Clinical trials: Child Development Disorder
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Disorders and Maternal Stress, Autism
CFT Guided Self-help Intervention: Parents of Autistic Children
This research will aim to test how practical, achievable and effective a brief, guided, self-help compassion focused intervention is for parents of autistic children aged 6-17 years old.
- Conditions
- Autism Disorders and Maternal Stress, Autism, Autism Disorder, Autism Spectrum Disorder
- Trial name
- CFT-GSH-PAC (NCT07498049)
- Testing
- Guided, self-help compassion-focused intervention for parents of autistic children
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Perinatal DHA and Folate Status, Neurological Development
Fish Oil and Folate Supplementation During Pregnancy
Pregnant women are randomised to supplementation with fish oil, methyl tetrahydro folic acid, both or a placebo during the second half of pregnancy.
- Trial name
- NUHEAL (NCT01180933)
- Testing
- fish oil, folate, fish oil + folate
- Where
- 3 sites in Germany, Hungary and 1 more
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Speech Sound Disorder
Sharing Books With Children
The promotion of language and communicative development in the early years is extremely important. Children who enter school with good language skills have better educational and economic success.
- Trial name
- NCT03006744
- Testing
- Phonological awareness training, Reading enjoyment training
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manchester
Premature Loss of Primary Molars, Space Maintenance
Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning
This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years.
- Conditions
- Premature Loss of Primary Molars, Space Maintenance, Dental Arch Development, Pediatric Tooth Extraction
- Trial name
- NCT06965777
- Where
- Egypt
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Cairo University
Autism, Parents
A Study on the Effect of Education Training on Parents With Autism Based on Denver Model
The goal of this clinical trial is to test the effects of parent training based on Denver model on parents' disease cognition level, coping style, parenting guilt, depression, anxiety and stress, quality of life, etc .
- Trial name
- NCT06126939
- Testing
- Educational training based on the Denver model
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Child Obesity
Development and Evaluation of the T.E.A.C.H. Study: A Randomized Control Trial
Using a randomized control design, this study seeks to develop and evaluate a nutrition intervention to increase Montessori teachers' nutrition knowledge, nutrition self-efficacy, nutrition teaching self-efficacy and cultural…
- Trial name
- NCT06926907
- Testing
- The Teacher Education and Classroom Habits (T.E.A.C.H.) Program
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Florida International University
Molar Incisor Hypomineralization
Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children From 8 to 12 Years Old in Dakahlia
The aim of this study is to assess the prevalence of MIH among a group of Egyptian children aged from 8-12 years old in Dakahlia governorate schools.
- Trial name
- MIH (NCT03583671)
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rheumatic Heart Disease, Rheumatic Heart Disease in Children
Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor
This is a Phase I/IIa, randomized, double-blind, placebo-controlled, dose-escalation clinical trial to test the candidate vaccine StreptInCor.
- Conditions
- Rheumatic Heart Disease, Rheumatic Heart Disease in Children, Vaccine Adverse Reaction, Rheumatic Diseases
- Trial name
- StreptInCorVac (NCT07078357)
- Testing
- StrepIncor
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Growth Failure, Mental Health Disorder
Growth-Health and Development in Children Exposed to Drugs During Pregnancy
"Children exposed to alcohol or drugs during pregnancy: Growth, health and development" Background Children exposed to drugs during pregnancy are at risk of developmental disorders.
- Conditions
- Growth Failure, Mental Health Disorder, Foetal Exposure During Pregnancy
- Trial name
- NCT02842645
- Where
- 2 sites in Norway
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Autism Spectrum Disorder
Emotional Skills Training with Social Robot
Autism is a neurodevelopmental disorder that involves difficulties especially in the sphere of social interaction, social communication, and restricted and stereotyped behavior patterns.
- Trial name
- NCT06179953
- Testing
- NAO intervention, Traditional intervention
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Vestibular Disorder
Vestibular Function and Motor Development in Small Children
Infants and toddlers with and without vestibular impairment will be tested blinded by pediatric physiotherapist with different age adequate motor scales in order to find out pathological motor patterns specifically associated to…
- Trial name
- NCT07079488
- Testing
- Motor proficiency scales
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Autism Spectrum Disorder
Role of Folinic Acid in Improving the Adaptive Skills and Language Impairment in Children With Autism Spectrum Disorder
No such study has been conducted in Pakistan so the primary objective of this study was to determine the role of folinic acid in improving the speech and adaptive skills while secondary objective was improvement of stereotype…
- Trial name
- NCT05013164
- Testing
- Folinic Acid
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Premature Birth, Psychological Stress
Parental Stress and Attachment in Preterm Infants
Introduction: Advances in neonatology mean a significant reduction in mortality in premature infants as well as an increase in the risk of morbidity in the medium, short and long term.
- Conditions
- Premature Birth, Psychological Stress, Physiological Stress
- Trial name
- NCT06813560
- Testing
- hair cortisol, salivary cortisol, salivary Oxytocin
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Preterm Birth, Neurodevelopment
Preterm Birth Cohort Study in Guangzhou
The Preterm Birth Cohort Study in Guangzhou (PBCSG) aims to explore the impact of genetic and environmental factors including life styles on preterm birth, to examine the interaction effect between these factors, and to follow up…
- Conditions
- Preterm Birth, Neurodevelopment, Immune Development, Host and Microbiome
- Trial name
- PBCSG (NCT03668327)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autism
Investigation of Neuroserpin as an Autism Candidate Gene
Previously it has been shown that Familial Encephalopathy with neuroserpin inclusion bodies (FENIB) patients develop abnormalities that partially overlap with Autism Spectrum disorders (ASD), confounded with additional features…
- Trial name
- NCT00917683
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Nutritional Stunting, Growth Failure
Nutritional Stimulation of Growth in Children With Short Stature
Short stature is a frequent reason for referral to a pediatric endocrinology clinic. Short stature is especially prevalent among those with failure to thrive (whose weight is significantly below the average weight of his/her…
- Trial name
- NCT04226586
- Testing
- Essential Amino Acid (EAA) group
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Intellectual Disability
Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities
This study will determine the comparative effectiveness of Go Act, a tailored advocacy curriculum versus Peer parent-directed peer learning for increasing parent activation for parents of youth with intellectual and developmental…
- Trial name
- NCT05986305
- Testing
- Go Act, Peer
- Where
- 2 sites in United States
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy, Autistic Disorder
Screening for Metabolic Problems in Mothers of Children With Autism and Typically Developing Children
The purpose of this research study is to screen for metabolic abnormalities that are maternal risk factors for having a child with autism.
- Conditions
- Pregnancy, Autistic Disorder, Folic Acid Deficiency
- Trial name
- NCT02674022
- Testing
- Prenatal supplement
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Developmental Disabilities, Psychological Wellbeing
90SecondParent Wellbeing: Weekly Health Letters for Parents of Children With Developmental Disabilities
Parents of children with developmental disabilities (DD) consistently report significant psychological distress, a vulnerability amplified during the COVID-19 pandemic due to intensified caregiving demands and reduced access to…
- Conditions
- Developmental Disabilities, Psychological Wellbeing, Parental Wellbeing
- Trial name
- NCT07869251
- Testing
- 90SecondParent Wellbeing
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre