Clinical trials: Childhood Autism
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
ADNP, Helsmoortel-Van Der Aa Syndrome
ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20.
- Conditions
- ADNP, Helsmoortel-Van Der Aa Syndrome, Autism Spectrum Disorder
- Trial name
- NCT03718936
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder, Autism
Halliwick Hydrotherapy and Snoezelen
The aim of this study was to evaluate the effectiveness of the Halliwick concept in the adapted Snoezelen multi-sensory environment, in the gross mobility of children belonging to the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Autism, Sensory Disorder
- Trial name
- NCT05134844
- Testing
- Hydrotherapy- Snoezelen, Snoezelen
- Where
- Greece
- Volunteers
- 53 people
- Sponsor
- University of Thessaly
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 7, who have been diagnosed with moderate to severe autism.
- Trial name
- NCT06359080
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder, Child Development Disorders, Pervasive
Trial of Therapeutic Horseback Riding in Children and Adolescents With Autism Spectrum Disorder
This study is being carried out to learn more about the effects of Therapeutic Horseback Riding (THR) for children and adolescents with an autism spectrum disorder (ASD).
- Trial name
- NCT02301195
- Testing
- Therapeutic horseback riding, Barn Activity Intervention
- Volunteers
- 209 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
Relationships, Employment, Autonomy, and Life Satisfaction (REALS) Study
One of the major methodological obstacles to more informed policies and programs to support the successful transition to adulthood in autism spectrum disorder (ASD) is the absence of suitable measures of meaningful outcomes for…
- Trial name
- REALS (NCT04381195)
- Testing
- REALS Development, REALS Testing
- Where
- United States
- Volunteers
- 1,650 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Evaluation of Serum Adrenal Androgens Among Prepubertal and Pubertal Boys With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder of unclear etiology. There are theories depicting the importance of sex steroid hormones in autism, since the prevalence of the disorder is male-biased.
- Trial name
- NCT05811507
- Testing
- serum total testosterone, serum androsterone, serum androstenedione and serum dehydroepiandrosterone sulfate, The Childhood Autism Rating Scale (CARS), DSM-5 Diagnostic Criteria for ASD
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Psychological Distress, Stress, Psychological
ASD (Autism Spectrum Disorder) Telehealth for Distress Related to COVID-19
The purpose of this study is to evaluate the feasibility, acceptability and effectiveness of a brief, telehealth intervention (the Emotional Support Plan), intended to support autistic adults to cope with their negative emotions…
- Conditions
- Psychological Distress, Stress, Psychological, Autism Spectrum Disorder
- Trial name
- NCT04460677
- Testing
- Emotional Support Plan, Daily Monitoring
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Vestibulo-Ocular Reflex for Balance and Stimming in Autism Spectrum Disorder
Autism spectrum disorder is a neurodevelopmental disorder that encompasses a number of disorders specifically affecting social skills, Communication and present with Rapid repetitive behaviors.
- Trial name
- NCT06340139
- Testing
- conventional treatment, experimental treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Irritability Associated With Autism Spectrum Disorder (ASD)
Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder
The purpose of this study is to find out about the potential benefits and safety of brexpiprazole in children and adolescent participants, aged 5 to 17, with irritability associated with autism spectrum disorder.
- Trial name
- NCT04174365
- Testing
- Brexpiprazole
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
Autism Spectrum Disorder
Social Groups for Australian Children on the Autism Spectrum
This study evaluates the KONTAKT social skills group training in Australian children on the autism spectrum compared to an active control group which is a group Art class
- Trial name
- NCT04024111
- Testing
- KONTAKT(c), Art group
- Where
- Australia
- Volunteers
- 84 people
- Sponsor
- Curtin University
Autism Spectrum Disorder
Active Ingredients & Efficacy of Aquatic Therapy for Autistic Children
Accidental drowning is the number one cause of death in children with autism spectrum disorders (ASD) and highlights the critical need for swim lessons and water safety training for this population.
- Trial name
- NCT05524753
- Testing
- AquOTic
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Autism Spectrum Disorder, Disruptive Behaviours
Feasibility Study on Parents Skill Training Program for Reducing Parental Distress and Disruptive Behavior of Their Children With Autism Spectrum Disorder (ASD)
Children with Autism Spectrum Disorder (ASD) usually exhibt problematic behavioral issues such as hitting, non-compliance, tantrums, spitting, headbanging and aggression, this not only cause distress for the child but also has a…
- Trial name
- NCT04339153
- Testing
- Parent Training for Disruptive Behaviours
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Autism Spectrum Disorder
School-Age Children With Autism With Limited Expressive Language Skills
This project will address a major challenge to the field of autism research: improving expressive communication in children with autism who have reached school age but have not acquired functional spoken language (non-verbal…
- Trial name
- NCT01529580
- Testing
- Non-Verbal School Aged Children with Autism (NVSACA) Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder (ASD)
Evaluation of a Clinical Transitional Program in Autism
Clinical trial without drug, randomized: Comparison of a specific and integrative clinical protocol for young adults with autism to usual treatment. It will include both low and high-functioning participants.
- Trial name
- TAVA (NCT03392870)
- Testing
- Integrative interventional programme, As usual
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Corporacion Parc Tauli
Autism Spectrum Disorder, Autism
Project AFECT (Autism Family Empowerment Coaching and Training Program)
The goal of this clinical trial is to learn about the journey of families after their child's diagnosis of autism and to help parents understand autism and get the right treatments for their child.
- Conditions
- Autism Spectrum Disorder, Autism, Autism Spectrum Disorders, Autistic Disorder
- Trial name
- AFECT (NCT05910502)
- Testing
- Autism Family Empowerment Coaching and Training Program
- Where
- 2 sites in United States
- Volunteers
- 143 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Dialectic Behaviour Therapy (DBT) for People With Autism: A Multiple Baseline Single Case Design
The goal of this experimental study is to test the effectiveness of Dialectic Behavioural Therapy in patients with Autism Spectrum Disorder. The aim questions are: 1.
- Trial name
- DGT-ASS (NCT07786883)
- Testing
- Dialectic Behavioural Therapy
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- GGZ Friesland
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