Clinical trials: Chest Pains
Video Assisted Thoracic Surgery (VATS), Pain Management
QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS
Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes [1-3].
- Trial name
- NCT04990713
- Testing
- Serratus Plane Block (Local Anesthetic) and Intercostal Block (Local Anesthetic)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Coronary Syndrome, Angina Pectoris
Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)
The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity.
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Angina, Unstable, Myocardial Infarction
- Trial name
- BIO-RESORT (NCT01674803)
- Testing
- Orsiro, Synergy, Resolute Integrity
- Where
- Netherlands
- Volunteers
- 3,514 people
- Sponsor
- Foundation of Cardiovascular Research and Education Enschede
Coronary Artery Disease
Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Binodenoson (an experimental drug) and adenosine (an FDA-approved drug that is currently used by doctors) are used to increase blood flow to the heart just like when a person exercises on a treadmill.
- Trial name
- VISION-305 (NCT00944970)
- Testing
- binodenoson, adenosine
- Volunteers
- 578 people
- Sponsor
- Pfizer
Angina, Coronary Occlusion
XIENCE PRIME Japan Post-Marketing Surveillance (PMS)
The objectives of the PMS are to observe the frequency, type, and degree of device deficiency to assure the safety of the new medical device (XIENCE PRIME) as well as to collect information on evaluation of the efficacy and…
- Conditions
- Angina, Coronary Occlusion, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT01721096
- Testing
- XIENCE PRIME - Long Length (LL), XIENCE PRIME - Core Size
- Where
- Japan
- Volunteers
- 536 people
- Sponsor
- Abbott Medical Devices
Rib Fractures, Rib Fracture Multiple
Ketamine vs Lidocaine in Traumatic Rib Fractures
Rib fractures continue to be a common occurrence in trauma patients of all ages. Traumatic rib fractures can cause severe pain in patients and lead to shallow breathing and further complications such as the need for mechanical…
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib Trauma
- Trial name
- NCT04781673
- Testing
- Ketamine, Lidocaine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Brittany Hoyte
Coronary Artery Disease, Acute Myocardial Infarction
HOST - DAPT Duration According the Bleeding Risk
Dual antiplatelet agent therapy (DAPT) is essential in treating PCI patients. DAPT can minimize thrombotic adverse events that occur not only at the stented lesion, but along the whole coronary tree.
- Conditions
- Coronary Artery Disease, Acute Myocardial Infarction, Stable Angina
- Trial name
- HOST-BR (NCT05631769)
- Testing
- Dual antiplatelet agent duration
- Where
- South Korea
- Volunteers
- 4,900 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative, Lung Neoplasm
PATHOS Study Pain Assessment in Thoracic Oncologic Surgery
A randomized prospective trial to assess whether the use of loco regional anesthesia as adjuvant analgesic therapy is more effective of intravenous analgesia only.
- Trial name
- PATHOS (NCT03134729)
- Testing
- Ropivacaine for Serratus Plane Block (SPB)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Obstructive Sleep Apnea, Cardiac Syndrome X
A Prevalence Study of Obstructive Sleep Apnea in Subjects With Chest Pain, Positive Exercise Treadmill Test and Normal Coronary Angiogram
Cardiac syndrome X consists of a triad of chest pain, abnormal exercise stress testing and normal coronary angiogram, and is hypothesized to be related to endothelial dysfunction.
- Conditions
- Obstructive Sleep Apnea, Cardiac Syndrome X, Endothelial Dysfunction
- Trial name
- NCT01217346
- Testing
- no intervention is involved in this study
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Myocardial Infarction, Heart Failure, Systolic
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling.
- Conditions
- Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable
- Trial name
- NCT05933083
- Testing
- In-person cardiac rehabilitation, Telehealth cardiac rehabilitation
- Where
- 5 sites in United States
- Volunteers
- 516 people
- Sponsor
- University of California, San Francisco
Chronic Ischemic Heart Disease, Heart Failure
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Ischemic Cardiomyopathy
Phase I-II Clinical Trial-Safety and efficacy of umbilical cord derived mesenchymal stem cells (UC-MSCs) in patients with chronic heart ischemia cohort and perspective study.
- Conditions
- Chronic Ischemic Heart Disease, Heart Failure, Angina
- Trial name
- UCMSC-Heart (NCT02439541)
- Testing
- UCMSC group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Pain Management, Rib Fracture Multiple
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
The goal of this observational study is to learn about the long-term effects of the serratus anterior plane block (SAPB) in adult patients who suffered multiple unilateral anterolateral rib fractures within 24 hours of patient…
- Conditions
- Pain Management, Rib Fracture Multiple, Serratus Anterior Plane Block
- Trial name
- SAPB (NCT07032766)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Albert Einstein College of Medicine
Acute Coronary Syndrome
Clinical Governance of Patients With Acute Coronary Syndrome in Italy
This is a prospective, observational, multicenter study that enroll consecutive and all-comers patients hospitalized with a diagnosis of Acute Coronary Syndrome (ACS) at admission.
- Trial name
- NCT04255537
- Where
- 9 sites in Italy
- Volunteers
- 3,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Acute Myocardial Infarction, Coronary Syndrome
Antiplatelet Therapy Following Stent Implantation
Coronary artery stents, particularly drug-eluting stents (DES), are used in the majority of patients who undergo percutaneous coronary intervention (PCI) to improve symptoms in patients with obstructive coronary artery disease.
- Conditions
- Acute Myocardial Infarction, Coronary Syndrome, Angina, Unstable
- Trial name
- Anti-Clot (NCT02051361)
- Where
- Greece
- Volunteers
- 900 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Thoracic Outlet Syndrome
Effect of Osteopathic Technique on Respiratory Parameters and Pain in Thoracic Outlet Syndrome
Background: With regard to patients with thoracic outlet syndrome (GBS), it is important to improve inspiratory muscle strength and endurance, and pain perception in patients with TOS, so that patients are able to regain…
- Trial name
- NCT06446141
- Testing
- Osteopathic technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Heart Surgery, Thoracic Surgery
Evaluation of Virtual Reality for Reducing Opioid Use After Cardiac and Thoracic Surgery
This clinical trial aims to evaluate the efficacy of virtual reality (VR) as an adjunctive therapeutic method to reduce opioid consumption during the postoperative period of cardiac and thoracic surgeries.
- Conditions
- Heart Surgery, Thoracic Surgery, Opioid, Virtual Reality
- Trial name
- VR-USP (NCT07063394)
- Testing
- Interactive Virtual Reality, Passive Virtual Reality
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Filomena R B G Galas
Acute Post Operative Pain, Chronic Post Operative Pain
Combined Use of Naldebain® ER Injection and Precedex® After VATS
The goal of this clinical trial is to investigate the effects of combined use of Naldebain® ER Injection and Precedex® in patients received video-assisted thoracoscopic surgery.
- Conditions
- Acute Post Operative Pain, Chronic Post Operative Pain, Postoperative Complications
- Trial name
- NCT06176222
- Testing
- PRECEDEX INJ★ 2ML, Normal saline
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Compare the Response Rate of Atypical GERD After PPI Therapy
Comparison of the Efficiency of Two Different PPI Formula in Atypical GERD
Patients with atypical gastro-esophageal reflux disease (GERD), include cough, globus, and non-cardiac chest pain (NCCP) usually require more aggressive or double dose proton pump inhibitor (PPI) therapy than patients with typical…
- Trial name
- NCT03418337
- Testing
- dexilansoprazole (Dexilant 60 mg), lansoprazole (Takepron OD 30 mg)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Myocardial Infarction, Heart Attack
Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study
The primary aim of this study is to increase our understanding of care-seeking behavior surrounding heart attacks or acute coronary syndromes [ACS].
- Conditions
- Acute Myocardial Infarction, Heart Attack, Acute Coronary Syndrome, Unstable Angina
- Trial name
- NCT01407146
- Where
- United States
- Volunteers
- 2,381 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiac Arrythmias, Unstable Angina
CardioSenseSystem Compared Study Regarding Efficacy and Safety in the Monitoring of ECG
This is a prospective, controlled, comparative clinical trial of a new ECG monitoring system CardioSenseSystem prior CE marking.
- Conditions
- Cardiac Arrythmias, Unstable Angina, Heart Valve Disorders, Disorder of Aorta
- Trial name
- NCT03610529
- Testing
- CardioSenseSystem, Philips Intellivue
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Novosense AB
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Belgium Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01831336
- Where
- 8 sites in Belgium
- Volunteers
- 332 people
- Sponsor
- Biotronik Belgium NV
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