Clinical trials: Cholecystectomy, Laparoscopic
Cholecystitis, Cholelithiasis
Fluorescent Cholangiography vs White Light for Bile Ducts Identification
The Study is designed to compare the effectiveness of Near Infrared Fluorescence Cholangiography (NIFC) to standard white light imaging (WLI) in visualizing and identifying the main biliary and hepatic structures (Cystic Duct…
- Trial name
- NCT02702843
- Testing
- Laparoscopic cholecystectomy with Xenon light, Laparoscopic cholecystectomy (fluorescent cholangiography)
- Where
- 7 sites in United States, Argentina and 3 more
- Volunteers
- 677 people
- Sponsor
- The Cleveland Clinic
Postoperative Nausea
Aprepitant for Post-operative Nausea
Anesthesia, especially for laparoscopic surgery, can cause post-operative nausea and vomiting. Most patients are given two drugs, decadron and ondansetron, to try to minimize this.
- Trial name
- NCT01020903
- Testing
- Aprepitant
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Northwell Health
Urinary Retention Postoperative, Laparoscopic Cholecystectomy
Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex
This study is intended to be a single-site, prospective, randomized, controlled study that intends to enroll a total of 230 patients undergoing laparoscopic cholecystectomy at Parkland Hospital.
- Conditions
- Urinary Retention Postoperative, Laparoscopic Cholecystectomy, Neuromuscular Blockade, Sugammadex
- Trial name
- NCT05794503
- Testing
- Neostigmine, Sugammadex
- Where
- United States
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Peritoneal Damage
Peritoneal Damage in Laparoscopic Surgery
The investigators hypothesized that applying a low intraperitoneal pressure pneumoperitoneum (≤ 8mmHg) during laparoscopic cholecystectomy, the adverse impact on the surgical peritoneal environment (measured as gene expression of…
- Trial name
- NCT03020641
- Testing
- Low pressure pneumoperitoneum, standard pneumoperitoneum pressure
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Cholecystectomy, Laparoscopic
The Muscle Relaxation-study
The purpose of this investigation is to compare the surgical conditions during laparoscopic cholecystectomy at a low intra-abdominal pressure with deep or moderate muscle relaxation.
- Trial name
- NCT01523886
- Testing
- Rocuronium
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- Herlev Hospital
Gallbladder Disease
A Trial to Evaluate Natural Orifice Transvaginal Endoscopic Cholecystectomy With Laparoscopic Assistance
The study will document being able to successfully remove a subject's gallbladder through the vagina (laparoscopic visualization)using a small collection of study surgical tools.
- Trial name
- NOTES (NCT00889928)
- Testing
- NOTES GEN 1 Toolbox
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Ethicon Endo-Surgery
Pain Management
The Efficacy of Thoracoabdominal Nerve Block With Serratus Intercostal Plane and Rectus Sheath Block in Cholecystectomy
Cholecystectomy is a widespread surgical procedure performed worldwide for acute cholecystitis. This operation can be performed using open surgery or laparoscopic techniques.
- Trial name
- NCT06241794
- Testing
- Group M-TAPA, Group Serratus Intercostal Plane Block and Rectus Sheath Block
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hitit University
Pulmonary Atelectasis
Effect of Recruitment Maneuver on Postoperative Atelectasis Assessed by Lung Ultrasound in Laparoscopic Cholecystectomy
This single-centre, prospective, randomized, parallel-group controlled trial evaluated whether alveolar recruitment manoeuvres (RMs) added to a lung-protective ventilation strategy improve perioperative lung aeration in adults…
- Trial name
- LUNG USG SCORE (NCT07324122)
- Testing
- Alveolar recruitment manoeuvre, Lung-protective ventilation with lung ultrasound assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Acute Cholecystitis, Cholecystectomy
Laparoscopic Cholecystectomy for Acute Cholecystitis After 72 Hours of Symptoms
The purpose of this study is to compare the clinical outcomes of early versus delayed laparoscopic cholecystectomies for acute cholecystitis with more than 72 hours of symptoms.
- Trial name
- NCT01548339
- Testing
- Laparoscopic cholecystectomy
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Lausanne Hospitals
Postoperative Pain, Postoperative Nausea
IV Acetaminophen for Postoperative Analgesia
The purpose of this study is to evaluate the use of IV acetaminophen for postoperative pain management after laparoscopic cholecystectomy to determine if its use to supplement standard of care pain management decreases the…
- Conditions
- Postoperative Pain, Postoperative Nausea, Postoperative Vomiting
- Trial name
- NCT01798316
- Testing
- IV Acetaminophen, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 105 people
- Sponsor
- Northwell Health
Pain, Postoperative
Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients
The objective of this study is to assess the efficacy of paravertebral nerve blocks, single shot, with ropivacaine 0.5% for postoperative pain control after elective laparoscopic cholecystectomy as compared with incisional…
- Trial name
- NCT01380834
- Testing
- control group, treatment group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mihaela Visoiu
Post Operative Pain
Trial of Extended Release Bupivacaine for Pain Relief After Surgery
This is a research study of SABER® -Bupivacaine, an experimental medication designed to reduce pain for up to 3 days after surgery.
- Trial name
- PERSIST (NCT02574520)
- Testing
- SABER-Bupivacaine (Part 1), SABER-Bupivacaine (Part 2), Bupivacaine HCl
- Where
- 21 sites in United States
- Volunteers
- 399 people
- Sponsor
- Durect
Postoperative Pain
Pain After Laparoscopic Cholecystectomy
To the investigators' knowledge, no study has looked at differences in postoperative pain when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and propofol in laparoscopic cholecystectomy.
- Trial name
- NCT00983918
- Testing
- Desflurane, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Gall Stone Disease, Polyp
Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy
The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC).
- Trial name
- NCT02317510
- Testing
- combined anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Gallbladder Disease
A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)
The purpose of this pilot study is to compare the use of deep or standard neuromuscular blockade (NMB) in combination with low or standard insufflation pressure in participants undergoing a surgical procedure, laparoscopic…
- Trial name
- NCT01728584
- Testing
- Rocuronium, Insufflation, Sugammadex
- Where
- 2 sites in Germany, Italy
- Volunteers
- 127 people
- Sponsor
- Merck Sharp & Dohme LLC
Postcholecystectomy Syndrome
Effect of Rowachol on Prevention of Postcholecystectomy Syndrome
Postcholecystectomy syndrome (PCS) includes a heterogeneous group of diseases, usually manifested by the presence of abdominal symptoms following gallbladder removal.
- Trial name
- NCT01765465
- Testing
- Rowachol
- Where
- 2 sites in South Korea
- Volunteers
- 138 people
- Sponsor
- DongGuk University