Clinical trials: Childhood Asthma
Asthma Acute, Asthma Childhood
ASMact: Study on Management of Bronchial Asthma
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
- Conditions
- Asthma Acute, Asthma Childhood, Asthma in Children, Asthma Crisis
- Trial name
- NCT07412769
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Obesity-associated Asthma
Metformin Treatment for Children With Obesity-associated Asthma
The goal of this clinical trial is to learn if metformin can improve asthma control in overweight and obese children with mild, moderate, or severe asthma.
- Trial name
- MOACT (NCT07622290)
- Testing
- Metfomin
- Where
- Qatar
- Volunteers
- 182 people
- Sponsor
- Prof Ibrahim Janahi
Molar Incisor Hypomineralization, Asthma in Children
Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives
The aim of this study is to assess the prevalence of molar incisor hypo mineralization among children who have been treated with asthmatic drugs during the first three years of life.
- Trial name
- NCT04103710
- Where
- Egypt
- Volunteers
- 167 people
- Sponsor
- Cairo University
Hyperlipidemias, Diabetes
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful…
- Conditions
- Hyperlipidemias, Diabetes, Depression, Pediatric Asthma
- Trial name
- NCT06903897
- Testing
- WE CARE SDOH System, Standard Pediatric Care
- Where
- 3 sites in United States
- Volunteers
- 68,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Asthma
4-Week Study of Efficacy, Safety and PK of Albuterol-HFA Versus Proventil-HFA in Pediatric Asthma
This 4-week clinical study evaluates the efficacy and safety of Albuterol Sulfate HFA Inhalation Aerosol in comparison with the Active Control, Proventil-HFA (3M Pharmaceuticals, Inc) in pediatric patients (4-11 years old) with…
- Trial name
- NCT00634517
- Testing
- Armstrong Albuterol Sulfate Inhalation Aerosol, Albuterol Sulfate Inhalation Aerosol
- Where
- 8 sites in United States
- Volunteers
- 48 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma
Pilot Study of Magnesium Infusions in Pediatric Asthma
This is a prospective randomized pilot study that seeks to address the research question: In children with moderate-to-severe asthma, do intravenous magnesium infusions added to standard Pediatric intensive care unit (PICU)-level…
- Trial name
- NCT01522040
- Testing
- Magnesium Sulfate
- Where
- United States
- Sponsor
- University of Louisville
Pediatric Obesity, Asthma in Children
Steroid Metabolism in Obese and Non-Obese Pediatric Patients Hospitalized for Status Asthmaticus
Single center, open-label, non-randomized study to assess the pharmacokinetic profile of methylprednisolone in healthy children 2-20 years of age admitted for asthma exacerbation.
- Trial name
- NCT04874610
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Asthma, Dermatitis, Atopic
A Long-Term Examination of Asthma From Childhood Through Adolescence
Asthma is a common disease that is often diagnosed in childhood. In some teenagers, asthma symptoms disappear and treatment can be stopped; however, for some of these people, asthma symptoms return in adulthood.
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Urticaria
- Trial name
- NCT00541255
- Where
- United Kingdom
- Volunteers
- 1,313 people, healthy volunteers welcome
- Sponsor
- Isle of Wight NHS Trust
Asthma in Children, Rehabilitation
Exercise Rehabilitation for Children With Asthma
Asthma, a prevalent chronic condition among children and adolescents, substantially impairs their quality of life. In addressing this significant health concern, this study focuses on the potential of a customized exercise…
- Conditions
- Asthma in Children, Rehabilitation, Exercise
- Trial name
- NCT06272604
- Testing
- Personalized Exercise Rehabilitation
- Volunteers
- 100 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Asthma in Children
Oral Health Status of Asthmatic Children
This study aimed to investigate the dental caries experience, periodontal health and salivary properties of asthmatic and non-asthmatic children ⁄ adolescents.
- Trial name
- NCT04388098
- Testing
- Diagnosis of caries experience and periodontal health
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Trakya University
Asthma, Childhood Asthma
Childhood Asthma Perception Study
This randomized controlled trial will include Latino and Black adolescents with asthma ages 10-17 years old and their caregivers. Participants will be recruited from clinics in the Bronx, New York.
- Trial name
- CAPS (NCT02702687)
- Testing
- PEF Feedback, Control Feedback
- Where
- 2 sites in United States
- Volunteers
- 363 people
- Sponsor
- Albert Einstein College of Medicine
Asthma in Children, Anxiety
Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?
Six studies have preceded this project. Three studies suggested that there is a significant connection between pediatric asthma and disruptions in maternal-infant bonding (Feinberg, 1988; Schwartz, 1988; Pennington, 1991).
- Trial name
- NCT02158338
- Testing
- Asthma, Non-asthma
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ran Anbar
Pediatric Asthma, Uncontrolled Asthma
Systems Pharmacology Approach to Uncontrolled Pediatric Asthma
Background: Asthma is a heterogeneous respiratory disease and the most common chronic disease in children. A small subset of children has continuous poor asthma control despite appropriate adherence to asthma medication.
- Trial name
- NCT04865575
- Where
- 6 sites in Germany, Netherlands and 3 more
- Volunteers
- 145 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Asthma Childhood, Respiratory Muscle Training
Effects of Expiratory Muscle Training in Children With Asthma: A Randomised Controlled Trial
The goal of this randomized clinical trial is to evaluate the effectiveness of expiratory muscle training (EMT) as an adjunct to conventional chest physiotherapy in children with asthma.
- Trial name
- NCT07169071
- Testing
- Home-based chest physiotherapy program, Expiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Asthma Childhood
This Study Aims to Compare Asthma Control in Children Monitored With FeNO Against a Historical Cohort Without FeNO. Secondary Objectives Include Evaluating Associations Between FeNO Levels, ACT/C-ACT Scores, Eosinophil Counts, FEV1%, ICS Adherence, and Exacerbation Frequency.
This study aims to evaluate whether incorporating FeNO monitoring into routine pediatric asthma care improves clinical outcomes relative to a historical cohort managed without FeNO
- Trial name
- NCT07788534
- Testing
- FENO, PFT
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Asthma
Risk Factors for Early Remodelling in Severe Asthma in Children
Background: Asthma is a frequent disease characterized by bronchial hyperresponsiveness, inflammation and remodeling. Consistent epidemiological data indicate that outcome of asthma in adults may be determined in early childhood.
- Trial name
- P'tit-ASTHME (NCT02806466)
- Testing
- Fiberoptic bronchoscopy
- Where
- 2 sites in France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Bordeaux
Diagnosis, Inflammation
Diagnosing Asthma With Clinically Accessible, Non-invasive, and Efficient Tests: a Child-inclusive Translational Investigation
Asthma is a common inflammatory respiratory disease affecting 11% of Canadians, but its diagnosis remains challenging, leading to delays in treatment or overtreatment.
- Conditions
- Diagnosis, Inflammation, Asthma in Children, Asthma
- Trial name
- DIVE 2 (NCT07011394)
- Testing
- FeNO, Blood eosinophil count
- Where
- 3 sites in Canada
- Volunteers
- 123 people
- Sponsor
- Université de Sherbrooke
Asthma in Children
Pediatric Glittre ADL-test in Children With Asthma
The aim of the study is to investigate reliability, validity, of the Glittre ADL Test in children with Asthma.
- Trial name
- NCT03985956
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Asthma in Children
Clinical Pharmacology of CHF 1535 50/6 ug Next DPI in Children 5-11 Years Old
This is a pharmacokinetic comparison of CHF 1535 50/6 NEXT DPI versus the free combination of Beclomethasone DPI and Formoterol DPI in children (5 to 11 years old) of a formulation already approved in adults.
- Trial name
- PAED4 (NCT01468272)
- Testing
- free comb. beclomethasone DPI and formoterol DPI, CHF 1535 50/6 NEXT DPI
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma Acute, Exacerbation of Allergic Asthma
Nebulized Ketamine for Severe Asthma Attacks in Children
This is a double-blinded, randomised, placebo-controlled trial enrolling 60 children aged 1 to 13 years with severe asthma exacerbation. All participants will receive standard therapy.
- Trial name
- NCT07728851
- Testing
- Ketamine (1 mg/kg)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University