Clinical trials: Chinese
Risk Assessment of Chronic Atrophic Gastritis Malignant Transformation
Risk Assessment and Syndrome Evolution Models for Chronic Atrophic Gastritis Malignant Transformation
Chronic atrophic gastritis (CAG) is acknowledged as the precancerous stage of gastric cancer (GC). The present study aims to developed risk assessment and syndrome evolution models of CAG malignant transformation events combining…
- Trial name
- NCT03261934
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Beijing University of Chinese Medicine
Healthy Male Subjects
A Clinical Trial of XZP-3287 for Material Balance
A single-centre, open-label, mass balance and biotransformation study in healthy male subjects utilising a single oral dose of [14C] XZP-3287
- Trial name
- NCT05478109
- Testing
- [14C]XZP-3287
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xuanzhu Biopharmaceutical Co., Ltd.
Bicuspid Aortic Valve (BAV)
A Study of Chinese Congenital Bicuspid Aortic Valve
Pervious studies indicated that the prevalence of bicuspid aortic valve（BAV） might be higher in China. There is a familial predisposition to the development of BAV.
- Trial name
- NCT06802016
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Metastatic NSCLC
Use of Chinese Herbal Formula Shu Yu Wan in Lung Cancer Patients
The purpose of this study is to evaluate whether Chinese Herb supplements lead to a measurable improvement in symptoms commonly experienced by patients with advanced stage lung cancer and an improvement in quality of life.
- Trial name
- CH:II (NCT04615884)
- Testing
- Chinese herbs formula: Shu Yu Wan
- Where
- Canada
- Sponsor
- Lady Davis Institute
Systemic Lupus Erythematosus
A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants
This study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of GSK4527363 in healthy participants (Part A), participants with active SLE (Part B), healthy participants of Chinese and…
- Trial name
- NCT06576271
- Testing
- GSK4527363, Belimumab
- Where
- 28 sites in United States, Argentina and 4 more
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypertension
Isometric Resistance Exercise for Hypertension
Background: Isometric resistance exercises (IREs) have great potential to improve blood pressure (BP) control. However, the effectiveness of IREs in reducing HT is still unknown because their hypotensive effects have not been…
- Trial name
- NCT06510998
- Testing
- isometric wall exercise, passive stretching
- Where
- 2 sites in Hong Kong
- Volunteers
- 390 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Overweight
Effectiveness and Safety of Acupuncture for Obesity and Over-weight People
To determine the efficacy and safety of acupuncture for obesity and overweight people in China.
- Trial name
- NCT02108236
- Testing
- acupuncture
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Healthy Volunteers
A Study to Evaluate the Pharmacokinetics and Safety of Fezolinetant in Healthy Chinese Female Subjects
The purpose of this study is to evaluate the pharmacokinetics and safety of fezolinetant after single-dose and multiple dose administration in healthy Chinese female participants.
- Trial name
- NCT04793204
- Testing
- fezolinetant
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma China, Inc.
Hypertension
Blood Pressure Follow-up Study in Two Chinese Cohorts(C-BPCS)
Essential hypertension is a complex trait which results from interaction between environmental factors and genetic factors. The aim of this study is to investigate the effects of interaction between environmental factors and…
- Trial name
- C-BPCS (NCT02734472)
- Testing
- Incidence and risk factors of hypertension
- Where
- China
- Volunteers
- 5,298 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Bipolar Disorders
Bipolar Disorder With Alcoholism in Han Chinese
The aim of this study is to explore relation between the comorbidity of different bipolar disorders with alcoholism and neuropsychiatric function and candidate genes.
- Trial name
- NCT01188395
- Where
- Taiwan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Schizophrenia
A Study of rTMS for Cognitive Deficits in Chronic Patients With Schizophrenia
In this study, we assessed the therapeutic effects and safety of left dorsolateral prefrontal cortex (DLPFC) high-frequency repetitive transcranial magnetic stimulation (rTMS) on negative symptoms of schizophrenia.
- Trial name
- NCT03273439
- Testing
- repetitive TMS
- Volunteers
- 47 people
- Sponsor
- Suzhou Psychiatric Hospital
Type 2 Diabetes
A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus
This study was a multicenter, randomized, parallel and controlled study in adult patients with T2DM to evaluate the efficacy, safety (including immunogenicity) and pharmacokinetics of GZR18 injection in adult patients with T2DM.
- Trial name
- NCT06256549
- Testing
- GZR18, Semaglutide
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Threatened Miscarriage
Chinese Herbal Medicine (New "Shoutai Wan") and/or Oral Progesterone Intervention Trial for Threatened Miscarriage
Threatened miscarriage is manifested by vaginal bleeding, with or without abdominal pain, while the cervix is closed and the fetus is viable and inside the uterine cavity.
- Trial name
- NCT02633878
- Testing
- Chinese Herbal Medicine (New "Shoutai Wan") plus Oral Progesterone
- Where
- 22 sites in China
- Volunteers
- 1,656 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Bronchiectasis, Quality of Life
Evaluating the Effects of Traditional Chinese Medicine by N-of-1 Trials
Treatment based on syndrome differentiation is the essence of traditional Chinese Medicine(TCM) and forms the individualized treatment.
- Conditions
- Bronchiectasis, Quality of Life, Traditional Chinese Medicine, Sputum
- Trial name
- NCT03147443
- Testing
- Individualized Decoction, Tested drug minus heat-clearing herbs
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Idiopathic Pulmonary Fibrosis
Comparative Pharmacokinetic(PK) Study of Pirfenidone Modified-Release Tablets and Pirfenidone Tablets in Healthy Subjects Under Fed Conditions
A Randomized, Open-Label, Two-Period, Double-Crossover Comparative Study on the Pharmacokinetics of Pirfenidone Modified-Release Tablets and Pirfenidone Tablets in Healthy Chinese Subjects under Fed Conditions Primary objective…
- Trial name
- NCT06588517
- Testing
- Pirfenidone Modified-Release Tablets, Pirfenidone Tablets
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
Severe Mental Illness, Schizophrenia
The Potential Efficacy of the Chinese Health Improvement Profile- A Pilot Clustered Randomised Controlled Trial
The investigators programme of research will evaluate an existing physical health care screening intervention with the aim of helping Community Psychiatric Nurses (CPN) to improve the physical health wellbeing of people with a…
- Conditions
- Severe Mental Illness, Schizophrenia, Schizoaffective Disorder, Bipolar Affective Disorder
- Trial name
- CHIP (NCT02453217)
- Testing
- Chinese CHIP, Treatment as usual
- Volunteers
- 144 people
- Sponsor
- Wai-Tong Chien
Non-small Cell Lung Cancer Stage I
Traditional Chinese Medicine Combined With Thermal and Cold Ablation for Early-stage Lung Cancer
Lung cancer is the leading cause of cancer related mortality. At present, surgical treatment is the main choice for early-stage lung cancer. Even after surgery, the 5-year recurrence rate is still as high as 18.4%-24%.
- Trial name
- NCT05097417
- Testing
- traditional Chinese medicine and ablation in the primary tumor sites, ablation
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanghai 10th People's Hospital
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong
Hepatitis
HCV Epidemiological Survey in China Rural Area
The purpose of this study is to determine whether the morbidity of hepatitis C with Chinese population.
- Trial name
- HCVES (NCT04593355)
- Where
- China
- Volunteers
- 6,068 people
- Sponsor
- The First Hospital of Jilin University