Clinical trials: Children
Celiac Disease in Children, Celiac Disease in Adolescents
Effect of Adherence to a Gluten-Free Diet on Cognitive and Motor Dual-Task Performance in Adolescents Diagnosed With Celiac Disease
The aim of this cross-sectional observational study is to comprehensively examine the effects of adherence to a gluten-free diet on cognitive, motor, and psychosocial functions in adolescents aged 8-18 years diagnosed with celiac…
- Trial name
- NCT07382999
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Disaster Preparedness, Health Education
The Effect of Health Belief Model-Based Disaster Education for Parents of Children With Special Needs on General Disaster Preparedness Beliefs and Disaster Preparedness Levels
This study aims to evaluate the effect of a Health Belief Model (HBM)-based disaster education program on general disaster preparedness beliefs and disaster preparedness levels among parents of children with special needs.
- Conditions
- Disaster Preparedness, Health Education, Child With Special Health Care Needs, Parents Who Have Special Needs Children
- Trial name
- NCT07810608
- Testing
- Health Belief Model -Based Disaster Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Celiac Disease in Children
Prevention of Celiac Disease in Skåne
This study aims to investigate the impact of being on a gluten free diet the first three years of life compared to a daily intake of a probiotic supplementation or placebo on the risk of developing celiac disease autoimmunity or…
- Trial name
- PreCiSe (NCT03562221)
- Testing
- Gluten free diet, Probiotics
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lund University
Inferior Alveolar Nerve Block in Children
Clinical Success of 12 mm Needle IANB in Children
This prospective single-arm pilot study will evaluate the clinical success of an inferior alveolar nerve block performed using a 12 mm 30-gauge extra-short dental needle in children aged 4 to 12 years.
- Trial name
- NCT07791082
- Testing
- 12 mm 30-Gauge Extra-Short Dental Needle
- Where
- Egypt
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Child Behavior, Life Skill Development
Improving School Climate and Children's Well-being Through the Life Skills "Feel Good" Intervention in French Schools: A Controlled Before-and-After Study
Life skills are major determinants of health that can be influenced through health promotion initiatives. Numerous educational interventions exist to foster the development of life skills.
- Conditions
- Child Behavior, Life Skill Development, School Health, School
- Trial name
- FEEL GOOD (NCT07804940)
- Testing
- FEEL GOOD
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université Paris Cité
Healthy Children, CP (Cerebral Palsy)
Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game
This study is testing ways to help children with cerebral palsy (CP) improve how their hands work. Investigators want to see if brain activity using a virtual reality (VR) program can make their hands work better.
- Conditions
- Healthy Children, CP (Cerebral Palsy), CP, Cerebral Palsy
- Trial name
- NCT06818877
- Testing
- Brain-Computer Interface (BCI)-HABIT-VR, Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Rheumatic Heart Disease in Children
Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children
This study will look at whether children ages 5-8 who take Penicillin V by mouth twice a day are less likely to develop rheumatic heart disease (RHD) over a 3-year period compared to children who do not take the medicine.
- Trial name
- MEERCATS 2 (NCT07798232)
- Testing
- Oral Penicillin V
- Where
- Uganda
- Volunteers
- 9,622 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Anxiety in Children
AI-Assisted Evaluation of Dental Anxiety in Children: A Machine Learning Approach
This observational study evaluated whether children's dental anxiety could be identified from their speech using artificial intelligence and machine learning methods.
- Trial name
- NCT07797777
- Testing
- Multimodal Speech-Based Dental Anxiety Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Marmara University
Malnutrition in Children
Impact of School Meal Program on Child Nutrition and Academic Performance
This study will assess the impact of a school meal program on the nutritional status and academic performance of primary school children in Lahore, Pakistan.
- Trial name
- NCT07800208
- Testing
- School Meal Program
- Where
- Pakistan
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Allergies, Obesity
Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring
Allergy prevalence is increasing steadily with some describing as the "epidemic of the twenty-first century". Maternal diet during pregnancy has been linked to offspring allergy risk, so it represents a potential target for…
- Conditions
- Allergies, Obesity, Gestational Complications, Gestational Weight Gain
- Trial name
- PREMEDI (NCT05119868)
- Testing
- Nutritional intervention based on Mediterranean Diet
- Where
- 2 sites in Italy
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Federico II University
Mental Health, Violence Against Children
Palestinian ParentText for Crisis: A Parenting Chabot in War and Displacement
The primary aim of this research is to evaluate if ParentText for Crisis helps improve the following outcomes among Palestinian caregivers living in Jordan: a.) Improving caregiver mental health; b.) Improving positive parenting…
- Conditions
- Mental Health, Violence Against Children, Parenting
- Trial name
- NCT07494786
- Testing
- ParentText for Crisis
- Where
- Jordan
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Language Impairment, Autism
Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language Impairment
This study will pilot a newly developed Syntactic-Semantic Visual Configuration Intervention (SSVCI) designed to help Urdu-speaking children with language impairment improve their ability to understand and produce phrases and…
- Conditions
- Language Impairment, Autism, Hearing Impaired Children, Down Syndrome
- Trial name
- SSVC-PILOT (NCT07786545)
- Testing
- Syntactic-Semantic Visual Configuration Intervention (SSVCI)
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Children's Anxiety Levels, Children's Behavior
The Effect of Vibration Devices on Pain and Discomfort During Local Anesthesia Administration in Children
This split-mouth randomized clinical trial will be conducted at the Department of Pediatric Dentistry, King Abdulaziz University Dental Hospital (KAAUDH).
- Conditions
- Children's Anxiety Levels, Children's Behavior, Physiological Changes (Heart Rate), Obejective Pain and Discomfort
- Trial name
- NCT07384923
- Testing
- DentalVibe intraoral vibration device, Buzzy Bee® extraoral vibration device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Visual Function, Vision
Visual Function Screening System With Special Needs Children and Typical Preschoolers
The early visual screening of children plays a critical role in promoting visual development, especially for those with visual impairments.
- Conditions
- Visual Function, Vision, Special Needs Children
- Trial name
- NCT07081139
- Testing
- observational study, no interventional
- Where
- Taiwan
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose…
- Conditions
- Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension
- Trial name
- POPS or POP02 (NCT04278404)
- Testing
- The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Dental Anxiety in Children, Behavior Management
AI-Generated Personalized Story Book to Improve Patient Behaviour
Dental anxiety and uncooperative behavior frequently interfere with the successful delivery of dental treatment in children and may increase the need for pharmacological behavior management.
- Conditions
- Dental Anxiety in Children, Behavior Management, Pediatric Dental Anxiety
- Trial name
- AI-STORY (NCT07778134)
- Testing
- AI-Generated Personalized Dental Storybook, Standard Dental Storybook, Standard Behavior Guidance
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Children, Adolescents
Exercise and Endocannabinoids for Brain and Mental Health
This study will explore how exercise affects brain chemicals called endocannabinoids, which may improve thinking skills and reduce feelings of stress, anxiety, and low mood in children and teens aged 9 to 17.
- Trial name
- EMBH (NCT06808490)
- Testing
- Moderate Intensity Exercise, Light Intensity Stretching, Seated Meditation
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Malnutrition in Children, Children Exposed to HIV
A Trial Testing a Two-way SMS Platform to Recognize and Prevent Wasting Among HIV-infected and HIV-exposed Uninfected Children in Kenya
The goal of this study is to test if a two-way text-message (SMS) maternally administered malnutrition monitoring system (MAMMS) that delivers infant and young child feeding (IYCF) education and supports caregivers in monitoring…
- Trial name
- MAMMS IYCF R33 (NCT06842732)
- Testing
- Maternal Administered Malnutrition Monitoring System - Infant and Young Child Feeding (MAMMS IYCF) intervention, Standard of Care (SOC)
- Where
- 2 sites in Kenya
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- University of Washington
Constipation, Children
Influence of Body Position on the Defecation Model During Anorectal Manometry.
Anorectal 3D manometry (3D HRAM) is the most advanced version of manometric equipment that measures pressures along the anal canal in a very detailed manner.
- Conditions
- Constipation, Children, Anorectal Disorder
- Trial name
- HRAMposition (NCT06924957)
- Testing
- 3D HRAM
- Where
- Poland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Procedural Pain, Anxiety
Effects of Robotic Pet and Video-Based Distraction on Pain, Fear, and Anxiety in Children During Venipuncture
The goal of this randomized controlled clinical trial is to evaluate the effects of robotic pet and video-based distraction on pain, fear, and anxiety in children aged 5-10 years undergoing venipuncture.
- Conditions
- Procedural Pain, Anxiety, Procedural Fear in Children
- Trial name
- RCT (NCT07763730)
- Testing
- Robotic Pet-Based Distraction, Video-Based Distraction
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Akdeniz University