Clinical trials: Chest Wall Disorder
Angina Pectoris, Left Ventricular Wall Motion Abnormalities
Intraprocedural Determination of Myocardial Vitality Using 2 Different Imaging Methods
The investigators will compare myocard vitality diagnostics using 2D-Strain echography and MRI.
- Trial name
- NCT01934699
- Testing
- Cardiac ultrasound, MRI scanner
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- RWTH Aachen University
Stroke
Acute Effects After Stretching Respiratory Muscles on Ventilatory Pattern and Volume Distribution of Chest Wall
The purpose of study is to evaluate the acute effects of respiratory muscles stretching on ventilator pattern and volume distribution of chest wall in patients with right hemiparesis post-stroke and our hypothesis is that the use…
- Trial name
- NCT02416349
- Testing
- Respiratory Muscles Stretching, Control Group
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal de Pernambuco
Breast Cancer, Metastatic Breast Cancer
Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases
This study is to find an optimal dose of Imiquimod (IMQ) in the first part (Phase I) and test the effectiveness of the combination treatment of IMQ, cyclophosphamide (CTX), and radiotherapy (RT) in patients with skin metastases…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT01421017
- Testing
- Radiation, Imiquimod, Cyclophosphamide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Thoracic Aortic Aneurysms
Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms
An aortic aneurysm (thoracic or abdominal) is a permanent dilatation of the aorta caused by weakening in the arterial wall. The feared complication is aortic rupture or dissection, leading to potentially lethal aortic bleeding…
- Trial name
- NCT03142074
- Testing
- Biomechanical and microstructural analysis of ATAA, ECG-gated CT
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pectus Excavatum
Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum
This study is a Phase 3, multicenter, non-randomized study to evaluate the safety and efficacy of the next-generation outpatient Magnetic Mini-Mover Procedure (3MP) in 15 patients aged 8-14 years for the correction of pectus…
- Trial name
- 3MP (NCT01327274)
- Testing
- Magnetic Mini-Mover Procedure (Magnimplant)
- Where
- 3 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Harrison
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Breast Cancer, Dermatologic Complications
Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ
RATIONALE: Steroid therapy, such as mometasone furoate, may prevent radiation dermatitis caused by radiation therapy. It is not yet known whether mometasone furoate is more effective than a placebo in preventing radiation…
- Conditions
- Breast Cancer, Dermatologic Complications, Radiation Toxicity, Skin Reactions Secondary to Radiation Therapy
- Trial name
- NCT00438659
- Testing
- mometasone furoate
- Where
- 189 sites in United States
- Volunteers
- 176 people
- Sponsor
- North Central Cancer Treatment Group
Heart Failure
Cardiac Function and Inspiratory Muscles Performance
The purpose of this study is to determine whether ejection fraction and peak oxygen uptake have correlation on inspiratory muscle strength, chest wall volumes and quality of life in individuals with heart failure.
- Trial name
- NCT02763982
- Testing
- Physical evaluation
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Breast Cancer, Oncoplastic Breast Surgery
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin…
- Conditions
- Breast Cancer, Oncoplastic Breast Surgery, Oncoplastic Breast-conserving Surgery, Chest Wall Perforator Flap
- Trial name
- ScarABEO (NCT06906237)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Lung Cancer, Metastatic Cancer
Combined Deep Inspiration Breath Hold (DIBH)-Expiration Planning Technique in Patients With Lung Tumors in Close Proximity to the Chest Wall
The purpose of this study is to evaluate a new radiation planning and treatment delivery technique called Deep Inspiration Breath Hold (DIBH) and expiration technique.
- Trial name
- NCT04507828
- Testing
- Treatment Planning using the DIBH Technique
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Cystic Fibrosis, Bronchiectasis
Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements
The impact of high-frequency chest wall oscillation therapy on spirometry values (Forced Expiratory Volume, Forced Vital Capacity, Peak Expiratory Flow, Forced Expiratory Flow and Tidal Volume is investigated during use of…
- Trial name
- NCT03534986
- Testing
- International Biophysics AffloVest, Hill-Rom The Vest, Respirtech inCourage
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- International Biophysics Corporation
Critically Ill, Acute Lung Injury
Respiratory Mechanics and Pleural Effusion
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.
- Conditions
- Critically Ill, Acute Lung Injury, ARDS
- Trial name
- NCT00258518
- Testing
- mechanical ventilation/CT Scan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Policlinico Hospital
Breast Cancer, Breast Neoplasms
Imiquimod for Breast Cancer Patients With Chest Wall Recurrence or Skin Metastases
The purpose of this trial is to determine the safety and efficacy of Imiquimod, a Toll-like receptor 7 agonist in breast cancer (for chestwall recurrences or metastases to the skin).
- Trial name
- NCT00899574
- Testing
- Imiquimod
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Chest Wall Deformity, Funnel Chest
Chest Wall Deformities in Children - Epidemiological Data
Pectus excavatum (PE) or funnel breast is the most common congenital deformity of the chest wall, which occurs in about 1 in 400 births with a boy to girl ratio of 4: 1 to 3: 1.
- Trial name
- NCT04448574
- Testing
- Chest Wall Deformities Questionaire
- Where
- 2 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cystic Fibrosis
Comparison of Airway Clearance Therapy in Cystic Fibrosis Using the Same VEST Therapy Device But With Different Settings
Our primary hypothesis is that airway clearance therapy with sine waveform HFCWO using higher inflation pressures combined with both low and high oscillator frequencies will result in greater sputum production compared to sine…
- Trial name
- NCT00685035
- Testing
- HFCWC with higher pressure/variable-frequency settings, HFCWC with lower pressure/mid-frequency settings
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Minnesota
Thoracic Diseases
Effect of Manual Chest Wall Vibration on Respiratory Function and Chest Tube Duration After Thoracic Surgery
This study was conducted to determine the effects of a manual vibration technique applied to the chest wall on the duration of chest tube placement, secretion clearance, and hemodynamic parameters in patients with chest tubes.
- Trial name
- NCT07549555
- Testing
- Chest Wall Oscillation, Conventional Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Breast Cancer, Breast Neoplasm
Proton Radiation for Stage II/III Breast Cancer
The purpose of this study is to look at the rates of acute and long term adverse events of postoperative proton radiotherapy for complex loco-regional irradiation in women with loco-regionally advanced breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasm, Breast Tumor, Cancer of the Breast
- Trial name
- NCT01758445
- Testing
- Proton Radiotherapy
- Where
- 5 sites in United States
- Volunteers
- 220 people
- Sponsor
- Proton Collaborative Group
Coronary Artery Disease, Stable Angina
Detection of Coronary Vulnerable Plaque With Contrast-enhanced Magnetic Resonance Imaging
MRI has the ability to visualize the arterial vessel wall. Wall thickening and atherosclerotic plaque components can be visualized in the carotid arteries and the aorta.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina
- Trial name
- T9M (NCT00984776)
- Testing
- Contrast enhanced MRI with Gadofosveset
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Maastricht University Medical Center
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)
The objective of this study was to evaluate the use of high frequency chest wall oscillation (HFCWO) early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD).
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Undifferentiated Asthma/COPD
- Trial name
- NCT00181285
- Testing
- High Frequency Chest Wall Oscillator
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Chicago
Ascending Aortic Aneurysm
Biomechanical Properties of the Human Ascending Aortic Wall in Aneurysm
The aim of the study is to analyze the efficacy of the surgical tretment in patients with ascending aortic aneurysm and dilatation.
- Trial name
- NCT05839990
- Testing
- Surgery
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences