Clinical trials: Childhood Autism
Autism Spectrum Disorder
Application of Esketamine in Anesthesia of Autism Children
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. Autistic children appear with significant frequency for medical services, lots of which requiring procedural sedation or anaesthesia.
- Trial name
- NCT05960942
- Testing
- propofol combined with esketamine, propofol-sufentanil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Autism Spectrum Disorder
Understanding the Mechanisms of Autism : an MRI and Social Cognition Study
The main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties…
- Trial name
- ECLAT (NCT06334588)
- Testing
- MRI, Eye-tracking, Clinical Scales
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Dance, Yoga, And Mindful Movement Training For ASD
The goal of this study is to learn if a dance, yoga, and mindful movement program can improve the lives of adults with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism
- Trial name
- NCT07758088
- Testing
- Yoga, dance and Mindful Movement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- USC Glorya Kaufman School of Dance
Autism Spectrum Disorder
Autism Access Link for Early Referral and Treatment
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- Autism ALERT (NCT04861740)
- Testing
- Autism ALERT, Screening Intervention
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Autism Spectrum Disorder, Autism
Feasibility of Mobile Game System for Potential Treatment of Developmental Delays
The investigators will test the feasibility and preliminary efficacy of a Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful…
- Trial name
- NCT04909710
- Testing
- Mobile Game System for Potential Treatment of Developmental Delays
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Haemophilia, Autism Spectrum Disorder
Prevalence of Autistic Spectrum Disorder (ASD) in Children With Haemophilia
Parents of children with haemophilia will be invited to complete 3 questionnaires to look for traits present in ASD. With consent teacher will complete a further 2 questionnaires.
- Conditions
- Haemophilia, Autism Spectrum Disorder, Social Communication Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05138224
- Volunteers
- 82 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Autism Spectrum Disorder
A Protocol to Streamline Dental Care in Autistic Children
The investigators aim at creating a dedicated pathway to allow accessibility to dental care for ASD children within a hospital Dentistry Department, in order to diminish the need for general anesthesia.
- Trial name
- DentAutism (NCT05553262)
- Testing
- Behavioral support
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- University of Padova
Autistic Disorder
Oxytocin in Spectrum Autism Disorders
Observe effects of oxytocin on individuals with autism spectrum disorder
- Trial name
- OxytocinASD (NCT03183674)
- Testing
- Oxytocin
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Autism Spectrum Disorder
Improving Social Communication in Individuals With ASD Using AI
The purpose of this study is to identify whether researched and commonly used face-to-face interventions can be effectively implemented through artificial intelligence (AI) using an application on the phone or computer.
- Trial name
- NCT05987774
- Testing
- AI Modules for Improving Social Communication
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- Stanford University
Autism
Developing Treatment, Treatment Validation and Treatment Scope in the Setting of an Autism Clinical Trial
Dr. Sherie Novotny of the Department of Psychiatry at UMDNJ-RWJMS and collaborators are starting a treatment trial to determine whether Docosa Hexanoic Acid(DHA), the major omega-3 fatty acid found in the brain and a component of…
- Trial name
- NCT01260961
- Testing
- Docosahexanoic Acid
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Autism Biomarker Consortium for Clinical Trials
This is a multicenter longitudinal study that aims to identify, develop and validate a set of measures that can be used as stratification biomarkers and/or sensitive and reliable objective measures of social impairment in autism…
- Trial name
- ABC-CT (NCT02996669)
- Where
- United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) Characterization Study
The overarching aim of the study is to characterize children and adults with ASDs, and compare them with age-matched controls in relation to their functioning in family, academic, employment, and social spheres.
- Trial name
- NCT00801554
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Study Comparing the Effects of SPM Techniques, Individually vs. Grouped in Children With ASD
Autism is the most prevalent disorder as it affects attention, awareness, cognitive development, social development, and emotional aspects too.
- Trial name
- NCT06661369
- Testing
- Sensory Perceptual Motor Training on Group, Sensory Perceptual Motor Training on Individual
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)
This multi-center, randomized, double-blind, parallel group, placebo-controlled, proof of concept study will investigate the efficacy and safety of RG7314 in adult participants with ASD.
- Trial name
- NCT01793441
- Testing
- RG7314
- Where
- 56 sites in United States
- Volunteers
- 223 people
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder (ASD), Obstructive Sleep Apnea (OSA)
Portable Sleep Monitors in Children With Autism Spectrum Disorder
The goal of this study is to evaluate the ability of a portable sleep monitor to detect obstructive sleep apnea in children with autism spectrum disorder (ASD). The main study objectives are to: 1.
- Trial name
- PrSM (NCT07367022)
- Testing
- Portable sleep monitor (Nox T3s)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Lena Xiao
Autism
Joint Attention Intervention and Young Children With Autism
The purpose of this study is to investigate the effectiveness of an intervention aimed to increase joint attention in 2-4 year old children with autism. The study will be conducted in mainstream preschools in Norway.
- Trial name
- NCT00378157
- Testing
- Joint attention intervention
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Ullevaal University Hospital
Autism, Children
A Realist Evaluation of Autism ServiCe Delivery (RE-ASCeD)
Diagnostic pathways for children with possible autism. Which work best, for whom, when, and at what cost? Autism is a complex neuro-behaviour condition.
- Conditions
- Autism, Children, Family, Diagnoses, Syndromes, and Conditions
- Trial name
- Re-ASCed (NCT04422483)
- Testing
- Realist evaluation
- Where
- United Kingdom
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Sussex Community NHS Foundation Trust
Autism Spectrum Disorder (ASD)
Sensory-Motor Integration for Sensory Processing and Balance in ASD
This randomized controlled trial evaluates the effectiveness of a 16-week structured sensory-motor integration exercise program compared to conventional therapy (Applied Behavior Analysis and massage therapy) in improving sensory…
- Trial name
- SMIE-ASD (NCT06922422)
- Testing
- Sensory-Motor Integration Exercises, Conventional therapy group
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Assiut University
CTNNB1 Gene Mutation
Genotype-phenotype Correlations in Children and Adults With CTNNB1 Mutation
The aim of this study is to explore and define the correlations between genotype and phenotype in patients with CTNNB1 mutations as well as monitor and survey the natural history of the CTNNB1 syndrome.
- Trial name
- Gen-Phe CTNNB1 (NCT04812119)
- Testing
- The Modified Checklist for Autism in Toddlers, Revised with Follow-Up (M-CHAT-R/F), The Autism Spectrum Quotient-Children's Version (AQ-Child), The Autism-Spectrum Quotient (AQ)-Adolescent Version (AQ-Adolescent)
- Where
- 3 sites in Australia, Slovenia
- Volunteers
- 100 people
- Sponsor
- University Medical Centre Ljubljana
Autism Spectrum Disorder, Neurodevelopmental Disorders
Evaluation of Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach)
Children with disabilities often access rehabilitation services to improve their abilities to participate in everyday activities.
- Conditions
- Autism Spectrum Disorder, Neurodevelopmental Disorders, Cerebral Palsy
- Trial name
- NCT04096430
- Testing
- ENGAGE approach (child-oriented goal-setting)
- Where
- 6 sites in Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
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