Clinical trials: Child Malnutrition
Severe Acute Malnutrition in Childhood
Development and Field Testing of Ready-to-use-therapeutic Foods Made of Local Ingredients in Bangladesh for SAM Children
Around 0.5 million under-five children are currently suffering from severe acute malnutrition (SAM) in Bangladesh and are at risk of death. Children with SAM and complications should be treated in a health care facility.
- Trial name
- NCT01889329
- Testing
- RUTF-1, RUTF-2, Plumpynut
- Where
- Bangladesh
- Volunteers
- 490 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Shock Hypovolemic, Shock, Septic
Management of Shock in Children With SAM or Severe Underweight and Diarrhea
Diarrhea is one of the leading causes of under-five childhood mortality and accounts for 8% of 5.4 million global under-5 deaths.
- Conditions
- Shock Hypovolemic, Shock, Septic, Blood Transfusion, Adrenaline
- Trial name
- NCT04750070
- Testing
- Blood and Dopamine, Blood and adrenaline
- Where
- Bangladesh
- Volunteers
- 135 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vitamin D Deficiency, Obesity
Vitamin D Deficiency and Low Bone Mineral Content in Children
The Vitamin D study is designed to investigate the effect of body fat mass on vitamin D levels in children. Earlier studies have shown that individuals with increased fat mass may have low vitamin D levels.
- Trial name
- VDS (NCT00756899)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Malnutrition, Child Development
Tools to Improve Parental Recognition of Developmental Deficits in Children
In this study, we aim to improve child nutrition by increasing parents' awareness of their children's physical growth. We use a cluster-randomized trial design to evaluate two interventions that provide parents with regular…
- Trial name
- NCT02242539
- Testing
- Height measurement poster, Community-based monitoring
- Where
- Zambia
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- Boston University
Rickets
Ultrasound Imaging and Quantitative Vibro-Acoustic Assessment of Rickets Under the Age of Ten
The goal of this study is to find out if the use of ultrasound pictures of bones can spot changes in the growth areas of children with rickets, a condition that affects how bones harden.
- Trial name
- NCT06385938
- Testing
- Ultrasound with quantitative vibro-acoustic assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vitamin D Deficiency, Iodine Deficiency
Vitamin D, Iodine, and Lead Levels in Haitian Infants and Children.
Vitamin D deficiency is common worldwide, including in infants and children, and rickets remains a public health concern in many developing countries.
- Conditions
- Vitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
- Trial name
- Haiti (NCT02301520)
- Where
- 2 sites in Haiti
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Malnutrition
Acceptability of Nutrient Supplements Among Women and Children in Bangladesh
The study aims to confirm the acceptability of lipid-based nutrient supplements (LNS) for use as nutritional supplements for pregnant and lactating women (PLW) or infants and young children (IYC) and micronutrient powder (MNP)…
- Trial name
- NCT01129089
- Testing
- Lipid-based nutrient supplement, Micronutrient powder
- Where
- Bangladesh
- Volunteers
- 144 people
- Sponsor
- University of California, Davis
Malnutrition
Translating Adoption of Improved Varieties Into Nutritional Impact
The purposes of this study are (1) to determine whether child nutrition-focused adoption encouragement messages focused on Quality Protein Maize (QPM) and the availability of small quantities of QPM seed can be effective at…
- Trial name
- QPM (NCT02710760)
- Testing
- Adoption Encouragement Treatment, Consumption Encouragement Treatment
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Malnutrition, Child, Enteropathy
Study of Environmental Enteropathy and Malnutrition in Pakistan
Environmental Enteropathy (EE) is an acquired sub-clinical inflammatory gut condition in which alterations in intestinal structure, function, and local and systemic immune activation lead to impaired vaccine responses, decreased…
- Conditions
- Malnutrition, Child, Enteropathy, Vaccine Response Impaired, Stunting
- Trial name
- SEEM (NCT03588013)
- Testing
- Nutritional education, Ready to Use Therapeutic Food, Upper gastrointestinal endoscopy with biopsy
- Where
- Pakistan
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition, Child
Improving the Quality of Care for Children With Acute Malnutrition in Uganda
This is a cluster RCT in 6 health centres in Uganda, testing supportive supervision to improve health outcomes and quality of care of children with malnutrition
- Trial name
- NCT03044548
- Testing
- Supportive supervision
- Where
- Uganda
- Volunteers
- 700 people
- Sponsor
- WHO Collaborating Centre for Maternal and Child Health, Trieste
Malnutrition
Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children
The purpose of this study is to measure the impact of a fortified food on the nutritional and micronutrient status of malnourished children, compared with milk.
- Trial name
- NCT01643187
- Testing
- Beverage fortified with 21 vitamins and minerals, Lactose-free milk
- Where
- Guatemala
- Volunteers
- 1,000 people
- Sponsor
- Association for the Study and Prevention of HIV/AIDS
Child Development, Parenting
The Sugira Muryango PLAY Collaborative
The Research Program on Children and Adversity (RPCA) has successfully grown its evidence-based home-visiting program-Sugira Muryango (SM)-in Rwanda, as policies and programs aligned with the Rwandan social protection system have…
- Conditions
- Child Development, Parenting, Parent-Child Relations, Child Malnutrition
- Trial name
- NCT04257383
- Testing
- Sugira Muryango
- Where
- Rwanda
- Volunteers
- 1,333 people, healthy volunteers welcome
- Sponsor
- Boston College
Undernutrition, Wasting
Improvement of Nutrition, Digestion, and Respiration in Children in Vietnam Using Oral Nutritional Supplementation
Evaluating the effect of using Oral Nutritional Supplementation toward nutrition status, digestive disorders, upper respiratory disorders, and picky eating in children aged 24 - 59 months.
- Conditions
- Undernutrition, Wasting, Malnourished
- Trial name
- NCT06708546
- Testing
- Dielac Grow Plus
- Where
- Vietnam
- Volunteers
- 981 people
- Sponsor
- Tu Nguyen Song
Pediatric Cancer, Nutrition Related Cancer
Pediatric Oncology Nutrition Intervention Trial
Nearly 60% of pediatric patients diagnosed with cancer develop malnutrition caused by a combination of disease burden, side effects of chemotherapy, and the intensity of cancer treatment.
- Conditions
- Pediatric Cancer, Nutrition Related Cancer, Nutrition Aspect of Cancer, Muscle Loss
- Trial name
- POINT (NCT06175273)
- Testing
- Oral Nutrition Supplement, Tube Feed, Cyproheptadine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corey Hawes
Low Birthweight, Stunting
Impact of Benazir Nashonuma Program (BNP) on Maternal and Child Nutritional Status
The purpose of this study is to evaluate the impact of Benazir Nashonuma Program (BNP) which includes specialized nutritious food (SNF) augmented with specific reproductive health interventions during pregnancy on proportion of…
- Conditions
- Low Birthweight, Stunting, Wasting, Malnutrition, Child
- Trial name
- NCT05836961
- Testing
- Benazir Nashonuma Program (BNP)
- Where
- Pakistan
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Acute Malnutrition With no Complications
Effectiveness of an Alternative Protocol in the Management of Acute Malnutrition
This experimental study aims to test an alternative protocol for managing acute malnutrition in children aged 6-59 months in Burkina Faso.
- Trial name
- Alternat-MAL (NCT06792370)
- Testing
- ready-to-use therapeutic food (for children with MAM), Ready-to-use supplementary food, Ready to Use Therapeutic Food - Reduced dose 1
- Where
- Burkina Faso
- Volunteers
- 3,521 people
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Malnutrition
Food and Agricultural Approaches to Reducing Malnutrition
The aim of this study is to evaluate the potential of reducing young child undernutrition in low-income countries through an integrated program that trains women's groups in agriculture, nutrition, child care and hygiene.
- Trial name
- FAARM (NCT02505711)
- Testing
- Homestead Food Production program
- Volunteers
- 2,705 people, healthy volunteers welcome
- Sponsor
- Sabine Gabrysch
Gestational Weight Gain, Diet, Food, and Nutrition
Nutri-CAP: Nutrition for Children, Adolescent Girls, and Pregnant Women in Slums of Dhaka City
The objective of the research project is to establish an evidence-based sustainable nutrition service delivery platform for optimizing pregnancy weight gain, increasing dietary diversity of adolescent girls, and ensuring proper…
- Conditions
- Gestational Weight Gain, Diet, Food, and Nutrition, Undernutrition, Health Behavior
- Trial name
- NCT05311436
- Testing
- Experimental - Intensive nutrition counselling for pregnant, adolescent and under2 children
- Where
- Bangladesh
- Volunteers
- 3,278 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malnutrition, Developmental Disabilities
Promoting Physical Growth and Positive Development in Severely Stunted Guatemalan Children
This study seeks to evaluate the impact of an intensive home-based education intervention targeting severely stunted Guatemalan children for catch up growth and improved development.
- Trial name
- NCT02509936
- Testing
- Home-based nutrition education, Standard-of-care nutrition support
- Where
- Guatemala
- Volunteers
- 324 people
- Sponsor
- Wuqu' Kawoq, Maya Health Alliance
Small Intestine Bacterial Overgrowth
Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi Children
The purpose of this Phase IIa study is to identify the most effective antibiotic regimen to treat small intestine bacterial overgrowth (SIBO) in impoverished Bangladeshi children.
- Trial name
- NCT07451171
- Testing
- Trimethoprim-sulfamethoxazole (TMP/SMX), Metronidazole, Amoxicillin-Clavulanate (4:1 formulation)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- University of Virginia