Clinical trials: Chills
Cardiac Arrest
Mild Versus Moderate Therapeutic Hypothermia in Out-of-hospital Cardiac Arrest Patients
This trial is currently a single-center, randomized, double-blind investigator initiated prospective clinical trial initiated at the University of Ottawa Heart Institute (UOHI).
- Trial name
- CAPITALCHILL (NCT02011568)
- Testing
- Therapeutic Hypothermia
- Where
- Canada
- Volunteers
- 389 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Febrile Shivering, Severe Bacterial Infection
Fever and Shivering: Frequency and Role in Predicting Serious Bacterial Infection
Febrile shivering in the pediatric population is assumed to be related to a Severe Bacterial Infection (SBI). Research supporting this assumption is scant.
- Trial name
- NCT02760745
- Testing
- Ancillary tests
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Respiratory Distress Syndrome, Adult, Sars-CoV2
Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS
Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of ~40%, and has no known treatment other than optimization of support.
- Trial name
- CHILL-pilot (NCT03376854)
- Testing
- Hypothermia, Neuromuscular Blocking Agents, Standard of Care
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Pollution; Exposure, Respiratory Disease
Children's Health in London and Luton (CHILL)
Investigating the impact of London's Ultra Low Emission Zone on children's respiratory health
- Conditions
- Pollution; Exposure, Respiratory Disease, Child Development
- Trial name
- CHILL (NCT04695093)
- Testing
- Ultra Low Emission Zone (ULEZ)
- Where
- United Kingdom
- Volunteers
- 3,312 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Obstructive Sleep Apnea of Adult
Safety and Dosing Study of the CHILLS Cryotherapy for the Treatment of OSA
ARCTIC-1 is a safety and dosing study to evaluate procedure tolerability in patients with clinically diagnosed moderate or severe OSA.
- Trial name
- ARCTIC-1 (NCT04864652)
- Testing
- CHILLS Procedure
- Where
- 2 sites in Panama, Paraguay
- Volunteers
- 84 people
- Sponsor
- Cryosa, Inc.
Pain, Fatigue
Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascular Disease
The coronavirus SARS-CoV-2 causing COVID-19 was pandemic since 2020. Vaccination is one of the most important measure to control the outbreak. The countries of the world started the vaccination since December, 2020.
- Conditions
- Pain, Fatigue, Headache, Myalgia
- Trial name
- NCT05033613
- Testing
- heart rate、arrhythmia、blood pressure、central body temperature (ear temperature) and blood oxygen saturation level.
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Spine Surgery, Postoperative Delirium and Chills
Scheme of Limb Warming Blanket Combined With Dexmedetomidine
Objective: To observe the clinical effect of lower limb warming blanket combined with dexmedetomidine (DEX) in preventing postoperative delirium (POD) and chills in elderly patients undergoing spinal surgery.
- Trial name
- NCT05857410
- Testing
- Dexmetomidine, Lower limb heating blanket
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Jincheng General Hospital
Marijuana Use
Project Chill: Tailored Youth Drug Intervention In Primary Care
This study examines the impact of tailored computer-delivered and therapist-delivered brief motivations prevention/interventions both for adolescents who have not initiated marijuana use (prevention), and those who use marijuana…
- Trial name
- NCT01329315
- Testing
- BMI-T, BMI-C
- Volunteers
- 1,141 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Laparoscopic Cholecystectomy
Investigation of the Intraoperative and Postoperative Effects of Warming Patients in Laparoscopic Cholecystectomy
In our study, the investigators will investigate the effects of electric blanket heating on intraoperative hemodynamics, postoperative nausea, vomiting, shivering, agitation and pain in patients undergoing laparoscopic…
- Trial name
- NCT06022926
- Testing
- warmed with electric blankets, patients without warming
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
MALARIA, FEVER
Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human Volunteers
The study is a randomized open label clinical trial to verify the reproducibility of a sporozoite challenge model for Plasmodium vivax in humans.
- Conditions
- MALARIA, FEVER, Sweating Fever, Chills
- Trial name
- NCT00367380
- Testing
- 413ABM, 414WRR, 418JAL
- Where
- Colombia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Malaria Vaccine and Drug Development Center
Respiratory Distress Syndrome, Adult
Trial of Therapeutic Hypothermia in Patients With ARDS
Acute Respiratory Distress Syndrome (ARDS) is a serious condition that occurs as a complication of medical and surgical diseases, has a mortality of ~40%, and has no known treatment other than optimization of support.
- Trial name
- CHILL (NCT04545424)
- Testing
- Hypothermia, Neuromuscular Blocking Agents, Standard of care
- Where
- 19 sites in United States
- Volunteers
- 340 people
- Sponsor
- University of Maryland, Baltimore
Intracranial Stenosis, Intracranial Atherosclerotic Disease
Endovascular Recanalization for Symptomatic Chronic Intradural Occlusions
Background: Chronic intracranial large vessel occlusion (LVO), resulting from progressive atherosclerosis or thrombosis, contributes significantly to ischemic strokes, 8-10% in North America and up to 50% in the Chinese…
- Trial name
- Re-CHILL (NCT07072026)
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 80 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Obstructive Sleep Apnea of Adult
Pilot Study of the CHILLS Cryotherapy System for the Treatment of OSA
This is a prospective, multicenter, non-randomized single-arm safety and efficacy study to: Collect data to evaluate the safety of CHILLS cryotherapy to treat OSA in patients with moderate to severe disease.
- Trial name
- ARCTIC-2 (NCT05542082)
- Testing
- CHILLS Procedure
- Where
- 2 sites in Panama
- Volunteers
- 22 people
- Sponsor
- Cryosa, Inc.
Acute Ischemic Stroke, Basilar Artery Occlusion
Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
This study will examine whether cooling part of the brain through a catheter after endovascular treatment improves recovery in adults with acute basilar artery occlusion, a type of severe stroke.
- Trial name
- NCT07896655
- Testing
- Mechanical thrombectomy, Normothermic saline infusion, 4°C saline infusion
- Where
- 2 sites in China
- Volunteers
- 818 people
- Sponsor
- Guangdong Second Provincial General Hospital
Chills
Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
comparison of Dexmedetomidine And Ketamine For Control Of Shivering In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia.
- Trial name
- NCT05481281
- Testing
- Dexmedetomidine, Ketamine
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Stress, Anxiety
A Clinical Study of De-Stress & Chill Gummies in Reducing Stress
The current study focuses on clinical validation of efficacy of nutraceutical product in reduction of stress,anxiety and improving mood in adults.
- Trial name
- NCT06571071
- Testing
- De-Stress and Chill Gummies-U001, De-Stress and Chill Gummies-I001
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Herbolab India Pvt. Ltd.
Cardiogenic Shock
Cardiogenic Shock Intravascular Cooling Trial
The purpose of the study is to compare patients with cardiogenic shock who receive standard therapy plus therapeutic hypothermia (TH) to patients with cardiogenic shock who receive standard medical therapy alone in order to…
- Trial name
- CHILL-SHOCK (NCT03141255)
- Testing
- IVTM™ System, Quattro® Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Acute Pancreatitis (AP)
A Trial of the Arctx Cool Catheter in Acute Pancreatitis
Researchers will compare people who get the ACC Set plus standard of care to people who get standard of care alone. This will show whether adding the ACC Set helps.
- Trial name
- CHILL-AP (NCT07698119)
- Testing
- Treatment, Control
- Volunteers
- 200 people
- Sponsor
- Arctx Medical, Inc.
Temperature Change, Body, Chills
Does Higher OT Temperature and IV Ondansetron Reduce Incidence of PSS in Parturients?
This study will look at the incidence of post-spinal shivering (PSS) among the obstetrics population and will investigate whether higher operation theater (OT) temperature range or/and IV Ondansetron are able to reduce the…
- Conditions
- Temperature Change, Body, Chills, Tremor, Nausea, Postoperative
- Trial name
- HOTON (NCT04654429)
- Testing
- IV Ondansetron 4mg, Higher OT temperature range, Lower OT temperature Range
- Where
- Malaysia
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Dr Lim Siu Min