Clinical trials: Children - Malnutrition
Severe Acute Malnutrition, Severe Wasting
Soy-Ready to Use Therapeutic Food (RUTF) in Severely Malnourished Children
SAM defined by having weight-for-height (WH) less than - 3 Z score or bi-pedal nutritional edema is an important cause of death in children globally including Bangladesh.
- Conditions
- Severe Acute Malnutrition, Severe Wasting, Community Based Nutritional Management
- Trial name
- NCT01634009
- Testing
- Soy-based RUTF (in double blind design)
- Where
- Bangladesh
- Volunteers
- 260 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Moderate Acute Malnutrition (MAM)
Supplementary Food on Prevention of Moderate Malnutrition in Children
The study will evaluate the impact of a supplementary food (cookies) in preventing the risk of developing moderate acute malnutrition (MAM) in preschool mildly malnourished children.
- Trial name
- NCT02572258
- Testing
- Nutritional cookie
- Where
- Mexico
- Volunteers
- 1,048 people
- Sponsor
- PepsiCo Global R&D
Malnutrition
Effectiveness Trial on Alleviation of Infant Malnutrition With Fortified Spread or Maize-Soy Flour Food Supplements
This study tests the hypothesis that moderately underweight but not severely wasted 6-17-month old infants receiving fortified spread or maize-spy flour as a food supplement for 12 weeks grow better during the supplementation…
- Trial name
- NCT00420758
- Testing
- Food supplement: fortified spread, Food supplement: maize-soy flour
- Where
- Malawi
- Volunteers
- 299 people
- Sponsor
- Tampere University
Children, Malnutrition
Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition
This project is being conducted with an aim to find out energy expenditure, body composition and recovery rates in children with severe acute malnutrition (SAM) receiving community-based nutritional rehabilitation therapy
- Trial name
- NCT01144806
- Testing
- Nutrition education, RUTF
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Aga Khan University
Dietary Exposure, Diabetes Mellitus, Type 2
Cohort Study on Plant-based Diets (COPLANT Study)
The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria.
- Conditions
- Dietary Exposure, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Bone Loss
- Trial name
- COPLANT (NCT06323538)
- Where
- 8 sites in Austria, Germany
- Volunteers
- 6,000 people
- Sponsor
- German Federal Institute for Risk Assessment
Diarrhoea;Infectious;Presumed, Diarrhea, Infantile
Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa
This project is a community-based randomized controlled trial designed to test the effectiveness of two point-of-use water treatment technologies to improve clean drinking water access, reduce enteropathogen burden, and improve…
- Conditions
- Diarrhoea;Infectious;Presumed, Diarrhea, Infantile, Diarrhea Tropical, Environmental Exposure
- Trial name
- NCT03012048
- Testing
- Silver-impregnated ceramic tablet, Silver-impregnated ceramic water filter, Safe-storage water container
- Where
- South Africa
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diarrhoea, Severe Malnutrition
Oral Rehydration SolutionContaining Amylase Resistant Starch in Severely Malnourished Children.
Severe malnutrition is associated with a high rate of mortality, even when using the latest WHO recommendations. Watery diarrhea as observed in cholera is an additional vital risk to those children.
- Trial name
- NCT00324285
- Testing
- Amylase resistant starch added ORS
- Where
- Bangladesh
- Volunteers
- 180 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Type 1 Diabetes Mellitus, Vitamin D Deficiency
Vitamin D Supplementation and Glycemic Control Improvement Among Type 1 Diabetic Children
Type 1 diabetes mellitus (T1DM) is an immune-mediated disease characterized by diminished insulin secretion due to damage to islets of Langerhans in the pancreas, which eventually results in high levels of glucose in the blood.
- Trial name
- NCT05141968
- Testing
- vitamin D supplements (2000 IU/day)
- Where
- Palestinian Territories
- Volunteers
- 80 people
- Sponsor
- Al-Azhar University
Malnutrition, Child
Study of Malnutrition in Primary School Children
Study of malnutrition in primary school age children aim to asses the prevelance of malnutrition amoung the children in this age group and also ldintified the factors that affect in malnutrition between the children and the study…
- Trial name
- NCT04810468
- Testing
- Anthropometric measurment
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Sohag University
Malnutrition, Child
Prevalence of Intestinal Parasitic Infections in Under-Five Children With Malnutrition in Sohag, Egypt
This study aims to estimate the prevalence of intestinal parasitic infections in under-five children with malnutrition.
- Trial name
- NCT06716060
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Vitamin D Deficiency
Vitamin D Serum Concentrations & Supplementation in Children With Cerebral Palsy
The purpose of this study is to try to correlate vitamin D dosing and dosing adjustment with Vitamin D levels, measure affects of seizure medications on levels as well as pathologic fractures and bone density in severely…
- Trial name
- NCT01926808
- Volunteers
- 115 people
- Sponsor
- Akron Children's Hospital
Child Nutrition Disorders
Evaluating the Relative Effectiveness of Two Feeding Interventions for the Treatment of Moderate Acute Malnutrition
Supplementary feeding programs for children with moderate acute malnutrition have been implemented in developing countries using treatment foods with minimal or no evidence of their effectiveness.
- Trial name
- NCT01097889
- Testing
- Fortified blended foods, Corn Soya Bean Flour (CSB) with oil., RUSF (ready-to-use supplementary foods) Supplementary Plumpy®
- Where
- 2 sites in Canada, Ethiopia
- Volunteers
- 2,600 people
- Sponsor
- The Hospital for Sick Children
Tuberculosis, Pulmonary
Impact of Malnutrition on Pharmacokinetic of Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK)
TB-Speed TB-PK is a cross-sectional PK study of anti-TB treatment nested in the TB-Speed HIV and TB-Speed SAM studies aiming at assessing the impact of malnutrition on PK of rifampicin, isoniazid, pyrazinamide, and ethambutol in…
- Trial name
- NCT04972903
- Where
- 4 sites in Uganda, Zambia
- Volunteers
- 85 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
X-linked Hypophosphatemia
Using Different Doses of Active Vitamin D Combined With Neutral Phosphate in Children With X-linked Hypophosphatemia
X-linked hypophosphatemia (XLH) is the most common form of heritable rickets. Current treatments include active vitamin D metabolites (e.g. calcitriol) and phosphate salts.
- Trial name
- NCT03820518
- Testing
- Calcitriol
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Malnourished Children
Effects of Channa Striata Extract on Intestinal Inflammation and Nutritional Status in Malnutritional Toddlers After Albendazole Therapy in South Bangka District
The goal of this clinical trial is to learn if intervention with channa striata extract or inbumin forte sachet as a food supplement can improve intestinal damage and nutritional status in malnourished children aged 1.5-5 years.
- Trial name
- Striatin1 (NCT06933862)
- Testing
- Striatin
- Where
- 2 sites in Indonesia
- Volunteers
- 122 people
- Sponsor
- Universitas Indonesia
Depression, Postpartum, Malnutrition, Child
Decreasing Stunting by Reducing Maternal Depression in Uganda: A Cluster Randomized Controlled Trial (CRCT) for Improved Nutrition Outcomes
The project seeks to test the integration of Interpersonal Psychotherapy for Groups within Care Group projects and investigate whether the treatment of maternal depression with Interpersonal Psychotherapy for Groups improves the…
- Trial name
- NCT03573713
- Testing
- Care Groups, IPT-G
- Where
- Uganda
- Volunteers
- 1,248 people
- Sponsor
- Food for the Hungry