Clinical trials: Childhood Cancer Survivors
Survivors of Childhood Cancer, Acute Lymphoblastic Leukemia, Childhood
Feasibility and Acceptability of Remote Saliva Collection
The purpose of this study is to evaluate the practicality and acceptability of collecting biological samples and health information from childhood survivors of acute lymphoblastic leukemia (ALL) and their siblings.
- Trial name
- NCT07884474
- Testing
- Salivary Cortisol Collection, Blood Biomarker Collection, Hair Cortisol Collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Pediatric Cancer
LIFE Cancer Survivorship Database for Pediatric Cancer
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes.
- Trial name
- NCT01518400
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Children's Hospital Los Angeles
Pediatric Cancer
ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Survivors of Childhood Cancer
Development and Usability Testing of the ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Children, Adolescent and Young Adults (AYA) survivors of childhood cancer
- Trial name
- NCT05792566
- Testing
- Atomic app
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Connecticut Children's Medical Center
Childhood Cancer, Survivorship
Aftercare of Childhood Cancer Survivors in Switzerland
The Aftercare of Childhood Cancer Survivors in Switzerland (ACCS) study is a multicenter cohort study designed to investigate transition of follow-up care from pediatric oncology to adult care in a prospective and longitudinal…
- Conditions
- Childhood Cancer, Survivorship, Transition
- Trial name
- ACCS (NCT04284189)
- Testing
- Transition model
- Where
- 3 sites in Switzerland
- Volunteers
- 140 people
- Sponsor
- Kantonsspital Aarau
Smoking, Cancer
Parent Willingness to Participate in Tobacco Trials in the Pediatric Clinical Setting
Little is known about what factors influence parental decisions to participate or to decline participation in tobacco trials offered in the pediatric clinical setting.
- Conditions
- Smoking, Cancer, Sickle Cell Disease
- Trial name
- NCT01673243
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
Cognitive Intervention at the End of Therapy for Survivors of Childhood ALL Treated on TOTXVI
Computer-based cognitive training has been found to be helpful for improving attention and working memory in pediatric and adult patients with existing cognitive difficulties. A previous study was conducted at St.
- Trial name
- NCT03187977
- Testing
- Cognitive training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Jude Children's Research Hospital
PreDiabetes, Adult Children
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
This is a first-in survivor, single-arm pilot study with the goal of establishing evidence of feasibility and safety of a combined pharmacologic (metformin) and lifestyle intervention (using an existing digital platform) to…
- Trial name
- NCT04742751
- Testing
- Metformin, Digital Intervention
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- St. Jude Children's Research Hospital
Cancer Survivors
Virtual Exercise Training and Its Impact on Bone Compartments in Adult Survivors of Childhood Cancer
Childhood cancer is a rare disease but a significant cause of death in children and adolescents. The incidence of childhood cancer is 1case per 300 cases of adult cancer, but surviving to it has important sequels.
- Trial name
- 3D-BONE (NCT07022262)
- Testing
- Progressive resistance training plus impact loading
- Where
- Spain
- Volunteers
- 116 people
- Sponsor
- Universidad de Granada
Cancer, Glioma
Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
Advances in medical care have significantly improved survival among children with cancer. In China, the 5-year survival rate has reached 71.9%.
- Conditions
- Cancer, Glioma, Leukemia (Both ALL and AML)
- Trial name
- SC-Het-GM-CCS (NCT07450872)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Childhood Cancer
Inattention in Childhood Cancer Survivors
Specific Aim 1: To assess the feasibility and acceptability of a home-based, computerized cognitive training program with survivors of central nervous system-impacting pediatric cancer (e.g.
- Trial name
- TRICCS (NCT00636337)
- Testing
- Attention Training
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Duke University
Childhood Cancer Survivors, Fertility
Fertility and Ovarian Reserve in Female Childhood Cancer Survivors
Ovarian function impairment affects the quality of life of the survivors of paediatric cancer by impacting fertility, bone quality and mental and cognitive health.
- Conditions
- Childhood Cancer Survivors, Fertility, Ovarian Reserve, CED
- Trial name
- PRINCESS (NCT06626282)
- Where
- 3 sites in Belgium
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Cardiovascular Risk, Pediatric Cancer
Vascular Assessment in Adult Survivors of Childhood Cancer
This is an observational study that will collect data from adult survivors of childhood cancer and compare it to data collected from age- and gender-matched controls for the purpose of assessing vascular risk among cancer…
- Trial name
- NCT02010190
- Where
- United States
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia
Motor Proficiency And Physical Activity in Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
The primary goal of this study is to provide comprehensive and objective information on impairments of musculoskeletal health, sensory function, and fitness among a large group of childhood ALL survivors, and to define high risk…
- Trial name
- NCT01047020
- Where
- United States
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Childhood Cancer Survivors
A Study of Time-Restricted Eating in Childhood Cancer Survivors
This study will look at whether motivational sessions (including regular calls with a trained health coach) in combination with time-restricted eating (TRE) is an effective way to achieve weight loss and lower cardiometabolic…
- Trial name
- NCT07009288
- Testing
- Children's Oncology Group Heart Health Link, Monthly weights, Fasting
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Generalized Anxiety, Introspective & Anxiety-Prone Patient
Validation of a Rapid Screening Tool for Anxiety-depressive Disorders in Children, Adolescents and Young Adults Treated in Oncology. Multicenter Study.
In France today, it is estimated that one in every 850 people aged between 20 and 45 is a childhood cancer survivor (CCS), equivalent to around 40,000 to 50,000 people.
- Conditions
- Generalized Anxiety, Introspective & Anxiety-Prone Patient, Depression, Anxiety, Survivors of Childhood Cancer
- Trial name
- HARMONY-Tool (NCT07117058)
- Testing
- New rapid screening tool for anxiety and depressive disorders, SCARED-R-51 (Screen for Child Anxiety Related Emotional Disorders-Revised), HADS (Hospital Anxiety and Depression Scale)
- Where
- 7 sites in France
- Volunteers
- 545 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
ALL, Hodgkin Lymphoma
Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer
Survivors of childhood cancer are at greater risk for long-term cognitive impairments that include attention, executive function, intelligence, memory, and processing speed.
- Conditions
- ALL, Hodgkin Lymphoma, Cancer, Survivorship
- Trial name
- NCT05550948
- Testing
- Transcranial photobiomodulation (tPBM) - Mobile System
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- St. Jude Children's Research Hospital
Pediatric Cancer
Barriers and Facilitators in Access to OT/PT in Pediatric Cancer Survivors
This study aims to identify the modifiable facilitators and barriers to occupational and physical therapy care for children during and after cancer treatment that may be contributing to disparities in health outcomes.
- Trial name
- NCT05305950
- Testing
- Patient population
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Childhood Cancer, Muscle Weakness
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
The participants are being asked to take part in this trial, because the participant is a survivor of childhood cancer or agreed to be part of a volunteer group to understand the relation between cancer and cancer treatment and…
- Trial name
- NCT06819475
- Testing
- Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, Physical function assessment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Brain Neoplasms, Endocrine System Diseases
Assessment of Endocrine and Metabolic Late Effects After Childhood Brain Tumor Treatment
This prospective, single-group interventional study evaluates endocrine and metabolic late effects in survivors of primary brain tumors treated during childhood.
- Conditions
- Brain Neoplasms, Endocrine System Diseases, Metabolic Diseases
- Trial name
- NCT07716579
- Testing
- Study-Specific Endocrine and Metabolic Late-Effects Assessment
- Where
- Slovenia
- Volunteers
- 12 people
- Sponsor
- Institute of Oncology Ljubljana
Acute Leukemia, Acute Lymphoblastic Leukemia
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors
This clinical trial evaluates a high intensity electronic health (eHealth) intervention program for reducing learning disparities in children with cancer.
- Conditions
- Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Lymphoblastic Lymphoma
- Trial name
- NCT05428176
- Testing
- Best Practice, Internet-Based Intervention, Quality-of-Life Assessment
- Where
- 4 sites in United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center