Clinical trials: Childhood Autism
Autism Spectrum Disorder
A Study of Bumetanide for the Treatment of Autism Spectrum Disorders
The investigators are going to carry out a randomized double-blind placebo-controlled trial to study the efficiency and mechanism of bumetanide on the treatment of children with Autism Spectrum Disorder.
- Trial name
- NCT03156153
- Testing
- Bumetanide
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder
A Study to Investigate the Efficacy, Safety, and Tolerability of JNJ-42165279 in Adolescent and Adult Participants With Autism Spectrum Disorder
The purpose of this study is to evaluate the efficacy of JNJ-42165279 compared with placebo in the improvement of symptoms of Autism Spectrum Disorder (ASD) during 12 weeks of treatment using the Autism Behavior Inventory (ABI).
- Trial name
- Envision (NCT03664232)
- Testing
- JNJ-42165279
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Janssen Research & Development, LLC
Autism Spectrum Disorder, Early Intervention
Biomarkers Trajectories of Early Intervention in Siblings of Children with Autism Spectrum Disorder
This project deals with essential challenges in the context of Autism Spectrum Disorder benefiting from a prospective design in childhood, early intervention and a cutting-edge experimental techniques.
- Trial name
- NCT05614206
- Testing
- Behavioral intervention based on Applied Behavior Analysis principles
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
Improving the Part C Early Intervention Service Delivery System for Children With ASD
Despite strong consensus that early, specialized intervention for children with autism spectrum disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05114538
- Testing
- Reciprocal Imitation Training
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Rush University Medical Center
Autism Spectrum Disorder
Probiotics for Autism Spectrum Disorders: a Randomized Controlled Trial (The PASD Study)
Autism spectrum disorders (ASD) are a group of severe neurodevelopmental conditions characterized by impaired communication and social interaction, as well as repetitive/stereotyped behaviors deriving from a combination of…
- Trial name
- PASD (NCT07345585)
- Testing
- Lactobacillus rhamnosus GG
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Autism Spectrum Disorder, Transition
Evaluating the Efficacy and Effectiveness of SCOPE - RCT
The study will entail an evaluation of the feasibility, acceptability, efficacy and effectiveness of SCOPE coach supported internet-delivered psychoeducative program using a randomized controlled design in a clinical health care…
- Trial name
- SCOPERCT (NCT03665363)
- Testing
- SCOPE, Self-study
- Where
- Sweden
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Autism Spectrum Disorder
pBFS-guided Noninvasive Neuromodulation for Pre-school Children With ASD
This randomized controlled trial aims to evaluate the efficacy and safeness of the pBFS-guided rTMS intervention for core symptom relief in pre-school children with autism spectrum disorder (ASD).
- Trial name
- NCT06031948
- Testing
- active iTBS
- Volunteers
- 50 people
- Sponsor
- Changping Laboratory
Psychiatric or Mood Diseases or Conditions, Neuropsychiatric Syndrome
Effect and Cost-effectiveness of the Everyday Life Rehabilitation Intervention
The person-centered, motivational, recovery-, and activity-based intervention model 'Everyday Life Rehabilitation´ (ELR), integrated in sheltered and supported housing facilities for people with severe psychiatric disabilities…
- Conditions
- Psychiatric or Mood Diseases or Conditions, Neuropsychiatric Syndrome, Psychosis, Autism
- Trial name
- ELR (NCT05056415)
- Testing
- Everyday Life Rehabilitation (ELR), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Umeå University
Autism
Valproate Response in Aggressive Autistic Adolescents
This study will examine the effect of valproate, a medication used to treat seizures and bipolar disorder, on aggressive behavior in children and adolescents with autism.
- Trial name
- NCT00065884
- Testing
- Valproate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Keep Achieving:The Impact of Group Based Activity Programmes on Children Who Have Autism and Their Families
Participation in structured activities and physical activity (PA) have been linked to several indicators of positive development such as self-esteem and psychological health as well as greater academic outcomes and lower school…
- Trial name
- NCT04165655
- Testing
- Keep Achieving (KA)
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Midlands Psychology CIC
Autism
Evaluating Pathways Mutual Gaze Protocol on Social Skills in Young Children Suspected of Autism
Purpose of the Study: The goal of this clinical trial is to find out if a technique called the "mutual gaze procedure," used in Pathways Early Intervention (Pathways), is the key to helping improve social communication, language…
- Trial name
- NCT06596226
- Testing
- Pathways Parent Mediated Intervention, Pathways Parent Mediated Intervention without Mutual Gaze
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder
Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills
The investigators currently provide the NEAR method (neuropsychological educational approach to cognitive remediation) for people with neurocognitive difficulties, without distinguishing between ASD and schizophrenia.
- Trial name
- NEAR-TSA (NCT05786898)
- Testing
- NEAR-TSA
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier St Anne
Autism Spectrum Disorder
A Study Looking at How Well Children With Autism Spectrum Disorder on Medications Like Having More Protein
Antipsychotic medications are commonly prescribed in children and adults with ASD (Curtin, Jojic \& Bandini, 2014). But weight gain has been known to be one of the less desirable effects of these medications, increasing one's…
- Trial name
- NCT03708614
- Testing
- Controlled energy diet with elevated protein intake
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Autism Research Project With Non-Invasive Near-Infrared Light Stimulation
The investigators have previously shown that the administration of low-level infrared light is a safe and non-invasive procedure which improves cognition and emotion, as well as enhances brain metabolic activity.
- Trial name
- NCT06203938
- Testing
- Transcranial infrared light stimulation
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Francisco Gonzalez-Lima, PhD
Food Selectivity
Healthy Eating ASD
Most studies which have addressed food selectivity among children with autism spectrum disorders have been conducted in either clinic or home settings.
- Trial name
- NCT04075552
- Testing
- Pre Meal Presentation, Pre Meal Presentation + Modeling, Pre Meal Presentation + Token Economy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Penn State University
Autistic Disorder, Autism
Randomized Controlled Trial of Acupuncture Versus Sham Acupuncture in Autistic Spectrum Disorder
We aim to study the efficacy of Acupuncture versus sham acupuncture in children with ASD.
- Trial name
- NCT00352248
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
ASD
Effect and Mechanism of Social Interaction Treatment on ASD Children
Current study try to find out whether social interaction treatment is effective for ASD children. ASD children will be divided into three groups, social interaction treatment group, neuronal cognition treatment and routine…
- Trial name
- NCT04327648
- Testing
- Social interaction treatment, Neuronal cognition treatment, Routine treatment
- Volunteers
- 90 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Autism Spectrum Disorder
Validation of the French Adaptation of the RAADS-R Scale : Scale of Asperger Syndrome Diagnosis
The diagnosis of developmental disorders in adults is still difficult. Indeed, in France, there is not questionnaires to easily and accurately diagnose this disorder. Several diagnostic scales were developed in English.
- Trial name
- RAADS-R (NCT02826148)
- Testing
- RAADS-R scale
- Volunteers
- 324 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Enhancement of Behavioral and Cognitive Outcomes in Autism Spectrum Disorder Via Neurostimulation
Autism spectrum disorder (ASD) encompasses a range of limitations in reciprocal social and communicative milestones, as well as restrictive and/or repetitive patterns of behavior which lead to significant functional challenges…
- Trial name
- NCT05371912
- Testing
- Trans Cranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Christiana Care Health Services
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