Clinical trials: Children With Autism
Autism Spectrum Disorder
Intermittent Theta-Burst Stimulation to Target Irritability in Adults With ASD
This study aims to demonstrate the feasibility, tolerability, safety and preliminary efficacy of 6 weeks of fMRI-guided iTBS delivered to personalized regions of the prefrontal cortex (PFC) in adults with ASD in reducing…
- Trial name
- NCT04316338
- Testing
- Intermittent theta-burst stimulation (iTBS)
- Sponsor
- Stanford University
Schizophrenia, Autism-Related Irritability
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents
- Trial name
- NCT07424404
- Testing
- KarXT, KarX-EC
- Where
- 104 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Autistic Disorder
Study of Fluoxetine in Adults With Autistic Disorder
This is a study to determine the effect of fluoxetine in the treatment of adult autism and on functional ability and behavior associated with autism. Evidence suggests abnormal serotonin function in autism.
- Trial name
- NCT00027404
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
A Study of Glutathione in Children With Autism Spectrum Disorder
The aim of this study is to investigate if taking a supplement called Glutathione by mouth is safe and practical for children and teenagers with Autism Spectrum Disorder (ASD).
- Trial name
- NCT05954052
- Testing
- Glutathione
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Chicago
Autism Spectrum Disorder
Improving Transition Outcomes for Youth With ASD in a Medicaid Accountable Care Organization
Despite an increasing number of children with Autism Spectrum Disorder (ASD), fragmentation across child and adult service systems results in poor education, employment and health outcomes for transition-aged youth (TAY).
- Trial name
- NCT04869540
- Testing
- Usual care, 'Got Transition' toolkit and resources, PSE intervention
- Sponsor
- Boston Medical Center
Autism Spectrum Disorder
Autologous Umbilical Cord Blood Infusion for Children With Autism Spectrum Disorder (ASD)
This study is a prospective phase 1 single-center trial designed to determine the safety of a single intravenous infusion of autologous umbilical cord blood in children with Autism Spectrum Disorder (ASD) and assess the…
- Trial name
- NCT02176317
- Testing
- Autologous Umbilical Cord Blood
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Autism Spectrum Disorder
Efficacy and Safety of Functional Neurogenesis Stimulation Therapy in Children With Autism Spectrum Disorder (ASD)
This study will test whether a noninvasive brain stimulation treatment called Functional Neurogenesis Stimulation (using the NeuroCytontron device) can safely improve core symptoms of Autism Spectrum Disorder (ASD) in children.
- Trial name
- NCT07276555
- Testing
- Functional Neurogenesis Stimulation Therapy
- Where
- 2 sites in United States, Mexico
- Volunteers
- 256 people
- Sponsor
- Neurocytonix, Inc.
Autism Spectrum Disorder
Sensory Integration Versus Fine Motor Intervention in Children With Autism
Clinically, infants with Autism spectrum often display gross motor delays in supine, prone, and sitting skills in their first year of life.
- Trial name
- NCT04696133
- Testing
- fine motor skills, sensory integration
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S.
- Trial name
- NCT02839915
- Testing
- Folinic Acid
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder
Parenting a Child With Autism Spectrum Disorder and Marital Status
The purpose of this study is to investigate whether the presence of a child with Autism Spectrum Disorder places parents at increased risk for divorce.
- Trial name
- NCT01435733
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Single-dose
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT04278898
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Child Development Disorders, Pervasive
Randomized Trial of Parent Training for Young Children With Autism
The purpose of this 24 week study is to determine whether a new Parent Training program is effective in reducing disruptive behaviors in young children with pervasive developmental disorders.
- Trial name
- RUBI (NCT01233414)
- Testing
- Parent Training, Psychoeducational Program
- Where
- 6 sites in United States
- Volunteers
- 180 people
- Sponsor
- Yale University
Autism
Toe Spread Out Exercise With and Without Walking Surface Training in Children With Autism
Flatfoot is a common postural deformity in children, characterized by the collapse of the medial longitudinal arch, leading to abnormal foot posture, gait disturbances, and postural instability.
- Trial name
- NCT07438665
- Testing
- Toe spread out exercise, Toe spread out exercises with walking surface training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Autism
Pilot Study of Diet and Behavior in Children With Autism
We hypothesize that in children with autism dietary antigens can change the intestine, making it "leaky" and then affecting the brain changing their behavior.
- Trial name
- NCT01625299
- Testing
- Gluten and dry milk
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center, Houston
Social Communication Disorder, Autism
Feasibility Trial of Parent-delivered Social Communication Program
The Hanen Centre®'s More Than Words® (MTW) program is a globally used, parent coaching intervention delivered by speech-language pathologists (SLPs) to parents of children with social communication challenges, including those who…
- Trial name
- NCT06847347
- Testing
- More Than Words®
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Western University, Canada
Autistic Disorder
Evaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With Autism
This study will determine the effectiveness of aripiprazole and D-Cycloserine in treating symptoms associated with autism in children.
- Trial name
- NCT00198107
- Testing
- Aripiprazole, D-cycloserine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Indiana University
Tuberous Sclerosis Complex, TSC Related Cognitive Disability
Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a genetic disease that leads to mental retardation in over 50% of patients, and to learning problems, behavioral problems, autism and epilepsy in up to 90% of patients.
- Conditions
- Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning Problems
- Trial name
- RAPIT (NCT01730209)
- Testing
- Everolimus
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Autism Spectrum Disorder
Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD)
ASD is a diverse disorder starting in early childhood and characterized by social communication impairment as well as restricted interests and repetitive behaviors.
- Trial name
- NCT02561481
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Cancer, Oncology
Seen and Be Heard: Ensuring Fair Cancer Care for All Children
Introduction: Research has routinely been conducted into the experiences and well-being of children and young people with cancer and their families.
- Conditions
- Cancer, Oncology, Haematological Malignancy
- Trial name
- NCT06481527
- Volunteers
- 50 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Autism Spectrum Disorder (ASD), Joint Attention
Joint Attention Processing in Social Threat Scenarios
This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye…
- Trial name
- NCT07582757
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
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