Clinical trials: Chlorhexidine
Healthy
Components of Chlorhexidine Gluconate Dressing
The purpose of this study is to determine the contents of a chlorhexidine-containing dressing after use.
- Trial name
- NCT01112020
- Testing
- CHG Catheter Dressing Patch, Biopatch, Tegaderm CHG
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Periodontal Disease
Evaluation and Comparison of the Efficacy of Triphala Mouthwash and 0.2% Chlorhexidine
The purpose of this study is to evaluate the usefulness of triphala mouthwash in comparison with the gold standard chlorhexidine in hospitalized and periodontally diseased patients.
- Trial name
- NCT01900535
- Volunteers
- 120 people
- Sponsor
- Tatyasaheb Kore Dental College
Antisepsis
Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate ( Sorbectol )
The present study evaluates the effects of bactericidal load reduction after surgical hand antisepsis using the reference antiseptic product propanol- 1 60% as control versus a surgical hand antisepsis with addition of a solution…
- Trial name
- NCT04683146
- Testing
- Hand antisepsis with Propanolol- 1 60%., Hand antisepsis with a solution of alcohol, chlorhexidine digluconate and potassium sorbate.
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centro Ortopedico y Quirurgico del Pie
Staph Aureus Methicillin Resistant Colonization
Study of 2% Chlorhexidine Gluconate-Impregnated Bath Cloths to Prevent MRSA Colonization in Complex Continuing Care
The purpose of this study is to determine whether daily bathing with 2% chlorhexidine gluconate-impregnated antiseptic cleanser (CHG) significantly reduces incidence of colonization of hospitalized patients with…
- Trial name
- NCT01717690
- Testing
- CHG antiseptic body cleanser
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Baycrest
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Bacterial Transmission, Intubation Intratracheal
ORAL-PROTECT I: Oral Asepsis Preventing Transmission During Intubation
Postoperative respiratory complications, such as bacterial pneumonia, are common and serious problems after general anesthesia. They can lead to longer hospital stays, more complications, and increased mortality.
- Conditions
- Bacterial Transmission, Intubation Intratracheal, Chlorhexidine
- Trial name
- ORAL-PROTECT I (NCT07669064)
- Testing
- Preoperative oral decontamination with chlorhexidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Ulm
Surgical Site Infection
Comparison of Two Preoperative Antiseptic Solutions Alcohol Based in Abdominal Elective Surgeries
Pragmatic randomized clinical trial comparing Iodine Povacrylex based on alcohol to Chlorhexidine also based on alcohol in efficacy and security to diminish frequency of surgical site infections in major abdominal elective clean…
- Trial name
- NCT03859908
- Testing
- Iodine Povacrylex 7 MG/ML / Isopropyl Alcohol 0.74 ML/ML, Chlorhexidine Gluconate 20 MG/ML / Isopropyl Alcohol 0.7 ML/ML
- Where
- El Salvador
- Volunteers
- 18 people
- Sponsor
- Universidad de El Salvador
Adverse Effect
Anti-staining Efficacy of Anti-Discoloration System (ADS) Added to Chlorhexidine (CHX)
Dental staining is the most common local side effect of chlorhexidine (CHX) mouthwashes. A prospective, cross-over, randomized clinical trial will be carried out in triple blind to compare the effect on dental staining of two…
- Trial name
- CHX+ADS (NCT02709824)
- Testing
- Chlorhexidine gluconate with ADS, Chlorhexidine gluconate without ADS
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Milan
Smoking, Periodontitis
The Effect of Smoking and Chlorhexidine on Periodontal Tissues After Non- Surgical Periodontal Therapy in Patients With Periodontitis
The aim of this study is to evaluate whether the use of a chlorhexidine based oral antiseptic will improve clinical results of non-surgical periodontal therapy (NSPT) in smokers with periodontitis.
- Conditions
- Smoking, Periodontitis, Periodontal Diseases
- Trial name
- NCT06191497
- Testing
- non surgical periodontal therapy, Chlorhexidine mouthwash
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University of Rijeka
Pulp Disease, Dental
Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal
To investigate The Effect of Sodium hypochlorite and Chlorhexidine as cavity Disinfectants on the post operative pain and Success of Partial Caries Removal in deep carious lesion with moderate pulpitis in permanent teeth
- Trial name
- NCT06836882
- Testing
- Selective caries removal, Selective caries removal with NaOCl, Selective caries removal with CHX
- Where
- India
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Hip Osteoarthritis, Avascular Necrosis of Femur Head
Influence of Antiseptic Washes on Wound Healing Complications After THA
The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery.
- Trial name
- NCT07104084
- Testing
- lavage chlorhexidine, lavage povidone-iodine
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- F. Johannes Plate
Healthy
Antimicrobial Efficacy of 2% CHG (Chlorhexidine Gluconate)
Pilot study to evaluate and compare activity of preoperative preparation with comparator
- Trial name
- NCT02530541
- Testing
- CHG
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Ventilator Associated Pneumonia
Effectiveness of a VAP Prevention Bundle in the PICU
This observational monocentric prospective study aims to evaluate the efficacy of new measures for ventilator associated pneumonia (VAP) management in the pediatric population in the pediatric intensive care unit (PICU) of…
- Trial name
- NCT03763695
- Testing
- Measures for the VAP prevention in the PICU, Evaluation of VAP incidence before the protocol introduction
- Where
- Italy
- Volunteers
- 242 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hallux Valgus, Arthritis of the First Metatarsophalangeal Joint
Chloridehexidine Versus Povidine Jodine Both Soluted in Alcohol in Forefoot Surgery
The study will prospectively compare the efficacy and safety of chloride hexidine soluted in alcohol with povidine-jodine soluted in alcohol in forefoot surgery.
- Trial name
- NCT01583192
- Testing
- skin preparation
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- St. Antonius Hospital
Wound Infection Post-Traumatic, Wound Healing
Effectiveness of Chlorhexidine Impregnated Gauze Versus Povidone Iodine Dressing in Post Trauma Wound Care
To compare rate of infection and wound healing between chlorhexidine impregnated paraffin gauze and dry povidone-iodine dressings in post-traumatic wounds.
- Trial name
- NCT07456072
- Testing
- Chlorhexidine impregnated paraffin gauze, Povidone iodine dressing
- Where
- Pakistan
- Volunteers
- 176 people
- Sponsor
- Pakistan Institute of Medical Sciences
Surgical Site Infection, Cesarean Section; Infection
Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections
This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation in preventing cesarean section wound infections.
- Trial name
- NCT05920122
- Testing
- 2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution
- Where
- United States
- Volunteers
- 1,398 people, healthy volunteers welcome
- Sponsor
- Hyagriv Simhan
Necrotic Pulp
Chitosan,Chitosan Nanoparticles,and Chlorhexidine Gluconate, as Intra Canal Medicaments in Primary Teeth
Aim of the present study is to assess the in vivo susceptibility of root canal bacteria to Chitosan,Chitosan nanoparticles ,and Chlorhexidine gluconate when used as intra canal medicaments in necrotic primary molars
- Trial name
- NCT03588351
- Testing
- chitosan nanoparticles gel, chitosan gel, chlorhexidine gluconate
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Ventilator Associated Pneumonia, Nosocomial Pneumonia
Oral Hygiene With Chlorhexidine and Incidence of Ventilator-Associated Pneumonia in Children Submitted to Heart Surgery
Hospital infections play an important role in the increase of patients' morbimortality and hospitalization costs, especially in the case of individuals admitted to intensive care units (ICU) during postoperative heart surgery.
- Conditions
- Ventilator Associated Pneumonia, Nosocomial Pneumonia, Heart Surgery
- Trial name
- NCT00829842
- Testing
- oral hygiene
- Volunteers
- 160 people
- Sponsor
- University of Sao Paulo
Chronic Gingivitis, Plaque Induced
Comparative Evaluation of Guava Leaf Extract and Chlorhexidine Mouthwash in Patients With Chronic Gingivitis
The goal of this clinical trial is to compare the effectiveness of 0.15% guava (Psidium guajava) leaf extract mouth rinse with 0.2% Chlorhexidine (CHX) mouth rinse in reducing plaque accumulation, gingival inflammation, and oral…
- Trial name
- NCT07059572
- Testing
- Group A- 0.15% Guava leaf extract mouthwash group, Group B- 0.2% Chlorhexidine mouthwash
- Where
- Bangladesh
- Volunteers
- 160 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Wound Heal, Wound Surgical
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II
The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the…
- Conditions
- Wound Heal, Wound Surgical, Oral Soft Tissue Conditions, Chlorhexidine Adverse Reaction
- Trial name
- NCT04276129
- Testing
- periodontal surgery + 24 hr buccal attached gingiva (G) biopsy, post-surgical CHX mouth-rinses indication
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- University of Roma La Sapienza