conditions
- Coronary Artery Disease, Coronary Heart Disease, Stable Angina, Unstable Angina
- Trial name
- ORIENT (NCT01826552)
- Testing
- Osiro Hybrid Drug-Eluting Stent, Resolute Integrity
- Where
- 8 sites in South Korea
- Volunteers
- 372 people
- Sponsor
- Seoul National University Bundang Hospital
Thoracic Anesthesia, Nerve Block
The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia.
- Conditions
- Thoracic Anesthesia, Nerve Block, Pain, Acute
- Trial name
- NCT04829409
- Testing
- Paravertebral block, ESP block, MTP block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Functional Chest Pain
Home Hypnotherapy for Refractory Functional Chest Pain: A Pilot Study
The primary aim is to develop and test the feasibility of a standardized digital audio home-hypnotherapy (HHT) program for patients with refractory functional chest pain (FCP). The secondary aims of this study are: 1.
- Trial name
- NCT01284179
- Testing
- Home Hypnotherapy, Educational
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Thoracotomy, Erector Spinae Plane Block
Efficacy of Ipsilateral High Thoracic Ultrasound-guided Erector Spinae Plane Block in Thoracic Cancer Surgeries
To evaluate the effectiveness of ultrasound guided Erector Spinae Plane Block (ESPB) in controlling post thoracotomy ipsilateral shoulder pain.
- Conditions
- Thoracotomy, Erector Spinae Plane Block, Thoracic Cancer, Shoulder Pain
- Trial name
- NCT05238688
- Testing
- Thoracic Epidural Analgesia (TEA) group, Thoracic Epidural Analgesia and Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Chest Pain, Nonmalignant Condition
Providing Patient Information and CT Examination Results
Chest pain is a common cause of visits in the Emergency Room and General Practice, and is most commonly connected as a symptom of coronary disease, as for instance angina pectoris and acute myocardial infarct.
- Trial name
- INFOCT (NCT03781661)
- Testing
- Extended information
- Where
- Norway
- Volunteers
- 92 people
- Sponsor
- Haukeland University Hospital
Coronary Heart Disease, Stable Angina Pectoris
Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation
The objective of this study is a comparative evaluation of Orsiro stent and of Resolute Integrity stent in terms of the extent of neointima formation at 4 months after implantation using optical coherence tomography (OCT).
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- Healing (NCT04465669)
- Testing
- Orsiro stents, Resolute Integrity® stents
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Nonsmall Cell Lung Cancer Cellular Diagnosis
Minimally Invasive or Open Surgery for Lung Cancer: Pain, Quality of Life and Economics.
Is thoracoscopic surgery better than traditional open surgery for lung cancer? Video assisted thoracoscopic surgery for lung cancer (VATS) is presumed to be less traumatic than traditional open surgery for lung cancer but this…
- Trial name
- PLEACE (NCT01278888)
- Testing
- Anterolateral thoracotomy, Posterolateral thoracotomy, VATS
- Where
- Denmark
- Volunteers
- 294 people
- Sponsor
- Peter B Licht
Ischemic Heart Disease, Coronary Artery Disease
Evaluating Myocardial Ischemia in Chest Pain Using Exercise CMR
Ischemic Heart Disease (IHD) is a condition of recurring chest pain or discomfort that occurs when a part of the heart is not receiving sufficient blood flow.
- Conditions
- Ischemic Heart Disease, Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia
- Trial name
- EMPIRE (NCT03217227)
- Testing
- Cardiovascular Magnetic Resonance Imaging with Exercise Bike, Cardiac Catheterization, Retinal Photography (Optional)
- Where
- 2 sites in Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Acute Coronary Syndromes, STEMI
Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome
This is a prospective, open-label, multicenter, randomized, phase IV clinical trial designed to evaluate the safety and efficacy of early aspirin discontinuation followed by potent P2Y12 inhibitor monotherapy after intravascular…
- Conditions
- Acute Coronary Syndromes, STEMI, NSTEMI, Unstable Angina
- Trial name
- SAPT-ACS (NCT07684742)
- Testing
- Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy
- Where
- South Korea
- Volunteers
- 1,900 people
- Sponsor
- Gyeongsang National University Hospital
Heart Diseases, Cardiovascular Diseases
Acute Cardiac Ischemia in Women in the ACI/TIPI Trial
To conduct a series of five inter-related studies on acute cardiac ischemia (ACI) in women.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Angina Pectoris, Myocardial Ischemia
- Trial name
- NCT00005701
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chest Pain
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
The goal of this study is to determine if rapid outpatient evaluation vs hospitalization management is the best strategy (based on patient-centered measures and safe, equitable, and efficient resource use) for evaluating patients…
- Trial name
- CARE-CP (NCT05897632)
- Testing
- Outpatient Evaluation, Hospitalization Evaluation
- Where
- 3 sites in United States
- Volunteers
- 502 people
- Sponsor
- Wake Forest University Health Sciences
Cardiovascular Diseases, Coronary Disease
Multicenter Study of Silent Myocardial Ischemia (MSSMI)
To determine if silent myocardial ischemia was associated with an increased risk of cardiac mortality and morbidity during a one to three year follow-up in patients with coronary heart disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Myocardial Ischemia, Heart Diseases
- Trial name
- NCT00005216
- Sponsor
- University of Rochester
Refractory Angina Pectoris
Effect of Daily Remote Ischemic Conditioning on the Life Quality of Refractory Angina Pectoris Patients
The purpose is to test whether daily ischemic conditioning of the arms over 30 days could reduce the frequency and severity of angina pectoris and improve the life quality of refractory angina pectoris patients.
- Trial name
- D-RIC-RAP (NCT02499250)
- Testing
- remote ischemic conditioning (TDFT-12-A2), Optimal medical treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Navy General Hospital, Beijing
Rib Fractures, Nerve Block
Erector Spinae Plane Block for Acute Pain Management in the Emergency Department
Rib fractures are a common cause of respiratory distress in trauma patients as poor pain control and subsequent hypoventilation commonly results in lung tissue collapse (atelectasis).
- Trial name
- NCT03590782
- Testing
- Erector Spinae Block
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Sickle Cell Disease
A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest Syndrome
Sickle cell disease is a genetic red blood cell disorder characterized by vaso-occlusion from sickling of red blood cells, that can lead to pain or organ complications such as acute chest syndrome.
- Trial name
- NCT02697240
- Testing
- Intravenous citrulline
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Mississippi Medical Center
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
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