Clinical trials: Childhood Autism
Autism Spectrum Disorder (ASD), Autism
An Open-Label Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
The purpose of this study is to evaluate the safety and tolerability of memantine in pediatric (6-12 years old) patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and…
- Conditions
- Autism Spectrum Disorder (ASD), Autism, Autistic Disorder, Asperger's Disorder
- Trial name
- NCT01592786
- Testing
- Memantine Hydrochloride (HCl)
- Where
- 118 sites in United States, Australia and 16 more
- Volunteers
- 906 people
- Sponsor
- Forest Laboratories
Autism, Autism Disorders and Maternal Stress
Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
This study aims to evaluate the impact of a sensory-adapted dental environment (SADE) on the stress levels and behavioral responses of children with autism spectrum disorder (ASD) during dental visits.
- Conditions
- Autism, Autism Disorders and Maternal Stress, Sensory Integration Disorder, Stress Biomarkers
- Trial name
- SMILED (NCT07887243)
- Testing
- Sensory-Adapted Dental Environment
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Developmental, Behavioral and Mental Health, Adhd
Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas
In partnership with a multi-site, Los Angeles-area community clinic consortium, North East Valley Health Corporation (NEVHC), the investigators will use telehealth to integrate pediatric developmental, behavioral and mental…
- Conditions
- Developmental, Behavioral and Mental Health, Adhd, Depression, Anxiety
- Trial name
- NCT02396576
- Testing
- Telehealth Intervention
- Where
- 6 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
A Study of Mesenchymal Stem Cell in the Treatment of Autism Spectrum Disorder
This clinical trial aims to evaluate the safety and preliminary efficacy of intravenous administration of human bone marrow-derived mesenchymal stem cells (hBMMSCs) in patients with autism spectrum disorder (ASD).
- Trial name
- ASD (NCT07177677)
- Testing
- hBMMSC
- Volunteers
- 42 people
- Sponsor
- Jiuzhitang Maker (Beijing) Cell Technology Co.,Ltd.
Autism Spectrum Disorders, Schizophrenia
Visual Exploration and Attention: Studies in Patients With Schizophrenia and Autism Spectrum Disorders
The aim of the protocol is to better understand the impairments in visual processing, as such impairments may induce social interaction difficulties in subjects with autism spectrum disorders (adults and children) and…
- Trial name
- NCT00914030
- Testing
- Neuropsychological evaluation
- Where
- 5 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Autism Spectrum Disorder
Pimavanserin for Rigid-compulsive Symptoms in Autism Spectrum Disorder
This Phase 2 study examines the safety, tolerability, and preliminary efficacy of pimavanserin in individuals with Autism Spectrum Disorder.
- Trial name
- NCT05999240
- Testing
- Pimavanserin Tartrate 34 Mg ORAL CAPSULE [NUPLAZID]
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Healthy Volunteer, Autistic Disorder, Asperger's Syndrome
A Non-Drug Study on the Relationship Between Exploratory Biomarkers and Functional Dimensions in Individuals With Autistic Disorder or Asperger's Syndrome
This multi-center, non-drug study will explore the relationship between exploratory biomarkers and functional dimensions in male adult individuals with Autistic Disorder or Asperger's Syndrome and healthy volunteer controls.
- Trial name
- NCT01669889
- Where
- 3 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder
Ayres Sensory Integration in Preschool Children With Autism Spectrum Disorder
This study evaluates the effectiveness of occupational therapy using Ayres Sensory Integration® (ASI) in preschool children with autism spectrum disorder (ASD).
- Trial name
- NCT07507630
- Testing
- Ayres Sensory Integration, Usual Care
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Medipol University
Attention Deficit Hyperactivity Disorder (ADHD), Autism
The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine
The investigators are conducting a 10-week brain imaging and medication study. They are doing the research to study the response of Attention-Deficit/ Hyperactivity Disorder (ADHD) in youth with Autism Spectrum Disorder (ASD) on…
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Autism, Autism Spectrum Disorder
- Trial name
- NCT06853665
- Testing
- Adderall XR (mixed salts amphetamine)
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Gagan Joshi
15q Duplication Syndrome, CDKL5 Deficiency Disease
A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)
The purpose of this study is to investigate the effect of soticlestat on the frequency of motor seizures for participants with Dup15q or CDD during the Maintenance Period.
- Trial name
- NCT03694275
- Testing
- Soticlestat
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- Takeda
Autism Spectrum Disorder
Study to Evaluate the Janssen Autism Knowledge Engine in Children and Adults With Autism Spectrum Disorder
The purpose of this study is to assess the usability of the Janssen Autism Knowledge Engine (JAKE) as a system to monitor clinical outcomes in autism spectrum disorder (ASD) (severe abnormalities in the development of many basic…
- Trial name
- Mentis (NCT02299700)
- Testing
- No Intervention
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Janssen Research & Development, LLC
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Neurodevelopmental Disorders, Autism
Early Life Anemia and Children's Risk of Neurodevelopmental Disorders: National and Regional Register-based Studies
The overall project aim is to study children's neurodevelopmental outcomes (including diagnoses of autism, ADHD, and intellectual disability) following exposure to maternal anemia during pregnancy or anemia during the first year…
- Conditions
- Neurodevelopmental Disorders, Autism, ADHD, Intellectual Disability
- Trial name
- NCT06199362
- Where
- Sweden
- Volunteers
- 2,400,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder (ASD, Parental Behaviors
Effectiveness of Video-feedback for Positive Parenting with Children At Risk of ASD
Improving parent-child interactions benefits child development and parents' perception of their competencies for childrearing and support for child learning and development, which in turns positively impacts on parental emotional…
- Trial name
- VIFEPOPA (NCT06604988)
- Testing
- Video-feedback intervention to promote positive parenting
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Barcelona
Attention Deficit Disorder With Hyperactivity, Autistic Disorder
Methylphenidate in Children and Adolescents With Pervasive Developmental Disorders
This study will evaluate the efficacy and safety of methylphenidate for treating hyperactivity, impulsiveness, and distractibility in 60 children and adolescents with Pervasive Developmental Disorders (PDD).
- Conditions
- Attention Deficit Disorder With Hyperactivity, Autistic Disorder, Pervasive Development Disorders
- Trial name
- NCT00025779
- Testing
- methylphenidate, guanfacine
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Comparsion of SPARK and Fundamental Motor Training
It was a Randomized Clinical Trial.Data will be collected from Life care rehabilitation and special child facility.The study was completed within 6 months after approval of synopsis.The calculated sample size, through WHO sample…
- Trial name
- NCT05986760
- Testing
- SPARK
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- khadija liaquat
Autism Spectrum Disorder
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
An MRI Study in Subjects with Autism Spectrum Disorder and Subjects with Food Addictive Disorder compared to healthy volunteers.
- Trial name
- RESYSTAA (NCT05391113)
- Testing
- MRI, EEG
- Where
- 3 sites in France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder
Open Label Phase I hCT-MSC in Toddlers With Autism Spectrum Disorder
This is a single site, prospective study of one intravenous infusion of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) in toddlers with autism spectrum disorder (ASD).
- Trial name
- TACT (NCT04294290)
- Testing
- hCT-MSC infusion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Autism Spectrum Disorder
Social Skills Training Group Effectiveness in Adolescents With Autism Spectrum Disorder
Autism spectrum disorders (ASD) is a neurodevelopmental disorder characterized by persistent deficits in social communication and social interaction across multiple contexts, and the presence of restricted, repetitive behavior…
- Trial name
- NCT05857813
- Testing
- Program for the Education and Enrichment of Relational Skills (PEERS®)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Autism
Effect of Milk Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Children With Autism
The purpose of this study is to determine the tolerability of dietary supplements and if these supplements can promote a healthy bacterial environment in the intestines of children with autism spectrum disorders and…
- Trial name
- NCT02086110
- Testing
- Synbiotic, Prebiotic
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of California, Davis
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