Clinical trials: Chest Pains
Acute Coronary Syndrome, Chest Pain
Comparison of Accelerated Diagnostic Pathways for Acute Chest Pain in Emergency Departments in the United Arab Emirates
This is a prospective four-site cohort study, which will accrue adults with symptoms concerning for acute coronary syndrome over a period of 12 months.
- Trial name
- NCT05532787
- Testing
- Application of acute chest pain risk stratification scores (HEART and EDACS)
- Where
- 5 sites in United Arab Emirates
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zayed Military Hospital
Chest Pain
ComParative Diagnostic Study Between Multislice Computed Tomography (MSCT) and Stress Echography in Coronarin Patients.
The aim of this study is to define the best prognostic strategy for patients presenting suspected acute CORONARY syndrome, between MSCT and stress echocardiography.
- Trial name
- PEPSI (NCT00709670)
- Testing
- MSCT and stress echocardiography
- Where
- France
- Volunteers
- 217 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Stenosis, Type2 Diabetes
Human Vasodilatory Effect of GLP-1
Comprehensive assessment of human vasodilatory effect of GLP-1 in forearm and coronary arteries
- Conditions
- Coronary Stenosis, Type2 Diabetes, Angina, Stable
- Trial name
- NCT03502083
- Testing
- GLP-1 (7-36)Amide
- Volunteers
- 11 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Stable or Unstable Angina Pectoris, Myocardial Ischemia
Efficiency of a New Therapy to Treat Stenosis of Coronary Vessels in Comparison With Two Already Admitted Therapies
The aim of the study is to examine the efficacy of Paclitaxel injection after a stent implantation in patients with stenosis in native coronary arteries to prevent restenosis in comparision with two admitted therapies.
- Trial name
- NCT00396929
- Testing
- local intracoronary dosis of Paclitaxel
- Where
- Germany
- Volunteers
- 204 people
- Sponsor
- University Hospital Tuebingen
Angina
Optical Coherence Tomography to Improve Clinical Outcomes During Coronary Angioplasty
Coronary artery stenting has evolved as an effective treatment for angina and involves stretching up narrowings within the heart arteries using a balloon (coronary angioplasty) before implanting a small metal scaffold (stent) to…
- Trial name
- NCT02065102
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Royal Infirmary of Edinburgh
Acute Coronary Syndrome
Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina
The purpose of this study is to determine if veliflapon (DG-031)can prevent a heart attack or stroke in African American patients with a history of unstable angina or myocardial infarction.
- Trial name
- NCT00353067
- Testing
- veliflapon (DG-031)
- Where
- 11 sites in United States
- Volunteers
- 3,450 people
- Sponsor
- deCODE genetics
Ischemic Heart Disease, Stable Angina
BioFreedom US IDE Feasibility Trial
The purpose of this study is to collect additional safety and effectiveness data for on the Biosensors BioFreedom™ BA9 Drug Coated Coronary Stent in patients with native, de novo coronary artery disease.
- Conditions
- Ischemic Heart Disease, Stable Angina, Unstable Angina, Silent Ischemia
- Trial name
- NCT02131142
- Testing
- BioFreedom drug coated coronary stent
- Where
- 13 sites in United States
- Volunteers
- 72 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease, Stable Angina Pectoris
A Comparative Evaluation of the Extent of Neointima Formation at 1 Month and 2 Months After Implantation Using OCT
The objective of this study is a comparative evaluation of BuMA Supreme™ stent and of Xience V/Prime stent in terms of the extent of neointima formation at 1 or 2 months after implanting in relatively high bleeding risk patients…
- Conditions
- Coronary Artery Disease, Stable Angina Pectoris, Unstable Angina Pectoris
- Trial name
- NCT02747329
- Testing
- BuMA Supreme™ stent, Xience V/Prime stent
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Ischemic Heart Disease, Coronary Microvascular Disease
MCG as a Noninvasive Diagnostic Strategy for Suspected INOCA (MICRO2)
A prospective, multicenter, observational, single-arm trial to validate CardioFlux MCG's ability to diagnose myocardial ischemia caused by coronary microvascular dysfunction in patients with suspected ischemia and confirmed no…
- Conditions
- Ischemic Heart Disease, Coronary Microvascular Disease, Angina, Myocardial Ischemia
- Trial name
- MICRO2 (NCT06212466)
- Testing
- CardioFlux
- Where
- 8 sites in United States
- Volunteers
- 136 people
- Sponsor
- Genetesis Inc.
Lung Cancer(Primary, Metastatic), Benign Lung Mass Requiring Operation
The Impact of Intraoperative Systemic Lidocaine Infusion on Chronic Postoperative Pain After Video-assisted Thoracic Surgery (VATS)
Systemic lidocaine infusion may improve the patients' chronic post surgical pain after video-assisted thoracic surgery
- Trial name
- NCT02006966
- Testing
- Systemic intravenous lidocaine infusion, Normal saline infusion
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Yonsei University
Shoulder Pain
Development of a Clinical Prediction Rule to Identify Patients With Shoulder Pain Likely to Benefit From Cervicothoracic Manipulation
The investigators seek to develop a clinical prediction rule (CPR) to identify patients with a primary complaint of shoulder pain who are likely to benefit from manual therapy to the neck and upper back regions.
- Trial name
- NCT00835302
- Testing
- Cervicothoracic manipulation
- Where
- 6 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Congestive Heart Failure, Angina
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Heart Disease
This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of congestive heart failure and angina
- Trial name
- NCT05147766
- Testing
- AlloRx
- Where
- 2 sites in Antigua and Barbuda, Argentina
- Volunteers
- 3 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Diabetes
A Study of Stress Heart Imaging in Patients With Diabetes at Risk for Coronary Disease.
The study is designed to see if stress heart imaging can be used as a screening exam in patients with diabetes and risk factors of developing of coronary artery disease and experiencing future cardiac events.
- Trial name
- NCT00162344
- Testing
- Technetium Tc99m Sestamibi
- Where
- 12 sites in United States, Canada
- Volunteers
- 205 people
- Sponsor
- Lantheus Medical Imaging
Coronary Artery Disease, Angina Pectoris
Understanding the Effect of Metformin on Corus CAD (or ASGES)
The study goal was to understand the effect of Metformin on Age/Sex/Gene Expression Score (ASGES) or Corus CAD (henceforth "Corus") in pre-diabetic patients who are medication naive.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- MET (NCT02440893)
- Testing
- Corus CAD (ASGES)
- Volunteers
- 37 people
- Sponsor
- CardioDx
Vasospastic Angina
Immunomodulatory Therapy & VSA
Vasospastic angina (VSA) is caused by brief spasms of the main coronary artery and its major branches, resulting in varying degrees of luminal occlusion.
- Trial name
- NCT06696807
- Testing
- glucocorticosteroids and/or intravenous immunoglobulin
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Dao Wen Wang
Non ST Segment Elevation Myocardial Infarction, Unstable Angina
Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation
This non-inferiority study aims at comparing Versa® to the reference enoxaparin (Clexane®, Sanofi-Aventis) in patients with high-risk unstable angina and NSTEMI.
- Trial name
- VECOR (NCT01356992)
- Testing
- Enoxaparin
- Where
- 5 sites in Brazil
- Volunteers
- 62 people
- Sponsor
- Eurofarma Laboratorios S.A.
Chest Trauma With Ribs Fractures
PEF-Block & Ribs Fractures
Rib fractures are frequent injuries found approximately in 10% severe trauma patient. Rib fractures were correlated in many studies with a higher morbidity and mortality.
- Trial name
- PEF (NCT03396692)
- Testing
- Intravenous morphine patient-controlled analgesia (PCA), Block of the posterior exo-thoracic fascia with Ropivacaine, Block of paravertebral space with Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Stable Angina
Treadmill Cardiovascular Safety Study of Erenumab (AMG 334)
A phase 2a, multicenter, randomized, double-blind, placebo-controlled study in adults with stable angina to evaluate the effect of erenumab (AMG 334) compared to placebo on exercise time during an exercise treadmill test.
- Trial name
- NCT02575833
- Testing
- Erenumab
- Where
- 33 sites in United States, Bulgaria and 8 more
- Volunteers
- 89 people
- Sponsor
- Amgen
Coronary Heart Disease, Stable Angina
Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris
This study is a randomized, double-blind, placebo-controlled, parallel clinical trial in Chinese population with stable angina pectoris.
- Trial name
- NCT04270071
- Testing
- Yangxin Shengmai, nitroglycerin tablets
- Volunteers
- 80 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Angina, Status Post PCI
Impact of Coronary Anatomy on Angina Relief in Patients Undergoing Coronary Revascularization
We hypothesize that Coronary Artery Disease (CAD) severity assessed by SYNTAX score is an independent predictor of recurrent or persistent angina following coronary revascularization.
- Conditions
- Angina, Status Post PCI, Status Post CABG
- Trial name
- NCT01665833
- Volunteers
- 4,000,000 people
- Sponsor
- North Texas Veterans Healthcare System
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