Clinical trials: Children, completed
Surgery, Noise Exposure
The Effect of a Reduced Noise Environment on Induction and Emergence Behavior in Children Undergoing General Anesthesia
This project will investigate whether reduction in ambient light and elimination of noise on induction of anesthesia alters anxiety (modified Yale Preoperative Anxiety Scale or mYPAS) or compliance (induction compliance checklist…
- Trial name
- NCT03504553
- Testing
- Noise reduction
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Joshua Uffman
Brainstem Glioma
A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas
This study evaluated the effect of capecitabine and concomitant radiation therapy in children with newly diagnosed brainstem gliomas.
- Trial name
- NCT01118377
- Testing
- Capecitabine, Radiation therapy
- Where
- 8 sites in United States
- Volunteers
- 45 people
- Sponsor
- Hoffmann-La Roche
Malaria
In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children (MEFI_III)
This is a classical in vivo clinical trial, following World Health organization's recommendations, ran as a multisite study within Mozambique trying to assess the efficacy and safety in 4 sites of the two oral ACTS…
- Trial name
- MEFI_III (NCT04370977)
- Testing
- Coartem™ (Artemether-lumefantrine combination), Winthrop™ (Amodiaquine-artesunate combination)
- Where
- 6 sites in Mozambique
- Volunteers
- 630 people
- Sponsor
- Centro de Investigacao em Saude de Manhica
Autism Spectrum Disorder
The Effect of Digital Storytelling and Sensory Integration on Children With Autism
Given the interest of children with Autism Spectrum Disorder (ASD) in using computers, this study examined the effect of Digital Storytelling (DST) activity on increasing activity participation and self-regulation.
- Trial name
- NCT06491875
- Testing
- Digital Storytelling (DST), Sensory Integration Therapy (SIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Biruni University
Spastic Cerebral Palsy
The Effects of Functional Strengthening in Spastic Cerebral Palsy
Functional strengthening exercises have been proven to be effective in patients with spastic cerebral palsy. However, which exercise is the most effective is unknown.
- Trial name
- NCT03901703
- Testing
- Physiotherapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Melek Volkan Yazici
Gastrointestinal Diseases
DIAMANTE - Diseases Infectious Analysis Microflora Antibiotic Effect
To assess the effects of Bacillus clausii (Enterogermina®) on fecal microbial flora (using Polymerase Chain Reaction - Denaturing Gradient Gel Electrophoresis - PCR-DGGE - Method) in antibiotic-treated children with complicated…
- Trial name
- NCT00424905
- Testing
- Bacillus clausii
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Sanofi
Bipolar Disorder
Safety and Efficacy of Ziprasidone in Children and Adolescents With Bipolar I Disorder (Manic or Mixed)
The purpose of this study is to determine if flexibly-dosed ziprasidone is safe and effective for the treatment of children and adolescents (ages 10-17) with bipolar I disorder (manic or mixed).
- Trial name
- NCT00257166
- Testing
- Ziprasidone oral capsules
- Where
- 50 sites in United States
- Volunteers
- 238 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Child Development Disorder
Craniosacral Test and Primitive Reflexes in Infant Neurodevelopment
Question(s): Can active primitive reflexes (APR) and cranial blocks (CB) in healthy children interfere with neurological balance causing psycho-behavioral and cognitive dysfunctions? Design: Cross-sectional and descriptive study…
- Trial name
- NCT05190029
- Testing
- Series of questions to parents of children in a virtual form., Intervention by teachers, Physiotherapeutic evaluation
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Clinica Gema Leon
Iron Overload
Risk Factors and Measures to Prevent Liver and Pancreas Complications in Pediatric Patients After HSCT
Hematopoietic Stem Cell Transplantation (HSCT) is currently a standard procedure for a wide range of blood-oncological diseases and genetic disorders.
- Trial name
- NCT04423237
- Testing
- Deferasirox
- Where
- Italy
- Volunteers
- 39 people
- Sponsor
- University of Pisa
Neurofibromatosis 2, Vestibular Schwannoma
Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors
The purpose of this study is to determine if Lapatinib has any effect on tumors found in patients with Neurofibromatosis Type 2 (NF2). NF2 is a condition that mainly affects the skin and nervous system.
- Trial name
- NCT00973739
- Testing
- Lapatinib
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Hematopoietic Cell Transplantation Recipient, Malignant Neoplasm
High Dose Flu Vaccine in Treating Children Who Have Undergone Donor Stem Cell Transplant
This phase II randomized trial studies how well high dose flu vaccine works in treating children who have undergone done stem cell transplant.
- Conditions
- Hematopoietic Cell Transplantation Recipient, Malignant Neoplasm, Influenza
- Trial name
- NCT02860039
- Testing
- Trivalent Influenza Vaccine, Quadrivalent Influenza Vaccine, Laboratory Biomarker Analysis
- Where
- 9 sites in United States
- Volunteers
- 170 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Preoperative Fasting
Gastric pH in Intubated Children
Fasting (according to ASA, ESA or institutional guidelines) is an important strategy to minimize the risk of regurgitation, vomiting and pulmonary aspiration during general anaesthesia; the effect of fasting time for clear fluid…
- Trial name
- NCT01516775
- Testing
- clear fluid ingestion
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Achim Schmitz
Autism Spectrum Disorder, Social Communication
Joint Attention-Based Occupational Therapy Intervention in Pre-Schoolers With Autism Spectrum Disorder
In order to support the development of preschool children, joint attention training with activities incorporated in their natural routines can support the achievement of occupational therapy goals.
- Conditions
- Autism Spectrum Disorder, Social Communication, Behavior Problem, Visual Perceptual Weakness
- Trial name
- NCT05106166
- Testing
- Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Malnutrition
Trial to Alleviate Malnutrition With Fortified Spread Given as a Food Supplement to Underweight Infants
This study tests the hypothesis that underweight 6-17-month old infants receiving fortified spread as a food supplement for 12 weeks grow better during the supplementation than infants who are provided with maize-soy flour…
- Trial name
- NCT00131222
- Testing
- Food supplement: fortified spread, Food supplement: maize and soy flour
- Where
- Malawi
- Volunteers
- 176 people
- Sponsor
- Tampere University
Allergic Asthma
Efficacy Of Bacterial Lysate In Asthmatic Children
This study evaluate the efficacy of Mechanical Bacterial Lysate (PMBL - Ismigen®) to improve the asthma control level (ACT score) as add-on treatment to routine asthma treatment in children aged 6 to 16 with uncontrolled or…
- Trial name
- EOLIA (NCT02541331)
- Testing
- ISMIGEN
- Where
- 4 sites in Poland
- Volunteers
- 150 people
- Sponsor
- Lallemand Pharma AG
Amblyopia
Trial Comparing Atropine to Atropine Plus a Plano Lens for the Sound Eye for Amblyopia in Children 3 to <7 Years Old
The purpose of the study is: To compare the effectiveness and safety of weekend atropine augmented with a plano lens for the sound eye versus weekend atropine alone for moderate amblyopia (20/40 to 20/100) in children 3 to less…
- Trial name
- ATS8 (NCT00315302)
- Testing
- Atropine, Plano Lens
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Jaeb Center for Health Research
Full Mouth Rehabilitation, Canine Overlap Relation
Canine Occlusal Relationship Changes After Stainless-Steel Crown Placement Under General Anesthesia
The aim of the study is to Assess and compare canine occlusal relation in children with carious primary molars before they are treated by stainless steel crowns under general anaesthesia and after their placement, evaluate the…
- Conditions
- Full Mouth Rehabilitation, Canine Overlap Relation, General Anesthesia
- Trial name
- NCT04731337
- Testing
- Digital Caliper (Shenzhen Jiabaili Electronic Commerce Co., Ltd)
- Where
- Egypt
- Volunteers
- 178 people
- Sponsor
- Cairo University
Disruptive Behavior, Aggression Childhood
Digital Parent Training for Disruptive Behaviors in Children
This is an open pilot trial of web-based parent training for tantrums and disruptive behavior in children. Parents will be asked to complete a battery of tests to assess their children' behaviors before and after the…
- Conditions
- Disruptive Behavior, Aggression Childhood, Anger, Non-Compliance, Patient
- Trial name
- NCT03697837
- Testing
- Parent Management Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Cleft Lip and Palate, Social Isolation
Perception of Appearance and Social Acceptance Between Cleft and Non-Cleft Children in Early Adolescence
Background: Using three-dimensional (3D) surface imaging, this study aims to understand the differences in perception between schoolchildren with and without cleft lip and palate (CLP), as well as to explore peer awareness and…
- Trial name
- Cleft social (NCT06539572)
- Testing
- Cleft lip repair; palatoplasty; alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Retinopathy of Prematurity (ROP)
Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP)
The main purpose of this study is to evaluate the long-term efficacy and safety outcomes following short-term exposure to rhIGF-1/rhIGFBP-3 versus standard neonatal care in Study ROPP-2008-01 (NCT01096784).
- Trial name
- PEDAL (NCT02386839)
- Testing
- rhIGF-1/rhIGFBP-3
- Where
- 16 sites in United States, Italy and 4 more
- Volunteers
- 76 people
- Sponsor
- Shire