Clinical trials: Children, Adolescents
Autism Spectrum Disorder
The Effectiveness of OT-ParentShip on Parental Resilience and Functioning of Adolescents With High Functioning Autism
The goal of this clinical trial is to evaluate the efficacy of the OT (Occupational Therapy)-ParentShip intervention program for parents of adolescents with Autism. A mixed method, two group, randomized controlled trial (RCT).
- Trial name
- NCT05879705
- Testing
- Parent intervention
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
HIV-1 Infection, H1N1
Laboratory Study of Licensed H1N1 Influenza Vaccines in HIV-1 Perinatally Infected Children and Youth
The purpose of this research study is to evaluate the immune response to the H1N1 influenza or "flu" vaccine. The "immune response" is how your body recognizes and defends itself against bacteria, viruses, and substances that may…
- Conditions
- HIV-1 Infection, H1N1, Influenza, Flu
- Trial name
- NCT01484522
- Testing
- FluMist, Fluvirin, Fluzone
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 149 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Sleep Bruxism, Adolescent
Effectiveness of Melissa Officinalis for the Treatment of Probable Sleep Bruxism in Children and Adolescents
Objective: To investigate, through a controlled and randomized clinical trial, the effectiveness of using Melissa officinalis in different concentrations in the treatment of children and adolescents with probable sleep bruxism.
- Conditions
- Sleep Bruxism, Adolescent, Children, Temporomandibular Joint Disorders
- Trial name
- NCT06214637
- Testing
- Melissa
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Adolescent Idiopathic Scoliosis
Effect of VRGs on Changing the Center of Gravity Location in AIS
The purpose of this clinical trial is to examine the effect of virtual reality games (VRG) on changing the location of the center of gravity in children with adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT05901792
- Testing
- Virtual Reality Games, Waiting List
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istanbul University - Cerrahpasa
Differentiated Thyroid Cancer, Pediatric Cancer
Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)
Papillary thyroid cancer (PTC) is the most common form of differentiated thyroid cancer (DTC). The traditional first line treatment for patients with advanced DTC after surgical resection is radioactive iodine (RAI) therapy.
- Conditions
- Differentiated Thyroid Cancer, Pediatric Cancer, Cancer, Cancer, Thyroid
- Trial name
- RAISE (NCT06458036)
- Testing
- Selpercatinib Monotherapy, 131I Therapy
- Where
- 5 sites in United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital of Philadelphia
Physical Activity, Social Responsibility
Imitation-based Dog Assisted Intervention, for Children With Developmental Disabilities.
This R21 application will provide a multidisciplinary One Health approach to DAID physical activity intervention for adolescents with developmental disabilities and their family dog.
- Trial name
- NCT03462407
- Testing
- DAID, Dog walking
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Pediatric Cancer, Psychology, Child
Usability and Utility of Mindfulness-based Life Management Social Robots for Children and Adolescents in the Long-term Treatment
The purpose of this study is to apply social robot-based mindfulness-based life management content to pediatric and adolescent patients in the long-term disease treatment process and to assess usability and effectiveness of the…
- Trial name
- NCT06763042
- Testing
- Mindfulness-based Life Management Social Robots
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Adolescent Behavior
Sagittal Alignment and Extensibility With Pilates in Adolescents
Several research show a high prevalence of spinal misalignments and a lack of stability of the spine in the adolescent population.
- Trial name
- SagittalAlig (NCT03962842)
- Testing
- Pilates method
- Where
- Spain
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Diphtheria, Tetanus
Sanofi Pasteur's Tdap Combined Vaccine as a Booster Versus Local DT Vaccine in Children or Versus Local Td Vaccine in Adolescents and Adults in China.
The aim of the study is to assess the immunogenicity and safety profile of ADACEL compared to local adsorbed diphtheria and tetanus combined vaccine (local DT or local Td vaccine in participants in China.
- Conditions
- Diphtheria, Tetanus, Pertussis
- Trial name
- NCT01993173
- Testing
- Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Tdap (ADACEL), DT vaccine (Diphtheria and Tetanus Combined Vaccine, Adsorbed), Td vaccine (Diphtheria and Tetanus Combined Vaccine for Adults and Adolescents, Adsorbed)
- Where
- China
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Obesity, Child Development
CrescNet - Growth Monitoring Network
CrescNet is a network of primary care physicians and pediatricians (n=219) and endocrinological treatment centers (n=33), established in Leipzig in 1998, whose aim is to improve the early detection of growth disorders.
- Conditions
- Obesity, Child Development, Growth Disorders
- Trial name
- CrescNet (NCT03072537)
- Where
- Germany
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Nocturnal Enuresis
Study With Two Different Doses of Desmopressin Orally Lyophilisate Tablet With Nocturnal Enuresis
This is multi-center, randomized, placebo-controlled, parallel-group, double-blind, dose-escalating clinical trial designed to assess the efficacy and safety of desmopressin orally lyophilisate for the treatment of nocturnal…
- Trial name
- PNE (NCT01078753)
- Testing
- Desmopressin
- Where
- 15 sites in Japan
- Volunteers
- 89 people
- Sponsor
- Ferring Pharmaceuticals
Childhood Cancer
Technology-Based Well-Being Process Program (WEBEPROP) for Children and Adolescents in Palliative Care
Objective: The research was planned to evaluate the effectiveness of the 8-week technology-based Well-Being Process program for children and adolescents in the palliative care period.
- Trial name
- NCT05457153
- Testing
- Well-Being Process Program (WEBEPROP)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Schizophrenia, Schizoaffective Disorder
Efficacy and Tolerability Study of Betahistine to Ameliorate Antipsychotic Associated Weight Gain
The study attempts to evaluate a histamine analog long used for the treatment of Meniere's disease, betahistine, that shows promise in reversing the antihistaminergic effects thought to be involved in antipsychotic induced weight…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar I Disorder
- Trial name
- NCT00709202
- Testing
- Betahistine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Mental Well-being, Physical Well-Being
Mental and Physical Well-being and School Absence Among School Children Using Nicotine Pouches Compared to Their Peers
This cross-sectional study investigates whether the use of nicotine pouches is associated with poorer mental and physical well-being and increased school absence among Danish adolescents.
- Conditions
- Mental Well-being, Physical Well-Being, Adolescent, Nicotine Pouch Self-Administration
- Trial name
- NCT07678853
- Where
- Denmark
- Volunteers
- 10,800 people
- Sponsor
- University of Southern Denmark
Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors
Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic Disorders
Preventive measures are increasingly coming to the forefront of medicine. Many of these measures can be implemented as early as childhood and adolescence.
- Conditions
- Lipid Metabolism Disorders, Lipid Metabolism, Inborn Errors, Congenital Heart Disease, Inflammatory Bowel Disease (IBD)
- Trial name
- FAMELIPIDCHILD (NCT07716488)
- Testing
- blood test, questionaire
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Alexandra Miriam Kiess
Unspecified Childhood Solid Tumor, Protocol Specific
Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00070473
- Testing
- pemetrexed disodium
- Where
- 20 sites in United States, Canada
- Volunteers
- 33 people
- Sponsor
- Children's Oncology Group
Psychiatric Disorders, Neurodevelopmental Disorders
CYP2D6 Pharmacogenetics in Risperidone-Treated Children
Risperidone is an important medication used to treat children with psychiatric illnesses or neurodevelopmental disorders, such as autism. Despite excellent symptom control, the potential for side effects is worrisome.
- Trial name
- NCT00783783
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cancer, Hematologic Disorders
Catheter Resistance Monitoring to Predict Catheter-Associated Adverse Events in Children and Adolescents
Catheter occlusion and dysfunction are common complications of central venous access device (CVAD) use in children with cancer and hematologic disorders.
- Trial name
- NCT01737554
- Testing
- Catheter Resistance Monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- St. Jude Children's Research Hospital
Obesity, Overweight
Development of Melt Organic Baking Fat for Reducing Child Obesity
The purpose of this study is to compare the effects of a cooking oil on metabolic rate, appetite, and metabolic risk markers.
- Conditions
- Obesity, Overweight, Pediatric Obesity
- Trial name
- NCT02346994
- Testing
- Melt Test Blend 3.2, Corn Oil
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Resistance Exercise, Muscle Hypertrophy
Muscle Adaptations in Children and Adults Following Twelve Weeks of Flywheel or Weight Stack Resistance Exercise
The goal of this trial is to compare resistance exercise using traditional techniques and flywheel training to controls in healthy children ages nine to 13 and adults ages 18 to 50.
- Conditions
- Resistance Exercise, Muscle Hypertrophy, Skeletal Muscle, EMG
- Trial name
- KidREx (NCT06698055)
- Testing
- Flywheel Resistance Exercise, Weight Stack Resistance Exercise
- Where
- Sweden
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Björn Alkner
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