Clinical trials: Children, Adolescents
Neurodevelopmental Disorders
The Effect of Tomatis Auditory Stimulation in Children and Adolescents With NDDs
The current study aims to explore the preliminary efficacy of the Tomatis method on auditory processing in children with NDDs.
- Trial name
- TomatisOn (NCT06534515)
- Testing
- Tomatis auditory stimulation
- Where
- Romania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Depression
Reboxetine Treatment in Depressed Children and Adolescents an 8-Week, Open Study
The aim of the present study is to prospectively assess the anti-depressant effectiveness of reboxetine in children and adolescents, as compared with fluoxetine, in a randomized controlled open-label trial.
- Trial name
- NCT00426946
- Testing
- Reboxetine
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Geha Mental Health Center
Tuberculosis Infection, Household Contacts
Window Prophylaxis for Pediatric Tuberculosis Prevention Trial
The goal of this cluster-randomized controlled trial is to evaluate the effectiveness of tuberculosis preventive treatment (TPT) administered during the "window period" to prevent new Mycobacterium tuberculosis infections in…
- Conditions
- Tuberculosis Infection, Household Contacts, Children, Adolescent
- Trial name
- TB-WIN (NCT07086820)
- Testing
- Tuberculosis window prophylaxis with weekly rifapentine and isoniazid for 12 weeks, Standard of care tuberculosis prophylaxis with weekly rifapentine and isoniazid for 12 weeks
- Where
- 13 sites in Chile
- Volunteers
- 647 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Executive Dysfunction, Autism Spectrum Disorder
A Hybrid Effectiveness-implementation Trial of a High School-based Executive Function Treatment for Autistic Youth
This study will test the effectiveness of a school-based cognitive behavioral executive function (EF) intervention, Unstuck \& On Target High School (UOT:HS), for transition-age youth with autism spectrum disorder (ASD).
- Conditions
- Executive Dysfunction, Autism Spectrum Disorder, Adolescent Behavior
- Trial name
- NCT05017779
- Testing
- Unstuck & On Target: High School, Treatment as Usual
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Children's National Research Institute
Major Depressive Disorder
Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents
To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).
- Trial name
- NCT02586688
- Testing
- Active NeuroStar® Transcranial Magnetic Stimulation (TMS)
- Where
- 13 sites in United States
- Volunteers
- 112 people
- Sponsor
- Neuronetics
Breast Cancer
Long-Term Effect of Adolescent Diet on Hormones and Breast Cancer Risk in Women Previously Enrolled in the Dietary Intervention Study in Children
RATIONALE: The amount and type of fat in the diet may affect hormone levels, bone mineral density, and breast density later in life. This may affect the risk of developing breast cancer.
- Trial name
- NCT00458588
- Testing
- physiologic testing, questionnaire administration, breast imaging study
- Where
- 10 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2)
MiniMed Fit Payload Wear Pediatric Study
The purpose of this study is to assess MiniMed Fit Payload adhesive components in different wear locations over a 7-day period to support development of the future commercialized patch pump in participants 7-17 years of age.
- Conditions
- Diabetes (DM), Diabetes (Insulin-requiring, Type 1 or Type 2), Diabetes in Children, Diabetes in Adolescence
- Trial name
- NCT07675161
- Testing
- MiniMed Fit Payload adhesive components
- Where
- 5 sites in United States
- Volunteers
- 59 people
- Sponsor
- Medtronic MiniMed, Inc.
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Comorbid anxiety disorders affect as many as 80% of youth with autism spectrum disorders, causing substantial distress and impairment over and above the autism spectrum diagnosis alone.
- Trial name
- NCT01177969
- Testing
- Cognitive-Behavioral Therapy, Wait-list
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Syncope, Vasovagal
The Effectiveness of Metoprolol in the Prevention of Syncope Recurrence in Children and Adolescents
The purpose of this study to evaluate the effectiveness of metoprolol versus conventional treatment in the prevention of syncope recurrence in children and adolescents.
- Trial name
- NCT00475462
- Testing
- metoprolol, conventional treatment
- Volunteers
- 28 people
- Sponsor
- Peking University First Hospital
Psychiatric Disorders
Changes Following Inpatient Child-oriented Family Treatment
Children receiving IFT (intensive family therapy) were assessed for symptom profile and global functioning before admission, 3 months after discharge and 1 year after discharge.
- Trial name
- NCT00184327
- Testing
- Intensive family therapy - inpatient, Diagnostic assessment - child and adolescent psychiatry
- Where
- 5 sites in Norway
- Volunteers
- 150 people
- Sponsor
- Norwegian University of Science and Technology
Autism Spectrum Disorder
A Prospective, Single-Center, Single-Arm, Investigator-Initiated Exploratory Clinical Trial to Assess the Safety of Repetitive Transcranial Magnetic Stimulation for Children and Adolescents With Autism Spectrum Disorder
This is a prospective, single-center, single-arm, investigator-initiated exploratory clinical trial aimed at evaluating the safety and exploring the efficacy of a medical electromagnetic stimulator delivering low-frequency…
- Trial name
- NCT06982586
- Testing
- Repetitive transcranial magentic stimulation
- Volunteers
- 18 people
- Sponsor
- Bundang CHA Hospital
Advanced Sarcoma
A Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adults With Advanced Sarcoma
Phase I, open label, prospective, single-center, non-randomized, dose escalation clinical trial aiming to determine the dose-limiting toxicity (DLT) and maximum tolerated dose (MTD) of systemic transduced donor-derived NKG2D-CAR…
- Trial name
- CAR4SAR (NCT06087341)
- Testing
- NKG2D-CAR memory T cell
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Antonio Pérez Martínez
Child Development Disorders, Pervasive
RUPP PI PDD: Drug and Behavioral Therapy for Children With Pervasive Developmental Disorders
This 24-week study will compare the safety and effectiveness of medication treatment alone (risperidone or aripiprazole) to medication treatment in combination with a parent management training program.
- Trial name
- NCT00080145
- Testing
- Risperidone, Behavior Therapy
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- Yale University
Tourette Syndrome, Obsessive Compulsive Disorder
Developmental Phenomenology of Obsessive Compulsive Disorder and Tourette Syndrome in Children and Adolescents
OBJECTIVES: I. Characterize the natural history, associated features, and severity of symptoms of obsessive compulsive disorder and Tourette syndrome in children and adolescents. II.
- Trial name
- NCT00004324
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Center for Research Resources (NCRR)
Autistic Disorder
An Evaluation of Low Level Laser Light Therapy for Autistic Disorder
The purpose of this study is to determine whether the Erchonia HLS Laser is effective in the treatment of irritability associated with autistic disorder in children and adolescents aged five (5) to seventeen (17) years.
- Trial name
- NCT03379662
- Testing
- Erchonia HLS Laser
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Erchonia Corporation
Social Anxiety Disorder
RESCCUE4 - Group CBT for Social Anxiety in Adolescents
This randomized controlled trial aims to evaluate the efficacy of a 2-month group Cognitive Behavioral Therapy (CBT) intervention compared to a structured psychoeducational treatment as usual (TAU) in adolescents diagnosed with…
- Trial name
- NCT07464561
- Testing
- Group Cognitive Behavioral Therapy, Psychoeducational Group Intervention
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Primary Cardiomyopathy, Dilated Cardiomyopathy
Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
RIKADA is a prospective study performing systematic family screening including clinical and genetic testing in pediatric patients with primary cardiomyopathy and their first-degree relatives with the aim to facilitate risk…
- Conditions
- Primary Cardiomyopathy, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Left Ventricular Noncompaction
- Trial name
- RIKADA (NCT03572569)
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- German Heart Institute
Attention Deficit Hyperactivity Disorder
Neurofeedback and Computerized Cognitive Training in Different Settings for Children and Adolescents With ADHD
Attention deficit/hyperactivity disorder (ADHD) is among the most common childhood-onset psychiatric disorders, with a negative and long-lasting impact on academic achievement, social integration and quality of life.
- Trial name
- NCT02358941
- Testing
- Neurofeedback training, Computerized cognitive training
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- University of Zurich
Autism Spectrum Disorders
Investigating Phenotypic Profiles of Children and Adolescents With ASD
The purpose of this study is to provide a detailed description of language and cognitive profiles found among children and adolescents diagnosed with autism spectrum disorders (ASD).
- Trial name
- Phenotyping (NCT02700113)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston University Charles River Campus
HIV-1, HIV Infections
A Phase 2 Study to Evaluate Pharmacokinetics, Safety and Efficacy of TMC114/Ritonavir (Rtv) in Human Immunodeficiency Virus (HIV)-1 Infected Children and Adolescents
The purpose of this study is to evaluate the pharmacokinetics (the study of the way a drug enters and leaves the blood and tissues over time), safety, tolerability and antiviral activity to support dose recommendations of TMC114…
- Trial name
- NCT00355524
- Testing
- TMC114, Ritonavir
- Where
- 22 sites in United States, Argentina and 6 more
- Volunteers
- 80 people
- Sponsor
- Tibotec Pharmaceuticals, Ireland
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