Clinical trials: Children, Adolescents
Overweight, Obesity
Safety & Efficacy of Omega-3 Fish Oil in Overweight Children & Adolescents
Children with an excess in body weight, increase the risk of obesity-related co-morbidities and cardiovascular diseases. Childhood obesity may be due to diets laden with fat and lack of physical activity.
- Trial name
- NCT00447291
- Testing
- Supplement: Omega-3 Fish Oil, Multi-Disciplinary Nutrition & Exercise program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Heart Center
HIV-1
Nutritional and Metabolic Disorders in HIV Infected Children and Adolescent
The advent of highly active antiretroviral treatment has resulted in the survival into adolescence of an increasing proportion of infants and children with perinatal HIV infection in Senegal.
- Trial name
- NCT01771562
- Where
- 2 sites in Senegal
- Volunteers
- 330 people
- Sponsor
- ANRS, Emerging Infectious Diseases
22Q11.2 Deletion Syndrome
Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome (INSPIRE)
To evaluate the safety and tolerability of ZYN002 administered as a transdermal gel formulation, for up to 38 weeks, in participants ages 4 to <18 years, in the treatment of 22q.11.2 Deletion syndrome (22qDS).
- Trial name
- INSPIRE (NCT05149898)
- Testing
- ZYN002
- Where
- 3 sites in United States, Australia
- Volunteers
- 20 people
- Sponsor
- Harmony Biosciences Management, Inc.
Cachexia; Cancer, Muscle Wasting
Muscle Wasting in Children and Adolescents With Cancer
The series of the 3-year study aims to explore parents' experience of caring for a child's weight change among parents of children and adolescents with cancer, examine the associations and trends among muscle wasting and…
- Conditions
- Cachexia; Cancer, Muscle Wasting, Child Development, Adolescent Development
- Trial name
- NCT04353063
- Testing
- Multidisciplinary care with a personalized care
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- National Taiwan University Hospital
Anxiety Disorders, Depression
Pharmacogenomics of Antidepressant Response in Children and Adolescents
This study will identify variations in genes that may be involved in the development of suicidal events or certain behaviors in youth who are exposed to antidepressant medications.
- Conditions
- Anxiety Disorders, Depression, Eating Disorders, Obsessive-Compulsive Disorder
- Trial name
- PARCA (NCT00516932)
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Duke University
Obsessive Compulsive Disorder, Autism Spectrum Disorder
Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series
The aim of this study is to test the feasibility and acceptability of an internet-delivered cognitive behavior therapy (ICBT) intervention originally developed for neurotypical adolescents with obsessive compulsive disorder (OCD)…
- Trial name
- NCT02660099
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- 2 sites in Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Metabolic Syndrome Obesity
Melatonin Levels and the Relation to Obesity and the Metabolic Syndrome in Children and Adolescents
Background: Melatonin is a neurohormone that regulates the circadian rhythm by translating photoperiodic information from the eyes to the brain.
- Trial name
- NCT03316989
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Hyperkinetic Disorder, Depressive Disorder
Mindfulness and Relaxation Interventions in Individual Psychotherapies for Children and Adolescents
The study 'Mindfulness and Relaxation interventions in Individual Training Psychotherapies for Children and Adolescents' (MARS-CA) aims to examine the effects of short session-introducing interventions with mindfulness elements…
- Conditions
- Hyperkinetic Disorder, Depressive Disorder, Anxiety Disorder
- Trial name
- MARS-CA (NCT04034576)
- Testing
- Cognitive behavior therapy of trainee therapists
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Heidelberg University
Odontology
Physiological and Oral Dental Parameters of Young Child
The aim of this study is to measure some oral and maxillofacial physiological parameters, with a view to creating a modular prototype articulator from young children to adolescents by 3D printing.
- Trial name
- PhyDentchild (NCT03620214)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- CHU de Reims
Malnutrition, HIV/AIDS
Nutritional Rehabilitation in Senegalese HIV-infected Children and Adolescents
Severe (SAM, Body Mass Index-z < -3) and moderate (MAM, -3 ≤ BMI-z < -2) acute malnutrition, highly prevalent in HIV-infected children and adolescents, is an independent risk factor of death, even when antiretroviral treatment…
- Trial name
- SNAC'S (NCT03101852)
- Testing
- Plumpy Nut, Plumpy Sup
- Volunteers
- 185 people
- Sponsor
- Institut de Recherche pour le Developpement
Autism Spectrum Disorder
KONTAKT Australia a Social Skills Group Training for Adolescents on the Autism Spectrum
This study evaluates the KONTAKT social skills group training in Australian adolescents on the autism spectrum compared to an active control group which is a group cooking class
- Trial name
- NCT03294668
- Testing
- KONTAKT Australia, Super Chef
- Where
- Australia
- Volunteers
- 90 people
- Sponsor
- Curtin University
Child
Reliability and Validity of Turkish Version of PEM-CY
The Participation and Environment Measure for Children and Youth (PEM-CY) is the first instrument that combines parental assessment of children's participation in home, school, and community activities with qualities of each…
- Trial name
- NCT02485314
- Testing
- Participation
- Where
- Turkey (Türkiye)
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity
Prehabilitation in Childhood Soft Tissue or Bone Sarcomas
This study aims to investigate the feasibility of a prehabilitative training intervention. The intervention includes specific strength and balance exercises during neoadjuvant chemotherapy with children and adolescents diagnosed…
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- Prehab4Kids (NCT06743958)
- Testing
- Exercise intervention
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Relapsed or Refractory Solid Tumors
A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)
The main purpose of this study is to evaluate the antitumor activity and safety of lenvatinib (MK-7902/E7080) in children, adolescents, and young adults with relapsed or refractory solid malignancies after administration.
- Trial name
- E7080-G000-231 (NCT04447755)
- Testing
- Lenvatinib
- Where
- 49 sites in United States, Argentina and 18 more
- Volunteers
- 127 people
- Sponsor
- Merck Sharp & Dohme LLC
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Hypnotherapy vs. Probiotics in Children With IBS and Functional Abdominal Pain
Current study aims to investigate the influence of gut-directed hypnotherapy and probiotic nutritional supplement (SymbioLact B) on gastrointestinal symptoms in children with functional abdominal pain or irritable bowel syndrome…
- Trial name
- NCT02613078
- Testing
- Gut-Directed Hypnotherapy, Nutritional Supplement, Self-Monitoring
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Tuebingen
Anxiety, Depression
Connecticut Child STEPs
Connecticut Child STEPS is a randomized controlled trail investigating the effectiveness of MATCH-ADTC in treating anxiety, depression, trauma, and/or behavioral problems in children seeking services at four Department of…
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03153904
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, and Conduct Problems, Monitoring and Feedback System
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Harvard University
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06878326
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autistic Disorder
Motor Learning and Brain Changes in Autism
The purpose of this pilot study is to determine whether a video-game based motor training can affect postural stability, daily living skills, autism symptoms, and white matter microstructure of the corticospinal tract in…
- Trial name
- NCT02358317
- Testing
- Video Game Motor Training, Sedentary Video Game Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Laparoscopic Cholecystectomy
Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
The objective of this study is to compare transversus abdominis plane (TAP) blocks to local wound infiltration (LWI) in terms of postoperative pain control in pediatric patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03022279
- Testing
- TAP Blocks, local wound infiltration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Brian Wallace Gray
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