Clinical trials: Childhood Asthma
Asthma, Lung Diseases
Childhood Asthma Management Program (CAMP) Phases I (Trial), II (CAMPCS), III (CAMPCS/2), and IV (CAMPCS/3)
The purpose of this study is to evaluate the long term effects of anti-inflammatory therapy compared to bronchodilator therapy on the course of asthma, particularly on lung function and bronchial hyperresponsiveness, and on…
- Trial name
- CAMP (NCT00000575)
- Testing
- Nedocromil, Budesonide
- Volunteers
- 1,041 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Asthma, Childhood Asthma
Childhood Asthma Perception Study
This randomized controlled trial will include Latino and Black adolescents with asthma ages 10-17 years old and their caregivers. Participants will be recruited from clinics in the Bronx, New York.
- Trial name
- CAPS (NCT02702687)
- Testing
- PEF Feedback, Control Feedback
- Where
- 2 sites in United States
- Volunteers
- 363 people
- Sponsor
- Albert Einstein College of Medicine
Asthma
Telephone Coaches to Improve Control of Asthma in Children ( PARTNER) Study)
Parents of children with asthma must work with their child's pediatrician to ensure that their child's asthma is managed well. Asthma coaches are one way to facilitate and support the relationship between parents and…
- Trial name
- PARTNER (NCT00860834)
- Testing
- Asthma Coaching Program, Usual Care
- Where
- United States
- Volunteers
- 984 people
- Sponsor
- Washington University School of Medicine
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Asthma, Acute Asthma
Budesonide Inhalation Suspension for Acute Asthma in Children
The purpose of this study is to determine whether the addition of budesonide inhalation suspension (BIS) to the standard therapy of albuterol, ipratropium bromide, and systemic corticosteroids (SCS) for moderate to severe asthma…
- Conditions
- Asthma, Acute Asthma, Reactive Airway Exacerbation
- Trial name
- NCT00393367
- Testing
- Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg, Prednisolone, prednisone, or methylprednisolone, Albuterol, ipratropium bromide
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Children's Hospital of Philadelphia
Asthma in Children, Children, Adult
Evaluation of the Possible Effect of Inspiratory Muscle Training on Inflammation Markers and Oxidative Stress in Childhood Asthma
As inflammation and oxidative stress increase in asthma patients, the severity of symptoms and clinical findings increase. Therefore, this study was planned to evaluate the possible effect of inspiratory muscle training (IMT) on…
- Trial name
- NCT05296707
- Testing
- Inspiratory muscle training, Used routine medicine, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Ege University
Asthma
Use of Dexamethasone in Pediatric Asthma Exacerbations
The purpose of this study is to compare the efficacy of a single dose of dexamethasone vs. two doses of dexamethasone in mild and moderate asthma exacerbations pediatric patients.
- Trial name
- NCT02192827
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- University at Buffalo
Severe Asthma
Clinico-biological Correlation of Severe Asthma in Children
Asthma is the most common chronic respiratory disorder in children. Despite significant advances in understanding of asthma, available therapies fail to alter the natural history and progression of the disease.
- Trial name
- NCT02038374
- Testing
- biopsies
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Asthma in Children
Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)
The long-term goal is to implement an evidence-based asthma intervention based on the Center for Disease Control's recommended framework (EXHALE) within Baltimore City Public Schools (BCPS).
- Trial name
- NCT05814510
- Testing
- Asthma CHAMPS full program, Asthma CHAMPS Wait List Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Asthma in Children
Personalized Digital Health and Artificial Intelligence in Childhood Asthma
Asthma is a chronic inflammatory disease of the airways that causes recurrent episodes of wheezing, breathing difficulties and coughing.
- Trial name
- Asthmoscope (NCT04528342)
- Where
- 2 sites in Switzerland
- Volunteers
- 290 people
- Sponsor
- Isabelle Ruchonnet-Métrailler
Pediatric Asthma, Maternal Depression
Intervention for Depressed Latina Mothers of Children With Asthma
This study is to develop and pilot test a new group-based intervention for depressed Latina mothers of children with asthma. The investigators ongoing work has identified that close to 50% of Latina mothers of children with…
- Trial name
- MAADRE (NCT01326182)
- Testing
- MAADRE, MAAS
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 114 people
- Sponsor
- Rhode Island Hospital
Asthma in Children
Budesonide/Formoterol Turbuhaler® Versus Terbutaline Nebulization as Reliever Therapy in Children With Moderate Asthma Exacerbation
Combined use of inhaled corticosteroids and long-acting β-agonists (LABAs) as the controller and the quick relief therapy termed single maintenance and reliever therapy (SMART) is a potential therapeutic regimen for the…
- Trial name
- ASTHMAFAST (NCT04705727)
- Testing
- Budesonide Formoterol Drug Combination, nebulisation of terbutaline
- Where
- 8 sites in France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Asthma in Children
AmbuLatory Pediatric Asthma CAre
The ALPACA study has a prospective randomized control interventional design, including a follow-up period to evaluate follow-up effects. The study is divided into two phases of 3 months using eHealth and observational monitoring.
- Trial name
- NCT05517096
- Testing
- E-Health
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Persistent Asthma, Asthma in Children
Asthma Research in Children and Adolescents
The purpose of this study is to assess the evolution of disease control, health-related quality of life, and the risk of severe asthma exacerbations in children and adolescents with persistent asthma in Spain at short, mid and…
- Conditions
- Persistent Asthma, Asthma in Children, Asthma Exacerbation
- Trial name
- ARCA (NCT04480242)
- Testing
- Inhaled Corticosteroids (ICs), Fixed-Dose Combination of Inhaled Corticosteroids and Long- Acting Beta-agonist (ICs/LABA), Other treatments
- Where
- 15 sites in Spain
- Volunteers
- 525 people
- Sponsor
- Parc de Salut Mar
Asthma, Asthma in Children
Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents
Bronchial asthma may present with symptoms other than the commonly reported complaints (cough, chest tightness, shortness of breath and wheezing).
- Conditions
- Asthma, Asthma in Children, Dyspnea, Cough
- Trial name
- NCT06201494
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- Charles University, Czech Republic
Asthma
Progression of Airway Obstruction in Childhood Asthma
Distinct patterns of loss in pulmonary function were identified in children with mild to moderate asthma participating in a 10-year observation period during the NHLBI Childhood Asthma Management Program.
- Trial name
- NCT00873873
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Jewish Health
Asthma, Allergy
Childhood Origins of Asthma (COAST)
Although asthma is likely to be a heterogeneous disease or syndrome, three factors and/or events repetitively emerge for their ability to significantly influence asthma inception in the first decade of life: immune response…
- Trial name
- COAST (NCT00204841)
- Where
- United States
- Volunteers
- 287 people
- Sponsor
- University of Wisconsin, Madison
Asthma in Children
Determinants of Functional Capacity in Children With Asthma
The primary aim of this study is to compare the respiratory function, respiratory muscle strength, functional capacity, and lower extremity strength of children with asthma and healthy children in the same age group.
- Trial name
- NCT05963919
- Testing
- 6-minute walk test, Pulmonary function test, Respiratory muscle strength test
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atlas University
Asthma
Imperial County Asthma CER Project: Respira Sano
The immediate goal of the Imperial County CER Asthma project is to identify strategies to improve asthma control among children 0-17 years old and the asthma control behaviors of their families, their health care providers, and…
- Trial name
- Respira Sano (NCT02768883)
- Testing
- Respira Sano
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- San Diego State University
Asthma, Sleep
Sleep Quality in High School Students With Asthma - II
The overall goal of this project is to develop and to preliminarily validate a novel intervention to be delivered in the high school setting that integrates two evidence-based, school-based interventions for urban adolescents…
- Conditions
- Asthma, Sleep, Asthma in Children
- Trial name
- NCT03329066
- Testing
- MAST - Managing Asthma & Sleep in Teens, ASMA - Asthma Self-Management for Adol, Information & Referral Control Group
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Columbia University