Clinical trials: Childhood Autism
Autism
FLIGHT - Autism: Education and Health Coaching Program Focused on Modifiable Lifestyle Factors for Parents
The primary purpose of this study is to evaluate the feasibility and effectiveness of an education and coaching program for parents of children with newly diagnosed autism that is focused on modifiable lifestyle factors and…
- Trial name
- NCT07375537
- Testing
- Parent education and coaching program for newly diagnosed autism
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Documenting Hope Project
Autism Spectrum Disorder
Influence of Rhythm and Interpersonal Relationship on Gait Parameters in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is associated with differences in social communication, motor coordination, interpersonal synchronization, and gait.
- Trial name
- NCT06659328
- Testing
- Structured Walking Intervention for Children with Autism Spectrum Disorder.
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Europea de Madrid
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
A Machine Learning Approach for Predicting tDCS Treatment Outcomes of Adolescents With Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behaviors.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography, Machine Learning
- Trial name
- NCT05035511
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Single Session Support for Parents of Children With Neurodevelopmental Disabilities Struggling With Anxious Avoidance
This study will inform the development of a brief online program to help parents better understand and respond to anxiety-related behaviors in children with neurodevelopmental disorders (NDDs) such as autism spectrum disorder…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), Intellectual Disability
- Trial name
- EMPOWER-ND (NCT07898592)
- Testing
- EMPOWER-ND
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder
A Clinical Trial of a New Computer Based Intervention for Children With Autism.
The CLICK-EAST research project is an investigation of the efficacy of a computer based learning programme which aims to teach the fundamental components of social attention to young children with autism spectrum disorder (ASD).
- Trial name
- Click-East (NCT01493609)
- Testing
- Click-East app
- Where
- 2 sites in United Kingdom
- Volunteers
- 54 people
- Sponsor
- University of Edinburgh
Autism Spectrum Disorder
Investigating Social Competence in Youth With Autism
Our treatment, SENSE Theatre, combines several well-documented, effective behavioral strategies and theatre techniques. The proposed project will extend previous findings showing improving improvement in memory for faces.
- Trial name
- NCT03368001
- Testing
- SENSE Theatre, Tackling Teenage Together
- Where
- 3 sites in United States
- Volunteers
- 318 people
- Sponsor
- Vanderbilt University Medical Center
Autism, Autism Spectrum Disorder
A Kinematic Analysis of Motor Planning and Movement Execution of Children With Autism Spectrum Condition
Autism Spectrum Condition (ASC) is a behavioral syndrome characterized by a severe organizational disorder of thinking and major functions that regulate human adaptation.
- Trial name
- NCT06144775
- Testing
- Kinematics measures
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder
A Study to Evaluate the Efficacy and Safety of AST-001 in ASD Children
1. Study purpose: To demonstrate the superiority of AST-001 compared to placebo in improving core symptoms of autism spectrum disorder (ASD) in children with ASD. 2.
- Trial name
- NCT06333964
- Testing
- AST-001
- Where
- 11 sites in South Korea
- Volunteers
- 169 people
- Sponsor
- Astrogen, Inc.
Autism or Autistic Traits
Autism Caregiver Coaching in Africa
Around the world there is a growing need to develop early intervention services in local communities that support a better quality of life for all autistic people.
- Trial name
- ACACIA (NCT05551728)
- Testing
- ESDM-informed caregiver coaching
- Where
- South Africa
- Volunteers
- 320 people
- Sponsor
- Duke University
Autism Spectrum Disorder
/Autism Spectrum Disorder(ASD)Hearing Abnormalities Study
Co morbidity rates of hearing loss in children with autism spectrum disorder are high and increasing. Investigators are aiming to: 1.
- Trial name
- NCT03252392
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Autism Spectrum Disorder
Autism, Emotional Processing, and the Amygdala
Empathy imbalance hypothesis suggests that individuals with autism Spectrum Disorder (ASD) should have a deficit of cognitive empathy and a surfeit of emotional empathy.
- Trial name
- NCT04549506
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yawei Cheng
Autism Spectrum Disorder, Parents
Mindfulness Training and Parent-coaching Interventions for Autism Spectrum Disorder
Caregivers of children with autism spectrum disorder (ASD) report higher levels of depression and distress than caregivers of typically developing children as well as children with other developmental disabilities.
- Conditions
- Autism Spectrum Disorder, Parents, Stress
- Trial name
- NCT03889821
- Testing
- Parent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Vanderbilt University Medical Center
Autism
Safety of L1-79 in Adolescent and Adult Males With Autism
This is a five-arm designed to assess the safety of L1-79 that incorporates 15 prospectively randomized, placebo controlled patients and 5 open label patients at either 100 tid (three times daily) or 200 tid dosing for 28 days.
- Trial name
- NCT02947048
- Testing
- L1-79
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Yamo Pharmaceuticals LLC
Encopresis, Autistic Disorder
An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders
The purpose of this study is to try to treat bowel movement (BM) accidents differently with children with autism spectrum disorder (ASD). The study will use over-the-counter (OTC) medications to evoke predictable bowel movements.
- Trial name
- NCT02383758
- Testing
- Glycerin Suppository, Bisacodyl suppository, Senna
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Autism Spectrum Disorder
Comparing Behavioral Assessments Using Telehealth for Children With Autism
The main purpose of this study is to determine the most efficient way for families to reduce problem behavior in their children with an autism spectrum disorder.
- Trial name
- NCT02456298
- Testing
- Standard FA+FCT, Pragmatic FA+FCT
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
Autism Spectrum Disorder
Promoting Communication in Minimally Verbal Autistic Children with Social Robot
Minimally verbal (MV) children with Autism Spectrum Disorder (ASD) face significant challenges in communication and social interaction, which are fundamental to learning and development.
- Trial name
- NCT06805916
- Testing
- NAO-Assisted Therapy, Standard therapeutic
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism Spectrum Disorder, Autism
Pepea Pamoja: Cluster-Randomized Trial for Caregivers of Children With Autism in Kenya
Pepea Pamoja is a ten-session, group-based caregiver intervention designed to improve caregiver well-being and strengthen caregivers' ability to support communication and positive behavior in children with autism.
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- NCT07259044
- Testing
- Professionally-facilitated groups, Peer-facilitated groups
- Where
- Kenya
- Volunteers
- 240 people
- Sponsor
- Indiana University
Neurodevelopmental Disorders, Autism Spectrum Disorder
Early Recognition and Intervention in Siblings at High-risk for Neurodevelopmental Disorder
H1The primary goal of this intervention study is to learn if very early parent-mediated intervention in children at risk for neurodevelopmental disorders in the first year of life can be implemented in routine care, positively…
- Trial name
- ERI-SIBS (NCT06512649)
- Testing
- Early intervention, Active monitoring
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Autism Spectrum Disorder, Gastrointestinal Dysfunction
ASC - Autism Study
The ASC - Autism Pilot Study is a single center randomized open dose titrating phase I clinical intervention pilot trial with the aim of investigating safety and treatment effect of an allogeneic adipose tissue derived…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Dysfunction, Leaky Gut Syndrome, Mesenchymal Stromal Cells
- Trial name
- NCT05602116
- Testing
- Adipose tissue derived mesenchymal stromal/stem cells (Cell2Cure®)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Cell to Cure ApS
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