Clinical trials: Chest Trauma With Ribs Fractures
Trauma, Trauma Injury
Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures
Management of traumatic rib fractures continues to be a challenge for trauma surgeons. Currently, many analgesic options are available to patients suffering from rib fractures.
- Conditions
- Trauma, Trauma Injury, Pain, Acute
- Trial name
- NCT03574376
- Testing
- Bupivacaine Liposome Injection, Bupivacaine
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Chadrick Evans
Rib Fractures, Pain
Analgesic Effect of Intranasal Calcitonin on Patients With Fractured Ribs
This study, which will be conducted at the emergency room of the Sacré-Cœur hospital, requires the recruitment of 60 subjects and involves some telephone follow-up.
- Trial name
- NCT00444808
- Testing
- Intranasal calcitonin
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Université de Montréal
Rib Fractures
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.
- Trial name
- NCT04928300
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Rib Fracture
The Analgesic Effect of Retro-laminar Block Versus Paravertebral Block in Patients With Multiple Fracture Ribs
Rib fractures are a common injury, occurring in up to 10% of all trauma patients. Multiple rib fractures can be particularly painful and debilitating, making it difficult for patients to breathe and cough.
- Trial name
- NCT06757803
- Testing
- rertrolaminar block, paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Fracture Rib
Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture Ribs
Rib fractures are seen in more than 50% of patient spresenting with blunt chest trauma and are associated with significant morbidity, long-term disability and mortality .
- Trial name
- NCT05898958
- Testing
- thoracic paravertebral block, rhomboid intercostal and subserratus block
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Rib Fracture Multiple, Pain, Chest
RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe)
Traumatic rib fractures (RF) are a relatively common occurrence in patients of all ages, with a 10% incidence in all trauma patients and are associated with significant morbidity and mortality.
- Conditions
- Rib Fracture Multiple, Pain, Chest, Pain, Acute, Respiratory Failure
- Trial name
- RIB PAIN (NCT03770208)
- Testing
- Intervention: Lidocaine
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Western University, Canada
Hemothorax; Traumatic, Rib Fractures
IS Reduces Rib Fracture Complications
The incentive spirometer (IS) is a mechanical device that helps lung expansion. It is commonly used to prevent postoperative lung atelectasis and decreased pulmonary complications in patients who received cardiac, lung, or…
- Conditions
- Hemothorax; Traumatic, Rib Fractures, Rib Trauma
- Trial name
- NCT04006587
- Testing
- incentive spirometer
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Thorax; Fracture, Rib Fracture
Naproxen and Lidocaine Gel Combination for Rib Fracture
This study evaluates whether adding a topical gel containing naproxen and lidocaine to routine intravenous analgesic treatment improves pain relief in adults with isolated traumatic rib fractures presenting to the emergency…
- Conditions
- Thorax; Fracture, Rib Fracture, Pain Management
- Trial name
- NCT07706036
- Testing
- A gel combination containing 10% naproxen and 5% lidocaine, Dexketoprofen trometamol 50 mg IV
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara City Hospital Bilkent
Rib Fractures
Quality of Life in Patients With Traumatic Rib Fracture After Rib Fracture Surgery
This study is a prospective study. Patients with traumatic rib fractures are divided into control group and surgical (OP) group, depending on whether they undergo rib fracture fixation surgeries.
- Trial name
- NCT03487458
- Testing
- Rib Fixation Surgery
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Rib Fractures, Rib Fracture Multiple
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death.
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib; Fracture, With Flail Chest, Pain
- Trial name
- UNPIN (NCT05865327)
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Rib Fractures
Comparison of Lung Function Based on Electrical Impedance Tomography and CT Lung Volume in Patients With Rib Fractures
Our research uses the electrical impedance tomography system (EIT), which can use the applied current and measurement voltage through the body surface electrode group, and use the reconstruction algorithm to construct an image…
- Trial name
- EIT (NCT04946331)
- Testing
- Electrical impedance tomography system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Rib Fractures, Nonunion of Fracture
Impact of Time Interval Between Trauma and Operation on Clinical Outcome in Patients With Delayed Rib Fixation (Nonunion)
The goal of this monocentric observational study is to evaluate the outcomes of patients who underwent a delayed surgical stabilization of rib fractures/surgical stabilization of rib fracture nonunion (SSRFN) based on the timing…
- Trial name
- NCT06788067
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Basel, Switzerland
Rib Fractures
Cryo Rib Fracture Study
The purpose of this study is to determine if patients with rib fractures who undergo cryoablation of the intercostal nerves have improved pain control 7 days from procedure when compared to those who have a ESP catheter.
- Trial name
- NCT06347874
- Testing
- Cryoablation, ESP Catheter
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Rib Fractures
Erector Spinae Plane Blocks for the Early Analgesia of Rib Fractures in Trauma: a Feasibility Randomised Controlled Trial With Embedded Qualitative Assessment
To assess the feasibility and inform the design and conduct of a pragmatically conducted, interventional, multi-centre RCT in adult patients admitted to UK major trauma centres with rib fractures examining ESP block as an…
- Trial name
- ESPEAR (NCT07494851)
- Testing
- ESP Block
- Where
- 3 sites in United Kingdom
- Volunteers
- 27 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Rib Fractures, Pain
The Pain Control in Rib Fracture With Non-invasive Stabilization (RCT)
Brief summary: Background: Rib fractures are one of the most common causes of trauma disabilities and have become an important health issue. Patients usually suffer from severe pain.
- Conditions
- Rib Fractures, Pain, Thorax; Fracture
- Trial name
- NCT05080686
- Testing
- Posthorax Thoraxbelt
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Rib Fractures
Randomized Clinical Trial of Rib Fixation Versus Medical Analgesia in Uncomplicated Rib Fractures on Pain Control.
Uncomplicated costal fractures often result in persistent pain over the long term. Indeed, cohort studies showed that at 6 months, 22% of patients still had pain and 56% had functional disability.
- Trial name
- PAROS (NCT04745520)
- Testing
- Rib fixation, Analgesia
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Benoît Bédat
Fracture; Rib, Multiple
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs
To assess the analgesic and respiratory effect of continuous Erector Spinae Plane block versus Thoracic Epidural in patients with multiple fracture ribs.
- Trial name
- NCT03853330
- Testing
- Ultrasound, Bupivacaine HCl Inj 0.25%, Bupivacaine Hydrochloride, 0.125%-0.9% Injectable Solution
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Assiut University
Rib Fractures
Ultrasound-Guided Mid-Point Transverse Process to Pleura Block Versus Thoracic Paravertebral Block for Pain Management in Patients With Multiple Rib Fractures (A Prospective Randomized Double- Blinded, Non-inferiority Trial )
The aim of our study is to investigate whether the analgesic effect of MTPB is non inferior to that of TPVB in trauma patients with multiple rib fractures.
- Trial name
- NCT06981728
- Testing
- Mid point transverse to pleura block
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rib Fractures
Lidocaine Patches in Elderly Patients With Traumatic Rib Fractures
Many patients are prescribed lidocaine patches for rib fractures despite mixed evidence to their efficacy. The outcome of this trial offers significant benefit to patient care if it finds benefit of their use or if it does not.
- Trial name
- NCT05714631
- Testing
- 4% Lidocaine Patch
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Rib Fractures
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Rib fractures cause a significant amount of pain and are associated with an increased risk of lung infections, long hospitalization, and increased cost.
- Trial name
- NCT07145346
- Testing
- Suzetrigine (SUZ)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine