Clinical trials: Chest Pains
Coronary Heart Disease, Angina Pectoris
The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris
The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.
- Trial name
- NCT00737958
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Postoperative Pain
Modified Pectoral Nerve Block Vs Thoracic Erector Spinae Plane Block for Analgesia for Aesthetic Breast Surgeries
The aim of this study is to evaluate The Effectiveness of Ultrasound Guided Modified Pectoral Nerve Block (PECS II) versus Thoracic Erector Spinae Plane Block (ESPB) for postoperative Analgesia in cases of aesthetic breast…
- Trial name
- NCT06478654
- Testing
- Bilateral Modified Pectoral Nerve Block (PECS II)., Bilateral Thoracic Erector spinae plane block (ESPB).
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Coronary Syndrome, Chest Pain
Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain
The purpose of this study is to investigate the best way to evaluate patients with chest pain in the emergency department. It compares types of cardiac tests performed while receiving treatment in an observation unit.
- Trial name
- NCT00869245
- Testing
- OU - Cardiac MRI, OU - Conventional Care Testing
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Wake Forest University Health Sciences
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Discogenic Pain
Safety and Efficacy of PRP for Treatment of Disc Pain
This is a multi-center, randomized, controlled, double-blind clinical trial comparing hemocyte autograft (platelet rich plasma) to control injection (placebo) in subjects with reported cervical, thoracic or lumbar pain for at…
- Trial name
- NCT04064866
- Testing
- High yield pure PRP, ProPlaz PPC
- Where
- 7 sites in United States
- Volunteers
- 27 people
- Sponsor
- Neurological Associates of West Los Angeles
Lung Cancer
Study of Prevalence of Ipsilateral Shoulder Pain in Patients After Thoracic Surgeries
Thoracic surgeries are associated with significant operative trauma1. While thoracic epidural analgesia may help control the incisional component of the pain, an excruciating postthoracotomy.
- Trial name
- NCT03249766
- Testing
- Observational
- Where
- India
- Volunteers
- 370 people
- Sponsor
- Tata Memorial Hospital
Thoracic Surgery, Pneumonectomy
Personalized Postoperative Pain Management Following Thoracic Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Conditions
- Thoracic Surgery, Pneumonectomy, Lobectomy, Segmentectomy
- Trial name
- NCT05525923
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- OpalGenix, Inc
Stable Angina, Unstable Angina
Assessment of Diagonal Branch Territory
This study was performed to investigate the anatomical attributes that determine myocardial territory of diagonal branches and to develop a prediction model for clinically relevant branches using myocardial perfusion imaging…
- Trial name
- NCT03935542
- Where
- South Korea
- Volunteers
- 355 people
- Sponsor
- Bon-Kwon Koo
Rib Fractures
Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief System
The purpose of this study is to find out if patients having the ON-Q post-op Pain Relief System for pain management of multiple rib fractures will require fewer ventilator days, and will need less IV pain medicine to control…
- Trial name
- ON-Q (NCT00880529)
- Testing
- ON-Q bupivicaine administration, IV opioid administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cooper Health System
Coronary Microvascular Dysfunction, Coronary Microvascular Disease
A Placebo-Controlled Trial of CLBS16 in Subjects With Coronary Microvascular Dysfunction
This clinical trial will explore the efficacy and safety of GCSF-mobilized autologous CD34+ cells for the treatment of CMD in adults currently experiencing angina and with no obstructive coronary artery disease.
- Conditions
- Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Microvascular Coronary Artery Disease
- Trial name
- FREEDOM (NCT04614467)
- Testing
- CLBS16
- Where
- 7 sites in United States
- Volunteers
- 34 people
- Sponsor
- Lisata Therapeutics, Inc.
Stable Angina, Coronary Artery Disease
Stable Angina Management and Treatment
The Prospective REgistry of Stable Angina manaGEment and Treatment (PRESAGE) is an observational study on an all-comer stable angina population hospitalised in a highly specialized cardiovascular centre with cardiac surgery…
- Trial name
- PRESAGE (NCT03781492)
- Where
- Poland
- Volunteers
- 25,000 people
- Sponsor
- Silesian Centre for Heart Diseases
Acute Coronary Syndrome, High-Risk Chest Pain
BREVOC Study: Exhaled VOCs for High-Risk Chest Pain in the ED
Study Objectives 1. Screening and identification of diagnostic biomarkers: To establish the exhaled volatile organic compound (VOC) profile of patients with acute high-risk chest pain and to differentiate high-risk chest pain…
- Conditions
- Acute Coronary Syndrome, High-Risk Chest Pain, Volatile Organic Compounds
- Trial name
- BREVOC (NCT07379567)
- Testing
- observational study
- Volunteers
- 6,000 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Coronary Syndrome
Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180)
A-Phase: Evaluating patients with chest pain who are receiving approved drugs, to estimate the effectiveness of one type of blood thinner as compared to another type of blood thinner.
- Trial name
- NCT00251576
- Testing
- A-Phase: tirofiban; Z-Phase simvastatin, Duration of Treatment: A-Phase: minimum suggested 48 hours, maximum suggested 108 hours. Z-Phase: 2 years, Comparator: A-Phase: low molecular weight heparin, unfractionated heparin
- Volunteers
- 4,497 people
- Sponsor
- Organon and Co
Acute Coronary Syndrome
Medical Telephone Triage of Emergency Calls for Thoracic Pain
Thoracic pain is the main symptom of acute coronary syndrome (ACS), urgent and serious illness. Whereas hospital mortality decreased until reaching 10%, out-of-hospital mortality remains high: half of the deaths occur during the…
- Trial name
- DOREMI2 (NCT02042209)
- Where
- 3 sites in France
- Volunteers
- 4,205 people
- Sponsor
- University Hospital, Toulouse
Unstable Angina Pectoris
Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study
The purpose of this study is to evaluate the differences in pharmacokinetics and pharmacodynamics of ticagrelor and its active metabolite depending on the strategy of the drug administration in patients with unstable angina…
- Trial name
- NCT02612116
- Testing
- Pulverized ticagrelor sublingually, Pulverized ticagrelor orally, Integral ticagrelor
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Chest Pain, Epicardial Plaques
Addition of FFRct in the Diagnostic Pathway of Patients With Stable Chest Pain
Rationale: Patients with stable chest pain enter a diagnostic pathway where Coronary Computed Tomography Angiography (CCTA) is often the first line non-invasive test to detect coronary stenosis.
- Trial name
- Fusion (NCT05174247)
- Testing
- FFRct analysis
- Where
- Netherlands
- Volunteers
- 528 people
- Sponsor
- Erasmus Medical Center
Video Assisted Thoracic Surgery (VATS)
Comparison Effects of Three Regional Anesthetic Technique on Pain During Video-assisted Thorascopic Surgery(VATS)
In this study, our iş to compare effect of erector spinae plan block(ESP), paravertebral block(PVB) and mid-point transverse process to pleura block(MTP) on perioperative pain measured with analgesia nociceptive index monitor on…
- Trial name
- NCT06689449
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Stable Angina Pectoris
Comparison of Carvedilol and Atenolol on Anti-anginal and Metabolic Effects in Patients With Stable Angina Pectoris
There are few data regarding anti-anginal effects between beta-blockers with and without vasodilating property. Beta-blocker without vasodilating property is generally known to have unfavorable effects on glucose and lipid…
- Trial name
- NCT02547597
- Testing
- Carvedilol, Atenolol
- Where
- South Korea
- Volunteers
- 99 people
- Sponsor
- Gachon University Gil Medical Center
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
Coronary Heart Disease, Stable Angina Pectoris
BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)
The objective of this study is a comparative evaluation of BuMA stent and of EXCEL stent in terms of the extent of neointima formation at 3 months after implantation using OCT.
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Unstable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- NCT01752582
- Testing
- BuMA stent, EXCEL stent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sino Medical Sciences Technology Inc.
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