Clinical trials: Childbirth-related Trauma
Stress Disorders, Post-Traumatic
Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment
Posttraumatic stress disorder (PTSD) is prevalent among Veterans and effective evidence-based psychotherapies (EBPs) for PTSD have been implemented within the Veterans Health Administration (VHA).
- Trial name
- NCT06335589
- Testing
- EBP-Massed, EBP-TAU
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Birth, First, Pregnancy Related
The Effect of the Continuous Midwifery Care Model on Birth Outcomes
It is the right of both the mother and her baby to receive the best care and give birth in the best way possible for every pregnant woman.
- Conditions
- Birth, First, Pregnancy Related, Newborn; Fit, Trauma, Psychological
- Trial name
- NCT06020339
- Testing
- The midwife-led continuous care model (MLCC)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Post-traumatic Stress Disorder, Stress Disorders
Effectiveness of Cognitive Processing Therapy in Pregnant Women With a History of Pregnancy Loss/Complication
The purpose of this study is to examine the effects of experiencing a previous pregnancy loss or complication on current physiological and emotional aspects of a current pregnancy.
- Conditions
- Post-traumatic Stress Disorder, Stress Disorders, Anxiety, Depression
- Trial name
- NCT01277354
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
PTSD
Innovative Service Delivery for Secondary Prevention of PTSD
The purpose of this study is to determine whether therapy for Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) veterans with Post-traumatic Stress Disorder (PTSD) symptoms can be delivered effectively using…
- Trial name
- NCT01177488
- Testing
- Behavioral Activation Therapeutic Exposure (BATE)
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Charleston Research Institute
Mental Health, Physical Health
Parental Well-being After Childbirth in Switzerland
Improving maternal and child health is a global priority, with increasing emphasis on ensuring women and their families not only survive but also thrive after childbirth.
- Conditions
- Mental Health, Physical Health, Postpartum, Parents
- Trial name
- SOCRATES (NCT06886841)
- Where
- 2 sites in Switzerland
- Volunteers
- 4,200 people
- Sponsor
- Laurent Gaucher
Medical Device-Related Pressure Injury, Prematurity
Non-Invasive Ventilation Interfaces and Nasal Pressure Injury in Preterm Infants
The goal of this randomized controlled clinical trial is to learn whether different non-invasive ventilation interfaces can prevent medical device-related nasal pressure injury in preterm infants receiving respiratory support in…
- Trial name
- NIV-MDRPI (NCT07521410)
- Testing
- Binasal Prong, Nasal Cannula, Nasal Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Pregnancy Related, Delivery; Injury, Maternal
Manual Physical Therapy During Pregnancy on Post Partum Perineal Trauma and Pain
The purpose of this study is to explore the impact of pelvic floor physical therapy during pregnancy on delivery and the impact on the woman's body and function.
- Conditions
- Pregnancy Related, Delivery; Injury, Maternal, Pelvic Floor Disorders
- Trial name
- NCT04660708
- Testing
- manual physical therapy
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Milwaukee
Acute Lung Injury, Pulmonary Injury
Electronic Nicotine Delivery Devices and Potential Progression to Acute Lung Injury
This is an observational - data and specimen collection study. There have been increasing reports of vaping-induced lung injury, including severe lung injury and rare cases of death.
- Conditions
- Acute Lung Injury, Pulmonary Injury, Electronic Cigarette Use, Electronic Cigarette Related Lung Injury
- Trial name
- ENDALI (NCT05316727)
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Labor Complication, Avulsion
The Association Between Kristeller Maneuver and Pelvic Floor Trauma After Vaginal Delivery
We want to investigate the association between fundal pressure in the second stage and the risk of levator ani muscle (LAM) injury.
- Trial name
- NCT03752879
- Testing
- Fundal Pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Post Traumatic Stress Disorder, Schizophrenia
PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
As in the general population, there is no clear standard of care within Veterans Affairs Medical Centers for treating posttraumatic stress disorder (PTSD) among individuals with severe mental illness (SMI).
- Conditions
- Post Traumatic Stress Disorder, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- PTSD/SMI (NCT01542229)
- Testing
- Prolonged Exposure for PTSD (PE) + Treatment as Usual (TAU), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Acute Stress Disorder
Swiss TrAumatic biRth Trial
This randomized controlled study aims to investigate the effects of a brief computerized intervention (the computer game "Tetris") on intrusive memories and other posttraumatic stress symptoms following an emergency cesarean…
- Trial name
- START (NCT03576586)
- Testing
- Brief computerized intervention
- Where
- Switzerland
- Volunteers
- 147 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
To Compare 2 Models of Midwifery Care in Maternity Care
Support and Personalized Care in Alternative Midwifery Birth Units Versus Traditional Units in France: Effects on the Psychological Health of Couples and on the Health of the Mother and Child at the Age of 2 Years.
Majority of pregnancies and childbirths in France occur without complication. While the impact of care failure on maternal and neonatal morbi-mortality is now well- established, the literature reveals that an overmedicalization…
- Trial name
- PhysioCareTwo (NCT06630741)
- Testing
- alternative midwifery units (AMU)
- Where
- 3 sites in France
- Volunteers
- 793 people
- Sponsor
- Rennes University Hospital
Anemia
Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO
The investigators seek to determine whether providing inhaled nitric oxide (iNO; a vasodilator) will improve the delivery of oxygen to the brain, kidney and intestines of preterm neonates during and after the subject receives a…
- Trial name
- iNO-TRAGI (NCT02851472)
- Testing
- Inhaled Nitric Oxide
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- New York Medical College
Preterm Birth, Bronchopulmonary Dysplasia
Improving Prematurity-Related Respiratory Outcomes at Vanderbilt
The goal of IMPROV is to identify molecular mechanisms that contribute to lung injury and long-term breathing problems in preterm infants by investigating two interrelated biochemical pathways: the urea cycle-nitric oxide pathway…
- Conditions
- Preterm Birth, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
- Trial name
- IMPROV (NCT01460576)
- Where
- 2 sites in United States
- Volunteers
- 253 people
- Sponsor
- Vanderbilt University Medical Center
PTSD - Post Traumatic Stress Disorder, PTSD (Childbirth-Related)
The New Empowerment After eXposure to Trauma (NEXT) Study
The NEXT Study is a randomized controlled pilot examining the feasibility and acceptability of a revised perinatal PTSD protocol.
- Trial name
- NEXT (NCT07175025)
- Testing
- Narrative Exposure Therapy (NET)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
PTSD
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce…
- Trial name
- TAPS (NCT05486793)
- Testing
- Written Exposure Therapy (WET), Emotion Focused Supportive Therapy (EFST)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston University
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Pregnancy, High Risk, Parturition Complication as Antepartum Condition
The Periviable Birth Plan
Pregnant women who are at risk of delivering their infants in the periviable period can suffer a large amount of stress and anxiety. Moreover, many women feel a loss of control over their own pregnancy.
- Conditions
- Pregnancy, High Risk, Parturition Complication as Antepartum Condition, Anxiety, PTSD
- Trial name
- NCT03061864
- Testing
- Periviable Birth Plan
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Albany Medical College
Bronchopulmonary Dysplasia, Preterm
Body Weight Growth After Birth and Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is one of the most common, complex, and severe diseases in preterm infants. BPD was first described as chronic pulmonary disease in survivors of severe respiratory distress syndrome (RDS) in 1967…
- Trial name
- NCT05053269
- Testing
- good body weight growth, poor body weight growth
- Where
- China
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University