Clinical trials: Chinese
Healthy
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of HFB30132A Against COVID-19 in Chinese Healthy Adults
The purpose of this study is to examine the safety and tolerability of HFB30132A when it is given by single intravenous infusion in Chinese healthy participants.
- Trial name
- NCT05275660
- Testing
- HFB30132A
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HiFiBiO Therapeutics
Healthy
A Clinical Study of MK-7962 in Healthy Chinese Participants (MK-7962-021)
The goal of this study is to learn about the safety of 2 different amounts of sotatercept and if healthy Chinese people tolerate them.
- Trial name
- NCT06843460
- Testing
- Sotatercept
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Metabolic Disorders, Non-alcoholic Steatohepatitis
A Study to Understand the Safety, Tolerability, and Activity of Drug in Body Over a Period of Time of AZD2693, in Subjects of Non-Childbearing Potential in Overweight But Otherwise Healthy Subjects, and Healthy Chinese and Japanese Subjects
This Phase 1, first-in-human (FiH), single-ascending-dose (SAD) study, will assess the safety and tolerability and characterize the pharmacokinetics (PK) of AZD2693, following subcutaneous (SC) SAD administration of AZD2693 in…
- Trial name
- NCT04142424
- Testing
- AZD2693
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Primary Dysmenorrhea (PD)
Individualized Acupoint Therapy for Dysmenorrhea: An Exploratory Research Design Based on Meridian Measurement
Primary dysmenorrhea is a common condition that significantly affects young women's quality of life. Traditional Chinese Medicine (TCM) acupoint interventions are widely used for symptom relief; however, standardized…
- Trial name
- NCT07818044
- Testing
- TI-816-3E3 Portable Laser Phototherapy Device
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Healthy
Multiple Dose Bioequivalence Study of Pramipexole Extended Release in Chinese Healthy Male Volunteers
To establish bioequivalence at steady state of: 1)0.375 mg pramipexole extended release tablet q.d. in fasted status versus 0.125 mg pramipexole Immediate release tablet t.i.d.
- Trial name
- NCT01214109
- Testing
- pramipexole extended release, pramipexole immediate release
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Osteoporosis Fracture
Height Loss, Kyphosis Indicators, Bone Mineral Density and Vertebral Fractures in Chinese Postmenopausal Women
This is an observational and cross-sectional study on the height loss, kyphosis indicators, bone mineral density and vertebral fractures in Chinese postmenopausal women
- Trial name
- NCT03798444
- Testing
- dual energy X-ray absorptiometry, lateral spine imaging from T4 to L4 on X-ray
- Where
- China
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Central South University
Healthy Subjects, Plasma Concentration of Mirabegron
A Study to Evaluate Absorption, Distribution and Elimination of Mirabegron After Oral Administration to Non-elderly Healthy Chinese Subjects
The purpose of this study is to evaluate safety and absorption, distribution and elimination of mirabegron after oral administration to Chinese subjects.
- Trial name
- NCT01747564
- Testing
- YM178 (mirabegron)
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Healthy
A Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of THDB0206 Injection in Healthy Chinese Subjects
This is a single-center, single-dose, open-label, positive-controlled, randomized, three-cycle, crossover 8-hour euglycemic clamp study to evaluate the PK, PD, safety and tolerability of THDB0206 injection after subcutaneous…
- Trial name
- NCT06153329
- Testing
- THDB0206 injection, Humalog®, BC222insulin lispro injection
- Where
- China
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Tonghua Dongbao Pharmaceutical Co.,Ltd
Myopia
Effect of Vision Therapy in Myopic Children With Poor Accommodative Response
This study aims to determine the treatment effect of vision therapy on myopic children by assessment of accommodative function before and after therapy.
- Trial name
- NCT03006601
- Testing
- Office-based accommodative/vergence therapy
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Healthy Adult Participants
Safety, Tolerability, and Pharmacokinetic Evaluation of ADB116 for Injection
A Phase I Study of ADB116 for Injection in Healthy Chinese Adults. This study aims as follows: Primary Objective: To evaluate the safety and tolerability of a single intravenous bolus dose of ADB116 for injection in healthy…
- Trial name
- NCT07729839
- Testing
- ADB116 for Injection
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jiangsu Aidea Pharmaceutical Group Co., Ltd.
Healthy Male Volunteers
Study to Investigate the Mass Balance and Biotransformation of SIM0417 in Healthy Adult Chinese Male Participants
This is a non-randomized, open-label, single-dose, Phase I clinical study to evaluate the mass balance and biotransformation, safety and tolerability of SIM0417 in healthy Chinese adult male subjects following a single oral…
- Trial name
- NCT05475834
- Testing
- SIM0417
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Dyslipidemia
The Effect of a Plant Sterols-Enriched Low-Fat Milk on Lipid Profile in Healthy Southern Chinese (COME-PASS)
This is a randomized, double-blind, single-center, two-arm, placebo-controlled clinical trial that examine the effect of the consumption of a plant sterols-enriched low-fat milk.
- Trial name
- COME-PASS (NCT02541201)
- Testing
- Plant sterols-enriched low-fat milk, Low-fat milk
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Healthy Volunteers
Study of Food Effects of VV913 Capsules in Chinese Healthy Volunteers
This study is a single-center, randomized, open label, 3×3 crossover design to assess the high-fat meal and the standard meal effects on PK of a single oral dose of VV913 in healthy adult volunteers.
- Trial name
- NCT07565792
- Testing
- VV913
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Primary Biliary Cholangitis
Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS0159 in Chinese Healthy Subjects
This is a phase I clinical bridging trial, randomized, double-blind, placebo-controlled, single ascending does/ mulelple ascending does study of CS0159 to evaluate the safety, tolerability, pharmacokynetics, pharmacodynamices…
- Trial name
- NCT05624294
- Testing
- CS0159
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cascade Pharmaceuticals, Inc
Intradialytic Hypotension
The Clinical Study of Improving the Thirst and Hypotension of Hemodialysis Patients
This clinical study is to observe the improvement of MHD (maintenance hemodialysis) patients, quality of life，after applying therapy combining Auriculotherapy and Shengmai capsule.
- Trial name
- NCT02583802
- Testing
- Ear pills, Shengmai capsule
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beijing University of Chinese Medicine
Overweight, Obesity
Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin
The purpose of this study is to characterize the Influence of HDM1005 on gastric emptying and drug-drug interaction of HDM1005 and metformin, atorvastatin, warfarin, and digoxin in overweight/obese adult subjects.
- Trial name
- NCT07502001
- Testing
- Acetaminophen, Metformin, Warfarin
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Breast Implantation
Breast Fat Grafting Augmentation in Chinese Women
A total of 38 Chinese healthy women underwent autologous fat grafting for cosmetic breast augmentation. Breast volumes were measured by magnetic resonance imaging preoperatively and 1 year after the procedure.
- Trial name
- NCT02551939
- Testing
- Autologous Fat Grafting
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Healthy Volunteers (HV)
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of KR25102 in Healthy Volunteers
Phase 1 Single Ascending Doses(SAD): Six cohorts of 53 healthy volunteers (HVs) will receive a single IV bolus injection of study drug or placebo.
- Trial name
- NCT07618156
- Testing
- KR25102 for Injection
- Where
- China
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Jiangxi Kvvit Pharmaceutical Co., Ltd.
Healthy Volunteer
A Pharmacokinetic Study of RO4917838 in Healthy Chinese Volunteers
This single-center, open-label, single dose, randomized, two-way cross-over study will evaluate the pharmacokinetics, safety and tolerability of RO4917838 in healthy Chinese volunteers.
- Trial name
- NCT01433575
- Testing
- RO4917838
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy Subjects
Pharmacokinetics and Bioequivalence of Rivaroxaban Tablet in Healthy Chinese Volunteers
The study was designed as a single-site, randomized, open-label, four-period complete and replicate crossover. A single oral dose of 20 mg rivaroxaban tablet (test) and Xarelto®(reference) was given to the 72 healthy Chinese…
- Trial name
- NCT04424381
- Testing
- Rivaroxaban 20 MG Oral Tablet [Xarelto], Rivaroxaban 20 MG Oral Tablet
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
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