Clinical trials: Childhood Autism
Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD)
Physiotherapy for Improving Mental Health in Children and Adolescents With ASD and ADHD
This study investigates whether a structured physiotherapy program can help reduce symptoms of stress, anxiety, and depression in children and adolescents diagnosed with Autism Spectrum Disorder (ASD) or…
- Conditions
- Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Neurodevelopmental Disorders
- Trial name
- NCT07231354
- Testing
- Structured Physiotherapy Program
- Where
- Greece
- Volunteers
- 117 people
- Sponsor
- International Hellenic University
Autism Spectrum Disorder
Improving Driving in Young People With Autism Spectrum Disorders
This study will examine the effects of treatment with the anti-anxiety medicine buspirone on driving performance (eye tracking) in individuals with high-functioning autism spectrum disorder (HF-ASD).
- Trial name
- NCT03538431
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Improving Outcomes in Autism: Community Implementation of Stepped Transition in Education Program
The goal of this study is to conduct the first community-based implementation of the STEPS program and test feasibility and preliminary impact.
- Trial name
- NCT05581069
- Testing
- STEPS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama, Tuscaloosa
Autism, Gastrointenstinal Symptoms
Mycobiome Evaluation in Children With Autism & GI Symptoms
This study's primary aim is to explore the potential differences in the gut mycobiome of children with autism spectrum disorder compared to otherwise healthy children.
- Trial name
- NCT03494088
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism
Treatment for Children With Autism and Anxiety
Children with high-functioning autism spectrum disorders (ASD) are at high risk for developing significant anxiety symptoms. Cognitive behavior therapies (CBT) are frequently used for children with anxiety symptoms with good…
- Trial name
- NCT01727466
- Testing
- Facing Your Fears
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
Extension for Community Healthcare Outcomes Autism Replication Evaluation
ECHO Autism was intended to assess rigorously the impact of a 12-session telemedicine training program on participating Primary Care Providers (PCP) knowledge, clinical behavior, and self-efficacy in the screening and care of…
- Trial name
- ECHO Autism (NCT03677089)
- Testing
- 12 ECHO Autism telehealth clinics
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
An Exploratory Open Label Study of EPI-743 (Vincerinone TM) in Children With Autism Spectrum Disorder
The investigators hypothesize that EPI-743 may provide clinical benefit to children with Autism Spectrum Disorder.
- Trial name
- Autism (NCT02226458)
- Testing
- EPI-743
- Sponsor
- Edison Pharmaceuticals Inc
Autism Spectrum Disorder
Effectiveness of a Parent-mediated Intervention With PACT on Children With ASD
Autism Spectrum Disorder (ASD) is a neuro-developmental disorders. There are different types of interventions. Among these interventions Early Start Denver Model (ESDM) and Preschool Autism Communication Therapy (PACT) have…
- Trial name
- IFPAD (NCT04244721)
- Testing
- Preschool Autism Communication Therapy (PACT), Treatment As Usual (TAU)
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Hôpital le Vinatier
Autism
A Trial of CM-AT in Children With Autism
The purpose of this study is to determine whether CM-AT is safe and effective in treating the core symptoms of autism.
- Trial name
- CM-AT (NCT00881452)
- Testing
- CM-AT
- Where
- 19 sites in United States
- Volunteers
- 182 people
- Sponsor
- Curemark
Autism Spectrum Disorder, Autism
Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children
This study will examine the potential effectiveness of a virtually delivered parent-mediated intervention for insistence on sameness behaviors in autism and investigate 1) whether caregivers can learn to deliver the adapted…
- Trial name
- NCT06472115
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE) for insistence on sameness (IS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autistic Disorder
Pivotal Response Group Treatment for Parents of Young Children With Autism
This is a research study examining the effectiveness of pivotal response treatment group (PRTG) in targeting language skills in young children with autism.
- Trial name
- PRTG (NCT01881750)
- Testing
- Pivotal Response Training (PRT), Parent Education Group (PEG)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Stanford University
ADHD, Autism
Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
A study to assess pharmacokinetics, safety and tolerability of brexpiprazole in children ages 6 to <13 years with CNS disorders.
- Conditions
- ADHD, Autism, Bipolar I Disorder, Conduct Disorder
- Trial name
- NCT03292848
- Testing
- Brexpiprazole
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism Spectrum Disorder
e-GOLIAH in Autistic Spectrum Disorders
Randomized open-label study comparing children aged 3 to 6 years with autism and normal cognitive development or mild cognitive impairment receiving the usual treatment plus intensive use of eGOLIAH (experimental group) with…
- Trial name
- e-GOLIAH-ECO (NCT05271955)
- Testing
- "e-GOLIAH", Usual care
- Where
- 12 sites in France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Emotion Regulation
Evaluating Additive Effects of Including Canines in Regulating Together
The primary objective is to evaluate the potential additive effect of animal-assisted intervention (AAI) on a manualized behavioral treatment targeting emotion dysregulation (ED) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05803343
- Testing
- Regulating Together-Canine, Regulating Together-Standard
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder (ASD), Neurotypical
Course of Face-to-face Interactions in Adults With Autism
This research explores how adults with autism make eye contact during formal and informal interactions; to what extent the nature of a conversation influences how eye contact is made in terms of length, frequency and overall…
- Trial name
- NCT06925308
- Testing
- Conversation
- Where
- Netherlands
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05664789
- Testing
- N acetyl cysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Rett Syndrome
A Safety Study of NNZ-2566 in Patients With Rett Syndrome
The purpose of this study is to determine whether NNZ-2566 is safe and well tolerated in the treatment of Rett Syndrome in adolescent and adult females.
- Trial name
- NCT01703533
- Testing
- NNZ-2566
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Neuren Pharmaceuticals Limited
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
Autism Spectrum Disorder
Stimulus-Stimulus Pairing Study
The purpose of the current study is to deliver the SSP procedure to children diagnosed with autism that do not have vocal language. The study will also aim to gather data in the natural environment using a voice recorder.
- Trial name
- NCT02464527
- Testing
- Stimulus-stimulus pairing, Vocal recorder
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University
Children With Autism Spectrum Disorder
The Effects of Physical Activity Program on Psychomotor and Psycho-Social Characteristics of Autistic Children
The aim of this study was to examine the effect of Physical Activity Program (PAP) on psychomotor and psychosocial characteristics of autistic children.
- Trial name
- NCT07273240
- Testing
- Physical Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
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