Clinical trials: Childhood Asthma
Asthma Attack
Phenotyping and Classifying Asthma Exacerbations
An observational study in patients between 12 and 70 years old with an acute asthma exacerbation, to determine the relation between phenotypical characteristics and the treatment response.
- Trial name
- ExCluSieF (NCT05304039)
- Testing
- Questionnaires, Spirometry, Fractional Exhaled Nitric Oxide (FeNO)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Franciscus Gasthuis
Asthma in Children
Study for Children & Adolescent With Severe Asthma With an Eosinophilic Phenotype Treated With Mepolizumab
Open label, observational cohort study conducted to collect demographics, clinical characteristics and outcome observational data from children (6-17 years) with a clinical diagnosis of severe asthma in 2 countries (Spain and…
- Trial name
- CASAM (NCT05139381)
- Testing
- Mepolizumab
- Where
- United Kingdom
- Volunteers
- 148 people
- Sponsor
- King's College Hospital NHS Trust
Asthma
Piloting a Dietary Vitamin E Intervention During Pregnancy
In the last forty years the prevalence of asthma has increased in westernised countries. We have hypothesised that this increase may be a consequence of changing diet.
- Trial name
- NCT01661530
- Testing
- Vitamin E enhanced soup, Non-enhanced soups
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- University of Aberdeen
Asthma in Children
Asthma Navigator Intervention to Improve Health Equity in Children
The goal of this study is to improve health equity in children aged 5-16.9 years admitted to the PICU for asthma. The objectives are: To identify the factors related to differential experiences of asthma self-management To pilot…
- Trial name
- NCT06513832
- Testing
- The asthma navigator
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Asthma, Healthy
Inflammatory Markers in Exhaled Breath (Condensate) in Childhood Asthma
Background: Exhaled nitric oxide and inflammatory biomarkers in exhaled breath condensate may be useful to diagnose and monitor childhood asthma.
- Conditions
- Asthma, Healthy, Children
- Trial name
- NCT00404976
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Shortness of Breath, Asthma in Children
The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome
Our study aiming to look in improvement of Pediatric Respiratory Assessment Measure (PRAM) score as a primary outcome. The secondary outcomes involving the need for second step management, need for admission and possible side…
- Conditions
- Shortness of Breath, Asthma in Children, Epinephrine Causing Adverse Effects in Therapeutic Use, Salbutamol Adverse Reaction
- Trial name
- NCT05667727
- Testing
- nebulized epinephrine, Salbutamol
- Where
- Oman
- Volunteers
- 30 people
- Sponsor
- Oman Medical Speciality Board
Infant, Premature, Diseases, Infant
The Alberta BLOOM Long Term Follow Up Study
This is a prospective, observational clinical cohort study involving children born very preterm at less than 31 weeks and six days gestation.
- Conditions
- Infant, Premature, Diseases, Infant, Asthma, Asthma in Children
- Trial name
- BLOOM-LTFU (NCT04641000)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Calgary
Pediatric Asthma, Acute Asthma
Bilevel Positive Airway Pressure (BPAP) for Severe Asthma
The goal of this clinical trial is to assess the feasibility of early initiation of bilevel positive airway pressure (BPAP) in the emergency department (ED) for children with severe asthma exacerbations.
- Conditions
- Pediatric Asthma, Acute Asthma, BiPAP, Non-invasive Positive Pressure Ventilation
- Trial name
- NCT07582211
- Testing
- Bilevel positive airway pressure ventilation
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Columbia University
Asthma
The Genetics of Severe Asthma in Children
Near fatal asthma exacerbations are one of the most common causes of critical illness in children, accounting for approximately ten thousand intensive care unit (ICU) admissions per year in the United States.
- Trial name
- NCT01238432
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center
Childhood Asthma
Asthma Link: A Real World Application of School Supervised Asthma Therapy
The goal of this study is to assess the feasibility of a clinical trial to evaluate the impact and process of deploying school-supervised asthma therapy in a real-world setting for children with poorly controlled asthma (aged…
- Trial name
- NCT04942379
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Massachusetts, Worcester
Bronchopulmonary Dysplasia, Preterm Infant Development
PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm Infants
The goal of this clinical trial is to understand the impact of respiratory microbiome maturation in respiratory health of preterm infants under 32 gestational weeks.
- Conditions
- Bronchopulmonary Dysplasia, Preterm Infant Development, Asthma Childhood, Bronchiolitis
- Trial name
- PremaBiom (NCT07411261)
- Testing
- Nasal swab, blood sampling, Mother milk sampling
- Where
- 6 sites in France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Hyperlipidemias, Diabetes
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful…
- Conditions
- Hyperlipidemias, Diabetes, Depression, Pediatric Asthma
- Trial name
- NCT06903897
- Testing
- WE CARE SDOH System, Standard Pediatric Care
- Where
- 3 sites in United States
- Volunteers
- 68,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Asthma
Achieving Control of Asthma in Children In Africa
The main aim of the study is to identify altogether 3000 children aged between 12 and 16 years old with asthma symptoms in six sub-Saharan African countries.
- Trial name
- ACACIA (NCT03990402)
- Where
- 6 sites in Ghana, Malawi and 4 more
- Volunteers
- 3,767 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma Childhood
Application Construction and Effect Evaluation of Family-empowered Pulmonary Rehabilitation in School-age Children With Asthma
Study Purpose: To develop a pulmonary rehabilitation intervention program suitable for school-age children with asthma, and to evaluate its effectiveness in improving asthma control in children through a prospective randomized…
- Trial name
- NCT07558954
- Testing
- Family-empowered pulmonary rehabilitation, Conventional pulmonary rehabilitation care
- Volunteers
- 92 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Asthma, Allergy
Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy
To establish efficacy and safety of HDM sublingual Immunotherapy (HDM-SLIT) by comparing Odactra and placebo, when given sublingually for 3 years to high risk infants aged between 6 to 12 months at enrollment in preventing the…
- Trial name
- PAPA (NCT05113394)
- Testing
- HDM sublingual Immunotherapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Breathing Techniques, Asthma Control Level
Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with…
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients
- Trial name
- NCT07025616
- Testing
- Buteyko, Asthma reliever and controller
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Ivan Sofian Wibowo
Asthma in Children
Association Between Household Health Behaviors and Asthma in Children
This study plan to study the association between household health behavior (cleaning habits) and children's asthma. In addition, reconfirm the health effects of indoor environmental exposure to phthalates plasticizers, mite…
- Trial name
- ABHHBaAiC (NCT04565964)
- Testing
- change the health behaviors to clean indoor environment
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma
Montelukast in Modulating Exacerbations of Asthma in Children
The purpose of the study is to determine if Montelukast added to other therapy, if any, will reduce the severity of asthma symptoms in children during the high incidence of respiratory viral infections that occur in children in…
- Trial name
- NCT00196547
- Testing
- Montelukast (drug)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Firestone Institute for Respiratory Health
Status Asthmaticus
Early Noninvasive Positive Pressure Ventilation in Children With Status Asthmaticus
Status asthmaticus is recognized as a common cause of morbidity in children in the United States. In recent years, hospitalization rates have reached an all time high.
- Trial name
- NCT01188473
- Testing
- NPPV plus standard of care
- Where
- United States
- Sponsor
- Southern Illinois University
Childhood Asthma
Flunisolide HFA in Children With Small Airway Disease
The purpose of this study is to see how two doses of Flunisolide HFA (an FDA approved inhaled medication to treat asthma) affect the small airways in children with asthma.
- Trial name
- NCT02404103
- Testing
- Flunisolide HFA
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Louisville