Clinical trials: Childhood Pneumonia
Pneumonia Childhood, Lower Respiratory Tract Infection
The Norwegian Antibiotics for Pneumonia in Children Study
This study evaluates the effect of amoxicillin in the treatment of lower airway infections in preschool children. Half of the patients will receive amoxicillin, while the other half will receive placebo.
- Trial name
- NAPiC (NCT03446534)
- Testing
- Amoxicillin
- Where
- 9 sites in Norway
- Volunteers
- 884 people
- Sponsor
- Oslo University Hospital
Malaria, Dengue
Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal
This trial aims to validate a novel clinical care strategy based on a electronic clinical decision support algorithm (CDSA) combined with point of care rapid diagnostic tests by evaluating its impact on antibiotic prescription…
- Conditions
- Malaria, Dengue, Influenza -Like Illness, Diarrhea
- Trial name
- NCT05050825
- Testing
- Patient clinical management based on the CDSA strategy
- Where
- 4 sites in Senegal
- Volunteers
- 470 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Cancer
Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation
RATIONALE: Antivirals such as ribavirin are used to treat infections caused by viruses. It is not yet known if ribavirin is more effective with or without monoclonal antibody therapy in treating patients who develop RSV pneumonia…
- Trial name
- NCT00014391
- Testing
- palivizumab, ribavirin
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Childhood Severe Illness, Pneumonia
Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in Kenya and Senegal
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Childhood Severe Illness, Pneumonia, Primary Health Care, Hypoxia
- Trial name
- TIMCI (NCT05065320)
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 51,590 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Childhood Anxiety Disorder, Childhood Depression
Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Investigators developed a brief standardized internet-delivered cognitive-behavioral program for treating anxious and depressive symptoms in children and adolescents in the context of COVID-19 pandemics in Brazil.
- Trial name
- NCT05139433
- Testing
- Telepsychotherapy, Psychoeducational Videos
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- University of Sao Paulo
Pneumonia Childhood, Intensive Care Unit
Effect Of Cough Assist Device On Hemodynamic Status And Oxygen Saturation For Ventilated Children
Statement of the problem: •Is there an effect of the cough assist device on Hemodynamic status and oxygen saturation for ventilated children? Null hypothesis There will be no effect of cough assist device on hemodynamic status…
- Conditions
- Pneumonia Childhood, Intensive Care Unit, Children
- Trial name
- NCT06154876
- Testing
- Cough assist device
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Pneumonia Childhood
Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
Lung ultrasound (LUS) in combination with a biomarker has not yet been studied. The investigators propose a clinical trial where the primary aims are: 1.
- Trial name
- PROLUSP (NCT04217980)
- Testing
- Lung ultrasonography (LUS) or Chest X ray (CXR)
- Where
- 2 sites in Spain
- Volunteers
- 202 people
- Sponsor
- Fundació Sant Joan de Déu
Anxiety Disorder of Childhood or Adolescence
Mental Health Support for SickKids Children and Families During COVID-19 Using Established eHealth Interventions
Coronavirus disease 2019 (COVID-19) and associated emergency measures (EM) have dramatically impacted the lives of children/adolescents (children) and families.
- Trial name
- NCT04408027
- Testing
- Virtual-Care Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- The Hospital for Sick Children
Pneumonia, Laboratory Confirmed Influenza
Flu Vaccine Against Childhood Pneumonia, Bangladesh
Pneumonia is the leading cause of child death worldwide. Data from Bangladesh indicates that influenza has a substantial association with pneumonia among children less than two years old.
- Trial name
- NCT01319955
- Testing
- Trivalent inactivated influenza vaccine
- Where
- Bangladesh
- Volunteers
- 3,508 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pneumonia, Childhood Pneumonia
mHealth for Pneumonia Prevention
In Pakistan, pneumonia and recurrent wheeze in children under five pose significant threats to children's health. Despite being preventable, more than 90,000 children die each year due to pneumonia in Pakistan, making it one of…
- Conditions
- Pneumonia, Childhood Pneumonia, Infectious Disease, Acute Respiratory Infection
- Trial name
- NCT04493047
- Testing
- Mobile health (mHealth) for pneumonia
- Where
- Pakistan
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Diarrhea, Pneumonia
64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings
The purpose of this study is to compare the occurrence of childhood diarrheal disease and pneumonia in subjects under the age of 5 years in low resource settings who have received prophylactic 64N nutraceutical (64N)as a neonate…
- Trial name
- NCT02231047
- Testing
- 64N Nutraceutical, No 64N Nutraceutical
- Where
- Guatemala
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- H2O Health and Agriculture LLC
Childhood Pneumonia, Hypoxemia
Assessing the Feasibility and Effectiveness of Introducing Pulse Oximetry in IMCI Services
The purpose of the study is to assess the feasibility, acceptability and operational challenges of introducing Pulse Oximeter (PO) in IMCI services to manage acute respiratory infections at first-level primary care facilities in…
- Trial name
- NCT03750747
- Testing
- Pulse Oximeter
- Where
- Bangladesh
- Volunteers
- 612 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Pneumonia Childhood
Acute Respiratory Infection Diagnostic Aids (ARIDA) Controlled Accuracy Evaluation Protocol
Pneumonia is the leading infectious cause of death among children under 5 years of age globally. Many pneumonia deaths result from late care seeking and inappropriate treatment due to misdiagnosis of symptoms.
- Trial name
- NCT03067558
- Testing
- Children's automated respiratory rate monitor, MK2 Acute Respiratory Infection (ARI) Timer
- Where
- Ethiopia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Malaria Consortium
Pneumonia Childhood
The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia
The goal of this study is to compare the mean length of hospital stay between children with pneumonia receiving melatonin as an adjuvant therapy and those receiving standard of care alone.
- Trial name
- NCT06949904
- Testing
- Melatonin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mian Muhammad Hassan Ahmed
Pneumonia Childhood
Thoracic KT on Pulmonary Function Ichildren with Pneumonia
This study aimed to investigate the effect of thoracic kinesio-tape on Pulmonary Functions, time to clinical resolution and respiratory rate and arterial oxygen saturation in children with pneumonia.
- Trial name
- NCT06573047
- Testing
- kinesotape, Chest physiotherapy exercises
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pneumonia Childhood, Vitamin C
Effect of Vitamin C on Length of Hospital Stay in Children With Severe Pneumonia
Severe pneumonia is a common and serious illness in young children and often requires hospital admission. This clinical trial aims to find out whether adding vitamin C to standard treatment can reduce the length of hospital stay…
- Conditions
- Pneumonia Childhood, Vitamin C, Hospital Stay Time
- Trial name
- NCT07414693
- Testing
- Antibiotics administration, Vitamin C
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Pneumonia
CHIZAP: Community- and Health Facility-Based Intervention With Zinc as Adjuvant Therapy for Childhood Pneumonia
The aim of the study described is to measure the degree with which zinc given as adjunct therapy to standard antibiotic treatment during childhood pneumonia reduces the risk of treatment failure and the duration of the illness.
- Trial name
- NCT00148733
- Testing
- Zinc
- Where
- Nepal
- Volunteers
- 2,628 people
- Sponsor
- Centre For International Health
Diarrhea, Infantile, Childhood Pneumonia
Bihar Evaluation of Social Franchising and Telemedicine
This study will conduct an evaluation of the World Health Partners (WHP) private provider project to see if the social franchising and telemedicine project has an impact on health outcomes in treatment vs. control areas.
- Trial name
- BEST (NCT01345695)
- Where
- India
- Volunteers
- 106,380 people
- Sponsor
- Duke University
Covid-19, Obesity, Childhood
COVID-19, Obesity and Lifestyle in Children
This study aims to evaluate the impact of the COVID-19 pandemic and its measures on lifestyle in Dutch children between 4 - 18 years.
- Conditions
- Covid-19, Obesity, Childhood, Lifestyle, Lifestyle, Healthy
- Trial name
- COLC (NCT04411511)
- Testing
- Exposure to the Dutch measures due to the Covid-19 pandemic.
- Where
- Netherlands
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pneumonia Childhood
Improving CarE for Community Acquired Pneumonia 1
Children with pneumonia presenting to the emergency department at Monroe Carell Jr. Children's Hospital at Vanderbilt or Children's Hospital of Pittsburgh will be potentially eligible for study.
- Trial name
- ICE-CAP1 (NCT03760419)
- Testing
- Clinical Decision Support
- Where
- United States
- Volunteers
- 1,027 people
- Sponsor
- Vanderbilt University Medical Center