Clinical trials: Children Development
Autism Spectrum Disorder
Study 1 Replication and Extension of Prior Work
The goal of this research is to explore abilities to learn word meanings from overheard conversations in children with ASD (and, as a control, typically developing children).
- Trial name
- NCT04166591
- Testing
- Overheard Speech, Addressed Speech
- Where
- 2 sites in United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- New York University
Autism, Autism Spectrum Disorder
Intensive Intervention for Toddlers With Autism (EARLY STEPS)
Goals of the current project: (1) Does the Early Start Denver Model experimental intervention for toddlers with autism reduce disability associated with autism significantly more than standard community interventions?; and (2)…
- Trial name
- NCT00698997
- Testing
- Early Start Denver Model, Standard community care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of California, Davis
Fragile X Syndrome, Autism Spectrum Disorders
Acamprosate in Youth With Fragile X Syndrome
Fragile X syndrome (FXS) is the most common inherited form of developmental disability. FXS is inherited from the carrier parent, most often the mothers.
- Trial name
- NCT01300923
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Risk Assessment, Online Intervention
Early Childhood Outside (ECO) - Randomized Controlled Trial Study
Outdoor play is important for children as it can promote healthy social and physical development, emotional well-being, self-confidence, risk management and overall physical activity.
- Conditions
- Risk Assessment, Online Intervention, Child Development
- Trial name
- NCT04624932
- Testing
- RR Digital Tool, Position Statement on Active Outdoor Play
- Where
- Canada
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Autism Spectrum Disorder
Oxytocin and Social Cognitive Skills Groups
The purpose of this study is to evaluate the feasibility, safety, and preliminary efficacy of integrating targeted dosing of intranasal oxytocin with a social cognitive skills group therapy for school-aged children with autism…
- Trial name
- ION-ASD (NCT02918864)
- Testing
- Oxytocin, Social Cognitive Skills Training, Facilitated Play Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder
Effect of Virtual Reality-based Training on Balance and Walking in Youth With Autism Spectrum Disorder
The goal of this clinical trial is to assess the effect of short-term (3 days/week for 2 weeks) Virtual Reality (VR) active video gaming intervention on static and dynamic balance, versus traditional balance training exercises…
- Trial name
- NCT06023563
- Testing
- Virtual reality active video gaming using Nintendo switch sports, Standard physical therapy balance exercises
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Indiana University
Autism
Autologous Cord Blood Stem Cells for Autism
Evaluate the efficacy of one infusion of stem cells from autologous umbilical cord blood in patients with autism over six months after infusion as measured by changes in expressive and receptive language.
- Trial name
- NCT01638819
- Testing
- Autologous Cord Blood Stem Cells
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sutter Health
Autism Spectrum Disorder
Effect of a 9-Month Internship Intervention for Military Dependents With ASD
The aims of the project are: 1. VCU will modify the Project SEARCH Plus ASD Model to meet the needs of military dependents with ASD. 2.
- Trial name
- NCT04001790
- Testing
- Project Search plus ASD Supports
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Craniosynostosis, Bleeding
Tranexamic Acid for Craniofacial Surgery
This is a randomized, blinded, prospective study that will investigate the potential benefit of tranexamic acid to reduce the intraoperative bleeding and blood transfusions in pediatric patients undergoing craniofacial surgeries.
- Trial name
- NCT00722436
- Testing
- Tranexamic acid, saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Idiopathic Growth Hormone Deficiency, Turner Syndrome
First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study
PREDICT Validation is a validation pharmacogenetic trial. The purpose of this study is to confirm that some genes can be used to predict how well a subject diagnosed with idiopathic growth hormone deficiency (IGHD) or turner…
- Trial name
- NCT01419249
- Testing
- Blood sampling
- Where
- 31 sites in Argentina, Canada and 7 more
- Volunteers
- 458 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Autism, Autism Spectrum Disorder
A Lead-in Study Evaluating Efficacy of GuessWhat Mobile App Therapy for Children With Autism
The following study aims to assess the efficacy, safety data, and best outcome measurements of the mobile game platform, GuessWhat, in delivering behavioral therapy to children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT04739982
- Testing
- GuessWhat Mobile App
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorders
Gaming for Autism to Mold Executive Skills Project
The goal of the project is to better understand executive control-how children manage complex or conflicting information in the service of a goal.
- Trial name
- GAMES (NCT02361762)
- Testing
- Computerized executive control training
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Developmental Language Disorder, Specific Language Impairment
Retrieval-based Word Learning in Developmental Language Disorder: Adaptive Retrieval Schedule
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06995014
- Testing
- Retrieval-based word learning: Standard retrieval practice schedule, Retrieval-based word learning: Adaptive retrieval practice schedule
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Purdue University
Divorce
An Internet Based Adaptation of a Divorce Intervention Beginnings Program for Divorced Parents
This study is a two-armed randomized controlled trial of the eNew Beginnings Program (eNBP)'s effects on children's mental health problems as well as interparental conflict, parent-child relationship quality and effective…
- Trial name
- NCT05209932
- Testing
- Online New Beginnings Program (eNBP)
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Family Transitions: Programs that Work
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 6, who have been diagnosed with moderate to severe autism.
- Trial name
- TPBMASD (NCT04660552)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder
Extension for Community Healthcare Outcomes Autism Replication Evaluation
ECHO Autism was intended to assess rigorously the impact of a 12-session telemedicine training program on participating Primary Care Providers (PCP) knowledge, clinical behavior, and self-efficacy in the screening and care of…
- Trial name
- ECHO Autism (NCT03677089)
- Testing
- 12 ECHO Autism telehealth clinics
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Growth Hormone Deficiency
Safety and Efficacy Study of MOD-4023 to Treat Children With Growth Hormone Deficiency
Treatment of children with growth failure due to growth hormone deficiency (GHD). Primary • To evaluate the efficacy and safety of weekly MOD-4023 administration compared to daily Genotropin® administration in Japanese…
- Trial name
- NCT03874013
- Testing
- MOD-4023, Genotropin
- Where
- 46 sites in Japan
- Volunteers
- 44 people
- Sponsor
- OPKO Health, Inc.