Clinical trials: Childhood Autism
7q11.23 Microduplication Syndrome (7DUP), Autism Spectrum Disorder (ASD)
Characterization of the Natural History of Microduplication Syndrome 7q11.23
7q11.23 duplication syndrome (7q duplication syndrome/7DUP) is caused by a microduplication of the 7q11.23 chromosomal region, encompassing 26-28 genes, including the GTF2I gene.
- Conditions
- 7q11.23 Microduplication Syndrome (7DUP), Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders (NDD)
- Trial name
- HINADU7 (NCT07469566)
- Testing
- clinical assessment, Parental questionnaires, Cognitive assessment
- Where
- 2 sites in France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Functional Constipation, Emotional Problems
Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation.
A significant group of children with functional constipation (FC) continues to have symptoms despite recommended standard therapy. Underlying psychiatric problems could explain therapy resistance.
- Conditions
- Functional Constipation, Emotional Problems, Behavioural Problems, Developmental Disorder
- Trial name
- NCT03614000
- Testing
- Screening Questionnaires
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Autism, Mental Health Conditions
A Toolkit to Improve Mental Health Treatment for Autistic Individuals
This pilot study is funded by the Organization for Autism Research (OAR). We are conducting a pilot study to improve mental health treatment for autistic individuals.
- Trial name
- NCT07539519
- Testing
- Enhanced Psychotherapy, Treatment as Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Florida International University
Autism Spectrum Disorder (ASD), Neurotypical
Course of Face-to-face Interactions in Adults With Autism
This research explores how adults with autism make eye contact during formal and informal interactions; to what extent the nature of a conversation influences how eye contact is made in terms of length, frequency and overall…
- Trial name
- NCT06925308
- Testing
- Conversation
- Where
- Netherlands
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Schizophrenia, Autism Spectrum Disorder
Biological Implications of the Overlapping Phenomenon Between Childhood Schizophrenia and Autism Spectrum Disorders-Heterogeneity Approach Rather Than Diagnostic Boundary
Complex diseases such as schizophrenia and autism are heterogeneous in clinical presentation and etiology. This high heterogeneity constitutes the challenges for the clinical diagnosis and etiological research, resulting in that…
- Trial name
- NCT06063525
- Testing
- Structural anatomy
- Volunteers
- 230 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
The Listening Program® With Bone Conduction Headphones Changes Hypersensitivity to Sound and Behavioral Responses
There are limited approaches to specifically address auditory sensory over- and under-responsivity (SOR) in children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT05009095
- Testing
- The Listening Program® with bone conduction headphones
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Health
Mental Health Issue, Anxiety Disorders
Arts-based Social Prescribing for Mental Health
This is a parallel-group randomised-controlled trial aiming to assess the effect of exposure to the arts on mental health and wellbeing of community dwelling recipients of mental health care.
- Conditions
- Mental Health Issue, Anxiety Disorders, Affective Disorders, Affective Disorders, Psychotic
- Trial name
- AoP-II (NCT07137572)
- Testing
- Art Prescription
- Where
- Greece
- Volunteers
- 541 people
- Sponsor
- KAVADIA ELENI
Autism Spectrum Disorder, Language Development
HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at…
- Conditions
- Autism Spectrum Disorder, Language Development, Neurocognitive Disorders, Child Language
- Trial name
- EE-TSA-LANG (NCT05586672)
- Testing
- EEG-HR, ADI-R, ADOS-2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Child Development Disorders, Pervasive
Pharmacogenetics of Risperidone in Children With Pervasive Developmental Disorder (PDD)
The purpose of this study is to determine if the known differences in genes influence drug metabolizing enzymes and receptors that are involved in risperidone drug action.
- Trial name
- NCT00166595
- Testing
- Risperidone
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder
Omega-3 Fatty Acids For Treatment Of Young Children With Autism (OMG)
This is a pilot, randomized, placebo-controlled trial of omega-3 fatty acids in autism. Autism, originally described by Kanner in 1943, is among the most severe of neurodevelopmental disorders.
- Trial name
- NCT01248728
- Testing
- Omega-3 Fatty Acids
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Healthy
Oxytocin Effect on Attentional Bias Towards Emotional Expression Faces in Individuals With High and Low Autistic Traits: A Functional Magnetic Resonance Imaging (fMRI) Study
to investigate whether oxytocin alter attentional bias towards emotional expression faces in individuals with high and low autistic traits, and the brain mechanism of this effect
- Trial name
- NCT02741063
- Testing
- screen low autistic subjects, screen high autistic subjects, oxytocin
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorders
Effects of the Anti-inflammatory Flavonoid Luteolin on Behavior in Children With Autism Spectrum Disorders
Background. Increasing evidence indicates that brain inflammation is important in the pathogenesis of neuropsychiatric disorders, including at least a significant proportion of subjects with Autism spectrum disorder (ASD).
- Trial name
- NCT01847521
- Testing
- Luteolin, Quercetin and Rutin combined in a capsule
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Attikon Hospital
Child Development Disorders, Pervasive
Randomized Trial of Parent Training for Young Children With Autism
The purpose of this 24 week study is to determine whether a new Parent Training program is effective in reducing disruptive behaviors in young children with pervasive developmental disorders.
- Trial name
- RUBI (NCT01233414)
- Testing
- Parent Training, Psychoeducational Program
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- Yale University
Autism
Neuropsychopathological Study of Autism
Autism or autism spectrum disorder (ASD) is a relatively common (0.3% in Taiwan), multi-factorial, genetically and clinically heterogeneous, childhood-onset neurodevelopmental disorder.
- Trial name
- NCT01677663
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Irritability Associated With Autism Spectrum Disorder
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to assess KarXT + KarX-EC for the treatment of irritability associated with autism in children and adolescents.
- Trial name
- NCT07285798
- Testing
- KarXT, KarX-EC
- Where
- 67 sites in United States, France and 8 more
- Volunteers
- 176 people
- Sponsor
- Bristol-Myers Squibb
Autism Spectrum Disorder
A Collaborative Public/Private Employment Training and Placement Model ASD Transition Age Youth With Autism Spectrum Disorder (ASD)
The aim of the research project is to conduct evidence-based research on a nationally known vocational rehabilitation (VR) service model (Project Search) for individuals with Autism Spectrum Disorders (ASD).
- Trial name
- ProjSEARCH1 (NCT02360332)
- Testing
- Project SEARCH plus ASD Supports
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Age 3 to 7 Years, Mild Autism Spectrum
the Effect of Formulation on Anxiety in Autist Childre A Randomized Controlled Trial Assesses Spirulina Syrup Plus Risperidone in Children With Non-idiopathic Autism. Anxiety is Measured Using the SCAS (Parent Version) Via Daily Online Surveys for One Week and Throughout a 3-month Follow-up Period.
The aim of this study is to evaluate the effect of a Spirulina syrup formulation on reducing anxiety in children with non-idiopathic autism.
- Conditions
- Age 3 to 7 Years, Mild Autism Spectrum, no Other Illness or Disorder
- Trial name
- Autism Anxiety (NCT07060872)
- Testing
- Spirulina Syrup, Risperidone
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Shahid Sadoughi University of Medical Sciences and Health Services
Autism Spectrum Disorder (ASD)
Navigating the Transition to Adulthood: A Dual Language Mobile App for Latino Youth With ASD and Their Families
The purpose of this study is to determine useability and satisfaction characteristics,product usage data,methodological feasibility parameters and feasibility metrics of the mHealth app adapted intervention on the mental health…
- Trial name
- NCT07170163
- Testing
- ¡Iniciando! mHealth App
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Spectrum Disorder
Exergaming on Hand Dexterity In Autistic Children
Through this study we aim to determine the effect of Exergaming on bimanual hand dexterity in Autistic children. This randomized controlled trial will recruit a sample of 20 autistic children as per the inclusion and exclusion…
- Trial name
- NCT05475132
- Testing
- Exergaming, Conventional Dexterity Exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation
Repetitive behaviors (RBs) are a prevalent feature of Autism Spectrum Disorder (ASD). There are two groups of RBs: lower-order (e.g. motor stereotypies) and higher-order RBs (e.g.
- Trial name
- NCT06645587
- Testing
- Active HD-tDCS over pre-SMA, Active HD-tDCS over left DLPFC
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
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