Clinical trials: Childhood Autism
Autism Spectrum Disorder, Anxiety
taVNS for Anxiety in ASD
Investigators will recruit up to 10 patients with Anxiety comorbid with Autism Spectrum Disorder (ASD) from the outpatient clinics at MUSC.
- Trial name
- NCT06258590
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Eating Disorders
Eating Disorders and Autism Spectrum Disorders
This is an observational study where patients with eating disorders (ED) are compared with healthy controls without eating disorder (HC) regarding eating disorders features and autism spectrum features.
- Trial name
- NCT04564170
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Autism Spectrum Disorder
The Effectiveness of OT-ParentShip on Parental Resilience and Functioning of Adolescents With High Functioning Autism
The goal of this clinical trial is to evaluate the efficacy of the OT (Occupational Therapy)-ParentShip intervention program for parents of adolescents with Autism. A mixed method, two group, randomized controlled trial (RCT).
- Trial name
- NCT05879705
- Testing
- Parent intervention
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Autism Spectrum Disorder, Anxiety Disorders
DINO RCT - Treating Anxiety in Children With Autism
Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive…
- Trial name
- NCT06066983
- Testing
- DINOSAUR, Psychoeducation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder
Reducing Challenging Behaviors in Children With Autism Through Digital Health
School-based behavioral approaches to managing challenging behaviors in children with ASD are limited by three key factors: 1) children with ASD often have difficulties communicating their emotions; 2) it is challenging to…
- Trial name
- NCT05277194
- Testing
- KeepCalm app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
Community-based Adaptive Autism Intervention for Toddlers
The proposed study (CAIT: Community-based Adaptive Autism Intervention for Toddlers) aims to determine the most optimal sequence of interventions for improving the social- communicative, language and cognitive outcomes of…
- Trial name
- CAIT (NCT04283045)
- Testing
- JASPER, JASPER Plus+
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Acupressure and Acupuncture as an Intervention With Children With Autism II
The purpose of this study is to see if children with autism spectrum disorder (ASD) will tolerate an acupressure and acupuncture intervention twice weekly over a 3 month period of time that targets regulatory and behavioral…
- Trial name
- NCT00935701
- Testing
- Acupressure and Acupuncture
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autism
Efficacy and Safety of Lenalidomide for Treatment of Autistic Spectrum Disorders
The purpose of this study is to determine if lenalidomide (Revlimid®)reduces proinflammatory cytokines including TNF-alpha and may actually alter the clinical course of autism for some children.
- Trial name
- NCT00996931
- Testing
- lenalidomide
- Volunteers
- 6 people
- Sponsor
- Sutter Medical Foundation
Autism Spectrum Disorder
Virtual Reality-Based Self-Modeling Intervention for Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impairments in social communication and interaction, as well as restricted and repetitive behaviors.
- Trial name
- OSB-VR (NCT07505901)
- Testing
- Virtual Reality Self-Modeling Training, Conventional Behavioral Rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Inonu University
Autism Spectrum Disorder, Developmental Delay
Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of Autism Spectrum Disorder
Caregiver coaching will be provided using telehealth technology, in order to determine the efficacy and effectiveness of the telehealth medium of intervention delivery for caregivers of infants with concern for ASD.
- Trial name
- NCT03592654
- Testing
- infant telehelp
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, Autism
Multisensory Environment Room in Children With Autism Spectrum Disorder
To investigate the effect of multisensory environment room on behavior in children with autism spectrum disorder age 3-5 years old. The children will be randomized into 2 groups: the experimental and the control group.
- Trial name
- NCT05752994
- Testing
- Training in the multisensory room environment, Home program
- Where
- 2 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Autism Spectrum Disorder, EEG With Periodic Abnormalities
Safety and Efficacy of tPBM for Epileptiform Activity in Autism
For this study, the proposed intervention will be noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM) - to the brains of autistic children with abnormal EEGs with epileptiform discharges or…
- Conditions
- Autism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental Disorders
- Trial name
- tPBM (NCT06352372)
- Testing
- noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Richard Frye
Autistic Disorder, Autism Spectrum Disorder
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants
This study will evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single- and multiple-ascending doses (SAD (Part 1) and MAD (Part 2)) and food effect (FE) of RO6953958 following oral…
- Conditions
- Autistic Disorder, Autism Spectrum Disorder, Child Development Disorders, Pervasive, Mental Disorders
- Trial name
- NCT04475848
- Testing
- RO6953958, Midazolam
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorders
Osteopathic Manual Medicine Treatment in Autism
The purpose of this study is to determine how osteopathic manual medicine (OMM) will affect core autism features including social and communication deficits.
- Trial name
- OMMA (NCT01676389)
- Testing
- Osteopathic Manual Medicine (Body Therapy)
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- New York Institute of Technology
Autism
Fluvoxamine and Sertraline in Childhood Autism - Does SSRI Therapy Improve Behaviour and/or Mood?
The purpose of this study is to determine if fluvoxamine or sertraline reduce the fequency or severity of aggressive behaviour, obsessive symptoms, or anxiety in young children with autism.
- Trial name
- NCT00655174
- Testing
- fluvoxamine, sertraline
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- The Hospital for Sick Children
Neurodevelopmental Disorders, Autism
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
There are currently no approved medications for the treatment of anxiety in children and youth with neurodevelopmental disorders (NDDs), both common and rare.
- Conditions
- Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
- Trial name
- CALM (NCT06081348)
- Testing
- Sertraline
- Where
- 7 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Heart Voice: Starry Journey - A Digital ACT Intervention for ASD Caregivers
The goal of this clinical trial is to evaluate the effectiveness of the "Heart Voice: Starry Journey" program, a family-centric and Acceptance and Commitment Therapy (ACT)-based digital narrative intervention, in improving…
- Trial name
- NCT07319455
- Testing
- ACT-Based Mobile Application Intervention
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Harbin Medical University
Autism Spectrum Disorder
The Effectiveness of Group Interpersonal Synchrony in Young Autistic Adults' Work Environment
Background: Few autistic adults are able to integrate successfully into the world of work given their difficulties adapting to the social and stressful aspects of work environments.
- Trial name
- NCT05846308
- Testing
- Structured synchronous physical training, Structured non-synchronous physical training
- Where
- Israel
- Volunteers
- 57 people
- Sponsor
- University of Haifa
Autism Spectrum Disorder, Anxiety
The Effects of Exercise in Anxiety in Children With ASD
This study will examine the effects of a school based exercise programme on anxiety and behaviour levels in children with autism.
- Conditions
- Autism Spectrum Disorder, Anxiety, Behavior
- Trial name
- NCT03860389
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South East Technological University
Autism Spectrum Disorder
Person-Centered Assessment and Monitoring Systems
The proposed study will include an analysis of data for residents of Pennsylvania who are age 21 and older, have a diagnosis of Autism Spectrum Disorder (ASD), and are enrolled in the Commonwealth's Adult Community Autism Program…
- Trial name
- PCAMS (NCT03019978)
- Testing
- PCAMS assessments
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
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