Clinical trials: Chlorhexidine
Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty
Irrisept C.Acnes Study
A Prospective, Randomized, Controlled Trial Comparing An Irrisept Antiseptic Irrigation With 0.05% Chlorhexidine Gluconate versus Standard of Care Prophylaxis Chlorohexidine Wipes
- Trial name
- NCT03938467
- Testing
- Antiseptic Cleanser
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Associates of Michigan, PC
Periodontitis, Periodontal Disease
Efficacy of Chlorhexidine and Morus Nigra Mouthwashes After Periodontal Treatment
This study aims to evaluate and compare the clinical, biochemical, and microbiological effects of chlorhexidine and Morus nigra (blackberry) mouthwashes used as an adjunct to non-surgical periodontal treatment (scaling and root…
- Trial name
- NCT07540624
- Testing
- 0.12% Chlorhexidine Gluconate Mouthwash, 5% Morus Nigra Mouthwash, Scaling and Root Planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Inonu University
Staphylococcus Aureus
Mupirocin-Iodophor ICU Decolonization Swap Out Trial
The Swap Out Trial is a cluster randomized controlled trial of HCA hospitals, evaluating the non-inferiority of two decolonization regimens: Arm 1 Routine Care: ICU nasal decolonization with mupirocin twice daily for 5 days in…
- Trial name
- NCT03140423
- Testing
- Arm 1. Routine Care (Mupirocin/CHG), Arm 2. Iodophor/CHG Decolonization
- Where
- 137 sites in United States
- Volunteers
- 353,323 people
- Sponsor
- Harvard Pilgrim Health Care
Postoperative Pain
Comparing Two Root Canal Cleaning Solutions (Chlorhexidine vs. Sodium Hypochlorite) for Pain After Treatment
Brief Summary (A short description for the lay public) This study aims to find out if the type of cleaning solution used during a root canal affects the pain a patient feels the next day.
- Trial name
- CHXvsNaOCl-Pai (NCT07453160)
- Testing
- Chlorhexidine gluconate 2%, Sodium hypochlorite 5.25%
- Volunteers
- 90 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Healthcare Associated Infections
Impact of Daily Bathing With Chlorhexidine in the Critical Patient
The search for preventive measure with daily bathing with chlorhexidine in the critical care patient will result in a reduction in patient colonization with multidrug resistant pathogens.
- Trial name
- NCT02870062
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Periodontal Diseases, Periodontitis
Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery
Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions.
- Conditions
- Periodontal Diseases, Periodontitis, Dental Plaque
- Trial name
- NCT04223076
- Testing
- Chlorhexidine 0.2%, Corsodyl, Chlorhexidine 0.2%, Curasept
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- University of Oslo
Periapical Periodontitis
Antibacterial Effectiveness of Two Root Canal Irrigants
The aim of this randomized clinical trial is to compare the antibacterial effects of 1% sodium hypochlorite (NaOCl) and 2% chlorhexidine gluconate (CHX) during retreatment of teeth with apical periodontitis (AP).
- Trial name
- NCT02747082
- Testing
- Retreatment of root-filled teeth with infection
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- University of Oslo
Skin Diseases, Infectious
Effect of Chlorhexidine Skin Cleansing on Skin Flora
Given the potential of skin cleansing with chlorhexidine as a safe, feasible, and cost-effective intervention for reducing neonatal death in developing country settings, this study follows a trial already underway in Nepal to…
- Trial name
- NCT00198679
- Testing
- Chlorhexidine
- Where
- Bangladesh
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Wound
Povidone-Iodine Versus Chlorhexidine in Surgical Wound Care
This comparison examines the effectiveness of povidone-iodine and chlorhexidine in managing iatrogenic wounds in surgical patients.
- Trial name
- NCT06667089
- Testing
- Povidone-Iodine, Chlorhexidine
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- University of Jaén
Periodontal Diseases
Ozonated Water Irrigation as an Adjunct to Periodontal Therapy
The use of chlorhexidine or ozonized water in periodontal pockets accompanying NPT can provide a significant improvement in probing pocket depths compared to conventional treatment.
- Trial name
- NCT04556708
- Testing
- salin irrigation, ozonated water irrigation, chlorhexidine irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Abant Izzet Baysal University
Oral Hygiene, Intensive Care
Effect of Toothbrushing Without Chlorhexidine on Oral Hygiene Indices in Patients With Orotracheal Intubation
The oral hygiene method commonly used in intubated patients orotracheal is tooth brushing (mechanical removal) and washing the oral cavity and the orotracheal tube (TOT) with digluconate solution chlorhexidine (CLX).
- Conditions
- Oral Hygiene, Intensive Care, Chlorhexidine
- Trial name
- NCT06453122
- Testing
- Oral care
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Catheterization
Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
The purpose of this study is to prevent catheter-related infections in newborn infants admitted to the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT00516360
- Testing
- 3.15% chlorhexidine as daily antiseptic on needleless access port
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dental Caries
Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth
The purpose of this study is to evaluate the effectiveness of silver diamine fluoride (SDF) compared to chlorhexidine (CHX) as a cavity disinfectant in primary molars after Atraumatic Restorative Treatment approach (ART).
- Trial name
- NCT03855527
- Testing
- Silver Diamine Fluoride, Chlorhexidine, Atraumatic Restorative Treatment without Disinfection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nourhan M.Aly
Coronary Stenosis
Excel Drug-Eluting Stent Pilot Clinical Registry
The Trial aims to evaluate long-term efficiency of Excel stent in the inhibition of restenosis as well as the safety after the cessation of the 6-month anti-platelet drug treatment.
- Trial name
- NCT00385905
- Testing
- Excel Drug-eluting stent
- Where
- China
- Volunteers
- 100 people
- Sponsor
- JW Medical Systems Ltd
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Stem Cell Transplant Complications
A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients
This study evaluates the use of 2% CHG washcloths in an outpatient setting for adults after hematopoietic stem cell transplant in prevention of central line associated blood stream infections.
- Trial name
- NCT03030989
- Testing
- Chlorhexidine Gluconate 2% Wipe
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Infant, Newborn, Diseases, Sepsis
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
The purpose of this study is to evaluate whether use of the disinfectant chlorhexidine administered to the birth canal during labour and newborn at delivery can protect a woman and her baby from bacterial infections after birth.
- Conditions
- Infant, Newborn, Diseases, Sepsis, Puerperal Infection
- Trial name
- NCT00136370
- Testing
- Chlorhexidine, Birth canal wipe, sterile water external genital wipe
- Where
- South Africa
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Periodontal Diseases, Gingivitis
Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract
Chlorhexidine is considered as gold standard for its antiplaque and antigingivitis efficacy till date but it has got many side effects.
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis
- Trial name
- NCT03474146
- Testing
- Ocimum sanctum, Chlorhexidine Gluconate, Propylene Glycol
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Peritoneal Dialysis Catheter Exit Site Infection
Daily Chlorhexidine Care at the Exit Site in Peritoneal Dialysis Patients
Chlorhexidine is used in central line dressing changes and is effective in reducing line infections. It is unclear if daily chlorhexidine care at the exit site in peritoneal dialysis (PD) patients can reduce the risk of…
- Trial name
- NCT02446158
- Testing
- Chlorhexidine gluconate
- Volunteers
- 89 people
- Sponsor
- E-DA Hospital