Clinical trials: Children
Fever, Children
Effect of Buzzy and Virtual Reality on Children Undergoing Venous Procedures
Throughout the diagnostic and treatment process, pediatric patients are subjected to invasive procedures-such as peripheral intravenous catheterization (PIVC)-that cause pain, stress, fear, and anxiety.
- Trial name
- NCT07882602
- Testing
- Vein-imaging device + virtual reality headset group, Vein-imaging device + Buzzy group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Bandırma Onyedi Eylül University
Endotracheal Aspiration, Tracheostomy Patients
Classical Music, Pain, and Physiological Parameters in Children Undergoing Two Aspiration Procedures
Intensive care units (ICUs) are high-technology, high-performance units where patients with life-threatening conditions receive advanced nursing care and continuous monitoring.
- Conditions
- Endotracheal Aspiration, Tracheostomy Patients, Children
- Trial name
- NCT07882615
- Testing
- Classical Music Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Bandırma Onyedi Eylül University
Children With Hemiplegic cp
Virtual Reality Vs Postural Control Training in Children With Cerebral Palsy
The goal of this clinical trial is to learn if there is difference between the effect of virtual reality and postural control training on balance and gait in children with hemiplegic cerebral palsy.
- Trial name
- NCT07884552
- Testing
- Virtual reality, Postural control training
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Amira Mahmoud Abdelkader Mohamed
Sickle Cell Anemia in Children
Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE)
This study will 1) Evaluate the prevalence of elevated (conditional or abnormal) transcranial Doppler (TCD) velocities in a cross-sectional analysis of children with Sickle Cell Anemia (SCA) living in Tanzania; 2) Obtain…
- Trial name
- NCT03948867
- Testing
- Hydroxyurea, Elevated Arm TCD Examination, Normal Arm TCD Examination
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 202 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Caries in Children, Dental Plaque
Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases
The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can…
- Conditions
- Dental Caries in Children, Dental Plaque, Tooth Decay, Periodontitis
- Trial name
- LumoPrevent (NCT06286501)
- Testing
- Lumoral Treatment, Standard, personalized oral health care
- Where
- Finland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wellbeing Services County of Pirkanmaa
Allergy in Children
Long Term Effect of AIT in Children
The present study will investigate the long term effect of allergen immunotherapy in a real-life study in children with allergy undergoing subcutaneous or sublingual immunotherapy with grass pollen, birch, house dust mites or…
- Trial name
- NCT06421415
- Testing
- Allergen Immunotherapy Extract
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Peanut Allergies in Children
Evaluation of a Supervised Clinical Feeding Intervention
Peanut allergies affect approximately 2.5% of children; are associated with significant mortality, morbidity, and economic costs; and often lead to persistent peanut allergies in adulthood.
- Trial name
- NCT06892132
- Testing
- Supervised feeding intervention, Handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Osteosarcoma Recurrent, Osteosarcoma in Children
Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma
The goal of this clinical trial is to define the maximum tolerated dose (MTD) and/or Recommended phase 2 dose (RP2D) of Tegavivint in combination with Gemcitabine in patients with relapsed or refractory osteosarcoma (OS).
- Conditions
- Osteosarcoma Recurrent, Osteosarcoma in Children, Relapsed Osteosarcoma, Refractory Osteosarcoma
- Trial name
- NCT07144254
- Testing
- Tegavivint, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Healthy Children
Physical and Psychosocial Outcomes of 16-Week Classroom-Based Morning Exercise Program
The overall goal of the project is to enhance the physical and emotional well-being of primary school-aged children by incorporating short exercises-practicable within the classroom setting right at their desks-into their daily…
- Trial name
- NCT07860983
- Testing
- Classroom-Based Morning Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Dietary Intakes, Physical Activity
Implementing Modified Practices to Leverage Evidence for Movement, Engagement, and Nutrition Topics in Early Childcare and Education
The goal of this cluster-randomized, controlled trial is to learn if a professional development program for childcare educators, called the Boston Healthy Child Care Initiative, can help improve the nutritional quality of…
- Conditions
- Dietary Intakes, Physical Activity, Child Care, Early Education
- Trial name
- IMPLEMENT (NCT07874295)
- Testing
- Boston Healthy Child Care Initiative
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Tracheal Intubation in Children
Ambu Aura-i and Air-Q Intubating Laryngeal Airways as a Conduit for Tracheal Intubation in Children
The purpose of this study is to determine whether there is a clinically relevant difference in time to tracheal intubation when using fiberoptic bronchoscope as a guide to intubate through the Ambu Aura-i or air-Q ILA.
- Trial name
- NCT01535742
- Testing
- Ambu Aura-i size 1.5, air-Q ILA size 1.5, Ambu Aura-i size 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Laryngeal Mask Airway in Children
A Comparison of the Laryngeal Mask Airway (LMA) - Unique and LMA-Supreme in Children
The aim of this randomized prospective study is to compare two single-use laryngeal mask airways the LMA Unique and the LMA Supreme, in pediatric patients.
- Trial name
- NCT01653795
- Testing
- LMA Unique: control device, LMA Supreme: comparison device
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Healthy Children, Children With Neurodevelopmental Disorders
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
Background: During the first few decades of life, the brain changes dramatically in shape and function. Sleep lets researchers measure these changes.
- Conditions
- Healthy Children, Children With Neurodevelopmental Disorders, Children With Neuropsychiatric Disorders, Children With Behavioral Syndromes
- Trial name
- NCT04639830
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Migraine in Children
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
To find out if eptinezumab is better than placebo (normal saline solution) in lowering the number of days with migraine in young people ages 12 to 17 with chronic migraine.
- Trial name
- PROSPECT-2 (NCT04965675)
- Testing
- Eptinezumab
- Where
- 79 sites in United States, Argentina and 9 more
- Volunteers
- 285 people
- Sponsor
- H. Lundbeck A/S
Cardiac Disease, Critically Ill
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
OPTIC is a prospective, open-label, non-randomized study of multiple medications administered to approximately 2000 children in the pediatric cardiac intensive care unit (PCICU) per routine clinical car by their treating…
- Conditions
- Cardiac Disease, Critically Ill, Children, Adult
- Trial name
- OPTIC (NCT05055830)
- Testing
- The OPTIC study is collecting PK data on children prescribed understudied drugs of interest per standard of care.
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Duke University
Reversal of Local Anesthesia in Children
Phentolamine Mesylate vs. Diode Laser for Anaesthesia Reversal
"Randomised three-arm trial comparing phentolamine mesylate (OraVerse), 650-nm diode laser and no intervention for accelerating reversal of soft-tissue anaesthesia after 4% articaine (1:100,000 epinephrine) buccal infiltration in…
- Trial name
- RCT (NCT05473858)
- Testing
- OraVerse Injectable Product, diode laser
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- sara nabil
Chronic Kidney Failure in Children and Young Adults
Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients
Recent trials have demonstrated positive renal outcomes of sodium-glucose co-transporter-2 inhibitors (SGLT2i) additive to angiotensin-converting-enzyme inhibitors (ACEis) in adult patients with diabetic and non-diabetic chronic…
- Trial name
- DOUBLE_PROTECT (NCT05944016)
- Testing
- Dapagliflozin
- Where
- 16 sites in Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Goettingen
Rural Left-Behind Children, Social Adaptation
Music Therapy for Character Development and Social Adaptation Among Rural Left-Behind Children
Rural left-behind children (LBC) are children in rural China whose parents have migrated to cities for work. They often face emotional and social difficulties because of long-term separation from parents.
- Conditions
- Rural Left-Behind Children, Social Adaptation, Character Development
- Trial name
- MT-LBCCDSA (NCT07877961)
- Testing
- Group Music Therapy, Psychoeducational Lectures
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shangqiu Normal University
Hearing Loss, Bilateral or Unilateral, Otitis Media With Effusion in Children
Towards Implementation of Universal Newborn Hearing Screening in Kenya
The goal of this observational study is to learn if smartphone hearing screening devices can help to understand the role of ear infections in hearing loss in infants with HIV exposure.
- Trial name
- mTUNE-R33 (NCT07879326)
- Testing
- Hearing and ear health screening
- Where
- Kenya
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Children With Disabilities
Feasibility Trial of Family-Centered Therapeutic Dance for Children With Disabilities
The primary aim of this exploratory cluster-randomized trial is to assess the feasibility and acceptability of delivering a school-based group therapeutic dance program through a family-centered approach for children with…
- Trial name
- DanceDiversity (NCT07166055)
- Testing
- Therapeutic dance
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valencia