Clinical trials: Childhood Vaccination
Tuberculosis
Should Low Birth Weight Infants Be Vaccinated With BCG Vaccine at Birth in Developing Countries?
The World Health Organization (WHO) currently recommends BCG vaccination at birth in developing countries. Pre-term infants should be vaccinated when they reach the chronological age of 40 weeks.
- Trial name
- NCT00146302
- Testing
- Bacille Calmette Guerin (BCG)
- Where
- Guinea-Bissau
- Volunteers
- 2,320 people
- Sponsor
- Bandim Health Project
Leukemia
Vaccine Therapy in Treating Patients With Acute Lymphoblastic Leukemia
The prognosis for children and adults with acute lymphoblastic leukemia (ALL) has improved significantly over the years. Nevertheless, patients who experience disease relapse or induction failure along with patients having…
- Trial name
- NCT00020670
- Testing
- CD 40
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Dana-Farber Cancer Institute
Vaccine Refusal, Pregnancy Related
The Motivational Interview Teqhnique in Pregnant Women Who Are Hesitant in Childhood Vaccines
Vaccine hesitancy is defined by World Health Organization(WHO) "Vaccine Hesitancy Working Group" as a delay in acceptance or refusal of vaccines despite availability of vaccination services(MacDonald,2015).
- Conditions
- Vaccine Refusal, Pregnancy Related, Motivation
- Trial name
- NCT05648513
- Testing
- Motivational Interwiev
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Immunization; Infection
Evaluation of Conditional Cash Transfers (CCTs) for Immunization
Like many developing countries, Pakistan faces a public health challenge of low and incomplete immunization rates of children, only 54% of children aged 12 to 24 months are fully immunized, which leaves children susceptible to…
- Trial name
- NCT03355989
- Testing
- Conditional Cash Transfer, SMS Reminder
- Where
- Pakistan
- Volunteers
- 11,197 people, healthy volunteers welcome
- Sponsor
- Interactive Research and Development
Evaluating Impact of PACV on Vaccine Hesitancy Among Parents of Newborns
Impact of PACV Administration on Vaccine Hesitancy
Our objective is to assess the impact of administering the PACV to parents of newborns. We also sought to assess the prevalence of vaccine hesitancy among parents of newborns in Houston, TX and to characterize the demographics of…
- Trial name
- NCT04450940
- Testing
- PACV survey
- Volunteers
- 1,705 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Fever, Adverse Event Following Immunisation
Safety of RSV Preventive Monoclonal Antibody
This is a prospective, randomized, open-label clinical trial to evaluate the safety of administration of respiratory syncytial virus (RSV) preventive monoclonal antibody and other routine childhood vaccines given simultaneously…
- Trial name
- NCT07158814
- Testing
- Respiratory Syncytial Virus (RSV) Preventive Monoclonal Antibody
- Where
- 6 sites in United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- Duke University
Human Papillomavirus
Human Papillomavirus (HPV) Vaccination Among Survivors of Childhood Cancer
This study will focus on the primary objectives: To estimate the prevalence of HPV vaccination among a large cohort of childhood cancer survivors and an acquaintance control group.
- Trial name
- NCT01117389
- Where
- United States
- Volunteers
- 587 people
- Sponsor
- St. Jude Children's Research Hospital
Mortality, Morbidity
Vitamin A Supplementation With Routine Childhood Vaccines and Mortality and Morbidity
Vitamin A supplementation (VAS) is important for the immune system and may interact with different childhood vaccinations. We have hypothesized that the improved survival after VAS may depend on vitamin A amplifying the…
- Trial name
- NCT00168623
- Testing
- Vitamin A
- Where
- Guinea-Bissau
- Volunteers
- 6,200 people
- Sponsor
- Bandim Health Project
Immunization Coverage, Breastfeeding
Testing Content Delivery Models for MomConnect
The case for mobile health (mHealth) has been gaining traction as a source to improve health outcomes of individuals. mHealth refers to the use of Information and Communication Technologies (ICT) to support health care.
- Conditions
- Immunization Coverage, Breastfeeding, Hematological Diseases
- Trial name
- MQR (NCT05505760)
- Testing
- Quality-Based Digital Messaging
- Where
- South Africa
- Volunteers
- 8,867 people
- Sponsor
- IDinsight
Childhood Vaccination
Age-Specific Strategies for Immunization Reminders and Recalls
The objective of this study was to assess the relative effectiveness of reminder/recall strategies among children who live in an urban area targeting alternative age-specific milestones.
- Trial name
- NCT01770496
- Testing
- Childhood vaccination reminder / recall notification
- Where
- United States
- Volunteers
- 10,175 people
- Sponsor
- University of Michigan
Childhood Vaccination
Vaccine Hesitancy Intervention--Provider (VHIP)
The primary aim of this trial is to test the effectiveness of an intervention to train primary care physicians to determine if it leads to decreased parental vaccine hesitancy.
- Trial name
- VHIP (NCT01667354)
- Testing
- Academic Detailing
- Where
- United States
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Childhood Vaccinations
Tailoring of Vaccine-Focused Messages: Moral Foundations
This study is the first phase of a trial examining decision making about vaccines. This phase tests the impact of targeted vaccine-focused health messages on vaccine beliefs held by parents of young children and pre-adolescents.
- Trial name
- NCT02851459
- Testing
- Baseline Survey, Pre-intervention Survey, Morally Congruent Message
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Emory University
Diphtheria, Tetanus
Randomized Controlled Trial of the Impact of Mobile Phone Delivered Reminders and Travel Subsidies to Improve Childhood Immunization Coverage Rates and Timeliness in Western Kenya
The project goal is to conduct a randomized controlled trial (RCT) to test whether mobile phone short message system (SMS) reminders, either with or without mobile-phone based travel subsidies will improve timeliness, coverage…
- Conditions
- Diphtheria, Tetanus, Pertussis, Hepatitis B
- Trial name
- m-SIMU (NCT01878435)
- Testing
- SMS reminder, Travel subsidy, Travel subsidy 2
- Where
- Kenya
- Volunteers
- 2,018 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Influenza, Human
Childhood Influenza Immunisation Invitation Trial in Schools
This study will investigate whether influenza vaccine uptake by school-age children (in school-based clinics) can be increased by making behavioural-insight informed changes to the invitation process which encourage parents to…
- Trial name
- NCT02883972
- Testing
- Intervention letter, Control letter, Reminder
- Volunteers
- healthy volunteers welcome
- Sponsor
- Public Health England
Vaccination, Hematologic Malignancy
Vaccination for Children of H&O and Their Parents
The purpose of this study is to study on compliance, safety and effectivity of vaccination for children with hematologic malignancies or solid tumors and their parents.
- Conditions
- Vaccination, Hematologic Malignancy, Solid Tumor, Childhood
- Trial name
- NCT03373656
- Testing
- Vaccination, No Vaccination
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Children's Cancer Group, China
Diphtheria, Pertussis
Study to Assess if Quinvaxem Can be Interchanged With Other Pentavalent Vaccines During Standard Childhood Vaccination
This is a study to show that vaccination with 1 dose of Tritanrix HB+Hib followed by Quinvaxem vaccine as the 2nd and 3rd dose is not inferior to vaccination with Quinvaxem for all 3 doses, with respect to protection against all…
- Conditions
- Diphtheria, Pertussis, Tetanus, Hepatitis B
- Trial name
- NCT01357720
- Testing
- Quinvaxem, Quinvaxem/Tritanrix
- Where
- Philippines
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Crucell Holland BV
Childhood Influenza Vaccination, School-located Influenza Vaccination
Efficacy Study of School-located Influenza Vaccination Clinics to Increase Influenza Vaccination Rates in Monroe County, New York
Children in schools in which influenza vaccination clinics are held during school hours will have higher rates of influenza vaccination than children in control schools (no school-located clinics offered)
- Trial name
- SKIPP RCT (NCT02227186)
- Testing
- School-located Influenza Vaccination Clinic
- Where
- United States
- Volunteers
- 20,461 people
- Sponsor
- University of California, Los Angeles
Influenza
From Innovation to Solutions: Childhood Influenza Vaccination Planning
The purpose of this study is to increase childhood influenza vaccination rates using the FDA licensed influenza vaccines according to national guidelines in a randomized cluster trial in which primary care offices are randomized…
- Trial name
- NCT01664793
- Testing
- 4 Pillars Immunization Toolkit
- Where
- United States
- Volunteers
- 87,665 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Poliomyelitis
Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules
This is a phase IV open-label randomized clinical trial that will compare intestinal and humoral immunity in infants receiving inactivated poliovirus vaccine (IPV) and two or three doses of bivalent oral poliovirus vaccine (bOPV).
- Trial name
- NCT02412514
- Testing
- bOPV (three dose), bOPV (two dose), IPV
- Where
- Bangladesh
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV
Measuring the Impact of Integrating Maternal and Newborn HIV Testing With Childhood Immunization Services
This randomized evaluation measured the impact of two levels of support for the integration of infant and postpartum maternal HIV testing with routine immunization services in Southern Zambia on the number of postpartum maternal…
- Trial name
- NCT02479659
- Testing
- HIV testing commodity reinforcement, Policy reinforcement meeting, Opt-out HIV testing for mothers and newborns
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IDinsight