Clinical trials: Childbirth
Birth
Trial of Underwater Birth
Evaluate maternal perinatal outcomes in adult low-risk laboring people randomized to waterbirth compared to those randomized to birth on land.
- Trial name
- TUB (NCT07313319)
- Testing
- Waterbirth
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of New Mexico
Nicotine Dependence, Nicotine Dependence, Cigarettes
Comparing the Pharmacokinetics of Nicotine Salt Based ENDS in Healthy Smokers
A Ten Sequence, Open Label, Randomized Crossover Study Comparing Nicotine Pharmacokinetics of JUUL 1.7% and JUUL 5% Nicotine Salt Based ENDS Products, in Healthy Adult Smokers.
- Conditions
- Nicotine Dependence, Nicotine Dependence, Cigarettes, Tobacco Use, Tobacco Smoking
- Trial name
- NCT03593239
- Testing
- Tobacco flavored JUUL 1.7% ENDS, Tobacco flavored JUUL 5% ENDS, Mint flavored JUUL 1.7% ENDS
- Where
- New Zealand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Urinary Incontinence, Anal Incontinence
Tridimensional Pelvic Floor Ultrasound and Quality of Life Scores Questionnaires in Nulliparous or Parous Women
Evaluation of the impact of the delivery in the system of suspension and sustentation of pelvic floor, by 3D ultrasound and quality of life questionnaires.nt
- Conditions
- Urinary Incontinence, Anal Incontinence, Sexual Dysfunction, Self Esteem
- Trial name
- NCT03656601
- Testing
- 3D pelvic ultrasound
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cerclage, Cervical, Cervical Insufficiency
Effectiveness of Cervico-isthmic Cerclage
This study compares the rate of live births before and after cervico-isthmic cerclage in 3 hospitals in the last 10 years. The hypothesis is that cerclage significantly increases the rate of live births in women with cervical…
- Trial name
- CERCEI LB (NCT04722536)
- Testing
- Cervico-isthmic cerclage
- Where
- 3 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon
Injections, Intradermal
Performance and Safety Evaluation of an Intradermal Delivery Device
The purpose of this study is to evaluate whether an investigational vaccine delivery device (the ID adapter) can safely and precisely inject liquid into the intradermal layer of the skin.
- Trial name
- NCT01359111
- Testing
- PATH ID Adapter
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PATH
Hepatitis C, Chronic Hepatitis C
Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C
The Birth-Cohort Evaluation to Advance Screening and Testing for Hepatitis C (BEST-C) compares the effectiveness of the birth cohort HCV screening strategy with the current risk-based screening approach to detect previous…
- Trial name
- Best-C (NCT02123212)
- Testing
- Mailer, In-person recruitment, EHR Alert
- Where
- 3 sites in United States
- Volunteers
- 29,607 people, healthy volunteers welcome
- Sponsor
- National Opinion Research Center
Dysphagia of Newborn
The Effects of Pacifier-Activated Lullaby on Oral Feeding Among Preterm Infants
Preterm infants often have difficulty learning how to feed by mouth because the coordination of sucking, swallowing, and breathing develops later in pregnancy.
- Trial name
- Music therapy (NCT07819734)
- Testing
- Pacifier-Activated Lullaby (PAL) Therapy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
OME - Otitis Media With Effusion, AOM - Acute Otitis Media
In-Office Tympanostomy Tube Placement in Children (OTTER)
A prospective, single-arm, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula Iontophoresis and Tube Delivery Systems for children in an office setting.
- Trial name
- OTTER (NCT03323736)
- Testing
- Iontophoresis & tube placement, Tube placement
- Where
- 19 sites in United States, Canada
- Volunteers
- 370 people
- Sponsor
- Tusker Medical
Respiratory Distress Syndrome, Newborn
Surfactant Via Endotracheal Tube vs. Laryngeal Mask Airway (LMA) in Preterm Neonates With Respiratory Distress Syndrome
In this study, newborn babies with respiratory distress syndrome (RDS), receiving oxygen via nasal continuous airway pressure (CPAP) modalities, and needing surfactant treatment will be randomized to standard delivery of…
- Trial name
- NCT02164734
- Testing
- Endotracheal intubation, Laryngeal mask airway, remifentanil
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Albany Medical College
Babies Born Very Preterm
In-line Filtration to Reduce Systemic Inflammatory Response Syndrome in Babies Born Very prEtErm
While venous access is an essential part of caring for the preterm neonate potential severe adverse events, including contamination of fluids with bacteria, endotoxins and particulates could occur (Bethune 2001).
- Trial name
- FRISBEE (NCT02686060)
- Testing
- 0.2 micron positively charged PALL Corporation filters and 1.2 micro IV in-line filters used for lipid administration
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Infant
Evaluation of the Risks and Benefits of Abdominal Massage Treatment in Neonatalogy in Premature Children
Premature birth creates difficulties for the child in starting his diet and digestion. The immaturity of the major vital functions complicates the abdominal transit.
- Trial name
- PREMASS (NCT03681782)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Acute Pain, Cesarean Delivery
NSS-Bridge Device for Post-Cesarean Delivery Pain
The current opioid epidemic has led to a renewed interest in exploring non-pharmacological techniques to treat post-operative pain.
- Trial name
- NCT03830307
- Testing
- NSS-2-Bridge
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Very Low Birth Weight Infants
Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants
Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system and stimulate the immune system. Lactobacillus reuteri was shown to reduce candida colonization.
- Trial name
- NCT01531192
- Testing
- Lactobacillus reuteri, Nystatin
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Breast Cancer, Stress Disorders, Post-Traumatic
Expanding Rural Access: Distance Delivery of Support
The major goal of this project is to test the feasibility and acceptability of using videoconferencing to provide support groups led by trained facilitators to rural women with breast cancer in northern California.
- Conditions
- Breast Cancer, Stress Disorders, Post-Traumatic, Depression
- Trial name
- NCT00186511
- Testing
- workbook/journal on coping with breast cancer, supportive expressive group therapy using videoconferencing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Peripheral Arterial Disease
PQ Bypass Guide Wire Delivery System for Femoropopliteal Bypass
To assess the safety of performing a percutaneous fem-pop bypass using the PQ Bypass Guidewire Delivery System and commercially available stent grafts.
- Trial name
- PQB4FP1 (NCT01930071)
- Testing
- PQ Bypass Guide Wire Delivery System
- Where
- New Zealand
- Volunteers
- 4 people
- Sponsor
- Endologix
Serious Concerns
Prevalence and Risk Factors for Serious Birth Concerns in Unselected Population of Mothers
The aim of this study is to determine the prevalence of significant concerns about childbirth and their impact on the course and outcome of childbirth.
- Trial name
- RiskfSBC (NCT05216848)
- Testing
- Wijma Delivery Expectancy Questionnaire, Clinical data collection
- Where
- Slovakia
- Volunteers
- 700 people
- Sponsor
- Comenius University
Alcohol Abuse
Health Explorer - Optimizing Alcohol Brief Interventions
The aims of the study are to develop and refine tailored motivational brief interventions that are parallel in structure but have varied delivery modalities (computer vs.
- Trial name
- NCT01370226
- Testing
- CBI, TBI
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy
Study to Evaluate the Pharmacokinetics (PK), Safety, Tolerability of Single-Dose Transdermal Rotigotine in Japanese and Caucasian Healthy Male / Female Subjects
To investigate the Pharmacokinetics (PK) of transdermally delivered Rotigotine in Japanese and Caucasian Female and Male Healthy Subjects.
- Trial name
- NCT01761526
- Testing
- Rotigotine transdermal patch
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- UCB BIOSCIENCES GmbH
Obesity Complicating Childbirth, Fetal Anomaly
Pannus Assistance Needed for Obstetric Ultrasound Studies
The goal of this randomized controlled trial is to evaluate whether use of a pannus retractor adhesive improves fetal anatomic ultrasound examinations.
- Trial name
- NCT05764408
- Testing
- traxi® Panniculus Retractor
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate
Respiratory Distress Syndrome, Preterm Pregnancy
Less Invasive Surfactant Administration in Late Preterm or Early Term Born Infants
The aim of this study is to see if giving less invasive surfactant administration (LISA) during high-flow nasal cannula (HFNC) oxygen treatment reduces the need for invasive ventilation in babies with breathing problems born 2-6…
- Conditions
- Respiratory Distress Syndrome, Preterm Pregnancy, Surfactant Deficiency Syndrome Neonatal
- Trial name
- NCT06421506
- Testing
- Less invasive surfactant administration during high flow nasal cannula treatment
- Where
- United Kingdom
- Volunteers
- 245 people
- Sponsor
- King's College Hospital NHS Trust