Clinical trials: Child Development
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Autism Spectrum Disorders, Autism
Identification of Characteristics Associated With Symptom Remission in Autism
Autism is defined as a lifelong pervasive developmental disability, as such, symptom recovery is considered rare. Reports by Lovaas and McEachin, Smith \& Lovaas and more recently by Cohen, Amerine-Dickens, \& Smith, Smith Groen…
- Trial name
- NCT00938054
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obesity
Development of a Group Prenatal Care Intervention to Address Maternal and Child Non-Communicable Disease (NCD) Risk in American Samoa
To test the efficacy of a group prenatal care intervention to reduce the risk of obesity related health conditions during and after pregnancy in obese mothers and their infants.
- Trial name
- NCT04025268
- Testing
- Group Prenatal Care (GPNC), Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorder, Executive Functioning
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings.
- Trial name
- NCT06651086
- Testing
- Unstuck and On Target, Unified Protocol for Children
- Where
- 2 sites in United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Brain and Central Nervous System Tumors
Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma
RATIONALE: Studying samples of tumor tissue and blood in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00891722
- Testing
- biologic sample preservation procedure, laboratory biomarker analysis, questionnaire administration
- Where
- United Kingdom
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Children's Cancer and Leukaemia Group
Child Development
A New Designed Balance Platform for Children
People always come across with different floors which gradually affect dynamic balance. Dynamic balance is important in activities of daily life of all people.
- Trial name
- NCT03777995
- Where
- Cyprus
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
School Readiness, School Environment
Every Newborn Reach Up Early Education Intervention for All Children Education (ENREACH) Education
The goal of the project is to assess the scale-up of the program, focusing on improving school readiness among preschool children, enhancing capacity building for parents and teachers, and utilizing a cluster randomized…
- Trial name
- ENREACH-ED (NCT06890156)
- Testing
- ENREACH child-parent-teacher triad
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Neurodevelopmental Disorders, Lactation
Iron Supplement Effect on Child Development
Objective: To evaluate the effect of Iron supplement with two different amounts (one in the higher limit and another in the lower limit of the suggested amount) according to the presence of mutations in the HFE gene in the…
- Trial name
- NCT02690675
- Testing
- Iron fortified formula milk
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Weight-Estimation
Can Habitus Adapted Length Based Body Weight Estimation be Improved by Adding Further Parameters?
The purpose of this prospective single center study is to investigate if the accuracy of length based body weight estimation by the already investigated algorithm (CLAWAR) can be improved by adding another parameter.
- Trial name
- Including MUC (NCT02930928)
- Testing
- Accuracy of weight estimation
- Where
- Switzerland
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Autism Spectrum Disorder
Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation
The goal of this observational study is to identify behavioral and physiological markers of social alterations in Autism Spectrum Disorders compared to Typically Developping peers.
- Trial name
- SIRCUS (NCT05596331)
- Testing
- eye-tracker
- Where
- France
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Child Development
Added Sugar Intake and Brain Structure and Function
The purpose of this study is to learn if there is a relationship between added sugar intake during pregnancy, infancy, and toddlerhood and the brain's structure and function at 5-6 years old.
- Trial name
- GAINS BRAINS (NCT06640829)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorder
Validation of the Girls Questionnaire for Autism Spectrum Condition in French Langage
Autism spectrum disorders (ASD) are currently diagnosed at a rate of approximately 3 males per 1 female, while evidence suggests the rate may be 1.8 males per 1.2 females.
- Trial name
- fGQ-ASC (NCT06280521)
- Testing
- fGQ-ASC
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Childcare Quality, Child Development
THRIVE BY 3 Daycare to Promote Development/ Mental Health in 1&2 Year-olds
This study evaluates a preventive, knowledge enhancement and tailored quality building intervention to promote development and mental health in 1 and 2 year-olds.
- Trial name
- Tb3 (NCT03879733)
- Testing
- Thrive by Three, Treatment as usual (TAU)
- Where
- 3 sites in Norway
- Volunteers
- 1,531 people, healthy volunteers welcome
- Sponsor
- Regionsenter for barn og unges psykiske helse
Empathy
Small Moments Big Impact (SMBI)
Empathy is defined as sensitivity to the needs of others.Maternal empathy, or a mother's sensitivity to the needs of her child, is critical for healthy child development ,Small Moments, Big Impact: Supporting Maternal Empathy by…
- Trial name
- SMBI (NCT03887832)
- Testing
- SMBI digital app, media package, standard newborn and infant care
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Early Childhood, Neurodevelopment, Early Childhood, Anthropometry
Environmental Pollutants in Pregnancy - IoMumNEXT
Globally 12.6 million people, including 1.7 million children under the age of 5, die each year from environmental-related illnesses.
- Trial name
- IoMumNEXT (NCT06226311)
- Testing
- Data collection, Diagnostic Test: Urinary
- Where
- Portugal
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
PCOS, Offspring, Adult
Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study
The Offspring Born to Mothers with Polycystic Ovary Syndrome in Guangzhou Cohort study (PCOS-BIG) was established to investigate the short- and long-term effects of intrauterine exposure to maternal PCOS on the health of…
- Conditions
- PCOS, Offspring, Adult, Hyperandrogenism, Epigenetics
- Trial name
- PCOS-BIG (NCT03742011)
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
The Effect of Playful Physiotherapy Intervention
The goal of this quasi-experimental study is to evaluate the changes in emotional, behavioral, and psychosocial functioning of children aged 7-12 following a playful physiotherapy intervention.
- Trial name
- NCT07466147
- Testing
- Playful physiotherapy programme
- Where
- Estonia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Autism Spectrum Disorder (ASD), Autism
Judo Training for People With Autism Spectrum Disorder, Physical Fitness and Psychological Indicators
Physical fitness and psychological indicators are key factors in healthy development. Individuals with autism spectrum disorder (ASD) tend to have lower levels of physical fitness and mental health than their neurotypical peers.
- Trial name
- JUDOASD/PA/PSY (NCT07419919)
- Testing
- Judo training for people with ASD - training in integration groups with non-ASD people
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Child, Only, Metabolic Diseases
Nutritional Study in Spanish Pediatric Population
This study investigates the aspects related to the intake of food and nutrients, physical activity and sedentary behavior of Spanish children from 1 to 9 years.
- Conditions
- Child, Only, Metabolic Diseases, Child Development, Diet Habit
- Trial name
- EsNuPI (NCT03941392)
- Where
- Spain
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Fundacion Iberoamericana de Nutricion