Clinical trials: Chiari Malformation Type I
Type I Chiari Malformation, Cerebral Hemodynamic
Analysis of Disturbances in Neurofluid Dynamics in Type I Chiari Malformations
A global analysis of craniospinal hemodynamics and hydrodynamics is necessary to better understand the pathophysiology of Chiari malformations.
- Conditions
- Type I Chiari Malformation, Cerebral Hemodynamic, Craniospinal Hydrodynamic, Phase Contrast MRI
- Trial name
- NEUROFLUX-C (NCT06502431)
- Testing
- phase contrast sequences
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Arnold-Chiari Malformation, Type 1
Arnold Chiari Malformation: the Otological Assessment as an Objective Criteria for Surgical Treatment
The aim of this study is to compare the value of multifrequency tympanometry between patients with surgical indication of treatment for a Chiari type I malformation and healthy volunteers.
- Trial name
- MCoto (NCT03295864)
- Testing
- Multifrequency tympanometry at Inclusion, Multifrequency tympanometry 6 month after surgery
- Where
- France
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chiari Malformation, Type 1
Identification of Genetic Mutations Involved in Chiari Type I Malformations
Although most cases of Chiari malformation type I (CM1) are sporadic, familial cases of CM1, with or without syringomyelia, suggest a genetic cause in the pathogenesis of these malformations.
- Trial name
- ChiariGene (NCT05165030)
- Testing
- Blood Sample
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris